STRINGSTRING
AFZ04485.1 AFZ04485.1 ilvC ilvC AFY99717.1 AFY99717.1 dxr dxr AFZ00536.1 AFZ00536.1 zwf zwf AFZ01080.1 AFZ01080.1 AFZ01168.1 AFZ01168.1 AFZ01371.1 AFZ01371.1 AFZ01860.1 AFZ01860.1 hisD hisD AFZ02096.1 AFZ02096.1 fcl fcl gpsA gpsA AFZ02690.1 AFZ02690.1 AFZ02752.1 AFZ02752.1 AFZ02758.1 AFZ02758.1 AFZ02782.1 AFZ02782.1 AFZ02824.1 AFZ02824.1 AFZ02916.1 AFZ02916.1 murB murB AFZ03077.1 AFZ03077.1 leuB leuB aroE aroE hisD-2 hisD-2 AFZ03698.1 AFZ03698.1 pdxA pdxA AFZ04037.1 AFZ04037.1 AFZ04053.1 AFZ04053.1 AFZ04148.1 AFZ04148.1 AFZ04156.1 AFZ04156.1 AFZ04342.1 AFZ04342.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AFZ04485.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: ana:alr0658 UDP-glucose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: UDP-glucose 6 [...] (461 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
AFY99717.1dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase; COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: npu:Npun_F3747 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase. (289 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (415 aa)
AFZ00536.13-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa)
AFZ01080.1PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; TIGRFAM: nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026; KEGG: cyj:Cyan7822_5295 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Nucleotide sugar dehydrogenase. (251 aa)
AFZ01168.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (298 aa)
AFZ01371.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: srm:SRM_00889 IMP dehydrogenase / GMP reductase domain, putative; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; SPTR: IMP dehydrogenase / GMP reductase domain, putative. (342 aa)
AFZ01860.1PFAM: Iron-containing alcohol dehydrogenase; COGs: COG0371 Glycerol dehydrogenase; InterPro IPR001670; KEGG: ava:Ava_0016 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Glycerol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase. (396 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
AFZ02096.1Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain; COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: amr:AM1_A0066 riboflavin biosynthesis protein RibD domain-containing protein; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: Riboflavin biosynthesis protein RibD C-terminus domain protein. (196 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (314 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; InterPro IPR011128:IPR006109:IPR006168; KEGG: npu:Npun_F0995 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydro [...] (353 aa)
AFZ02690.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
AFZ02752.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: npu:Npun_R2418 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; SPTR: Alcohol dehydrogenase GroES domain protein. (398 aa)
AFZ02758.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; D-3-phosphoglycerate dehydrogenase; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: ana:alr1890 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: [...] (526 aa)
AFZ02782.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: naz:Aazo_4841 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. (463 aa)
AFZ02824.1Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain; COGs: COG0262 Dihydrofolate reductase; InterPro IPR002734; KEGG: npu:Npun_F5375 deaminase-reductase domain-containing protein; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: Bifunctional deaminase-reductase domain protein. (176 aa)
AFZ02916.1PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439:IPR001804; KEGG: ana:alr1827 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic. (472 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (330 aa)
AFZ03077.1D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: ana:alr0058 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: D-lactate dehydrogenase; SPTR: D-lactate dehydrogenase. (341 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (306 aa)
hisD-2Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
AFZ03698.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (390 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (352 aa)
AFZ04037.1Hopanoid-associated sugar epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR017829; KEGG: ana:alr4268 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Alr4268 protein; TIGRFAM: Hopanoid-associated sugar epimerase. (326 aa)
AFZ04053.1Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; ACT domain; COGs: COG0281 Malic enzyme; InterPro IPR012302:IPR002912:IPR012301; KEGG: npu:Npun_F1023 malic enzyme, NAD-binding; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Amino acid-binding ACT; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SMART: Malic enzyme, NAD-binding; SPTR: Malic enzyme, NAD-binding. (463 aa)
AFZ04148.1PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein; COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR005992; KEGG: ava:Ava_2653 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; SPTR: IMP dehydrogenase related 2; TIGRFAM: IMP dehydrogenase-related 2. (387 aa)
AFZ04156.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COGs: COG1062 Zn-dependent alcohol dehydrogenase class III; InterPro IPR020843:IPR013154:IPR013149:IPR014183; KEGG: npu:Npun_R1946 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; SMART: Polyketide synthase, enoylreductase; SPTR: Alcohol dehydrogenase, zinc-binding domain protein; TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the z [...] (381 aa)
AFZ04342.1Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR002734; KEGG: ava:Ava_0803 bifunctional deaminase-reductase-like; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: Bifunctional deaminase-reductase-like protein. (232 aa)
Your Current Organism:
Calothrix sp. PCC6303
NCBI taxonomy Id: 1170562
Other names: C. sp. PCC 6303, Calothrix sp. (ATCC 29156), Calothrix sp. (PCC 6303), Calothrix sp. ATCC 29156, Calothrix sp. PCC 6303
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