STRINGSTRING
AFY99845.1 AFY99845.1 AFZ00155.1 AFZ00155.1 purU purU pheA pheA AFZ02345.1 AFZ02345.1 AFZ02758.1 AFZ02758.1 AFZ02782.1 AFZ02782.1 AFZ04053.1 AFZ04053.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFY99845.1(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (758 aa)
AFZ00155.1PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789:IPR002912:IPR019455; KEGG: npu:Npun_F1890 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit. (172 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
pheAPFAM: Prephenate dehydratase; ACT domain; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: npu:Npun_R3887 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase. (290 aa)
AFZ02345.1Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: npu:Npun_R4597 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class. (598 aa)
AFZ02758.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; D-3-phosphoglycerate dehydrogenase; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: ana:alr1890 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: [...] (526 aa)
AFZ02782.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: naz:Aazo_4841 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. (463 aa)
AFZ04053.1Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; ACT domain; COGs: COG0281 Malic enzyme; InterPro IPR012302:IPR002912:IPR012301; KEGG: npu:Npun_F1023 malic enzyme, NAD-binding; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Amino acid-binding ACT; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SMART: Malic enzyme, NAD-binding; SPTR: Malic enzyme, NAD-binding. (463 aa)
Your Current Organism:
Calothrix sp. PCC6303
NCBI taxonomy Id: 1170562
Other names: C. sp. PCC 6303, Calothrix sp. (ATCC 29156), Calothrix sp. (PCC 6303), Calothrix sp. ATCC 29156, Calothrix sp. PCC 6303
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