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| | carA | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (388 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (348 aa) |
| | AFV91073.1 | Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa) |
| | AFV91046.1 | Aminotransferase, class IV. (290 aa) |
| | AFV91011.1 | Aminotransferase class I and II. (418 aa) |
| | AFV91008.1 | Alanine racemase, N-terminal domain-containing protein. (365 aa) |
| | AFV90920.1 | 4-phosphoerythronate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (364 aa) |
| | AFV90885.1 | 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa) |
| | AFV90881.1 | Peptidase M20. (397 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (408 aa) |
| | pheA | Prephenate dehydratase. (318 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (472 aa) |
| | mmuM | Homocysteine methyltransferase. (315 aa) |
| | AFV90666.1 | Aminotransferase, class IV. (290 aa) |
| | AFV90642.1 | FAD dependent oxidoreductase. (448 aa) |
| | AFV90638.1 | Branched-chain amino acid aminotransferase. (290 aa) |
| | AFV90573.1 | Proline dehydrogenase. (316 aa) |
| | asd | Semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (265 aa) |
| | ilvA | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (543 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (642 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (225 aa) |
| | ansA | L-asparaginase I. (330 aa) |
| | AFV90482.1 | Peptidase dimerization domain-containing protein. (449 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (505 aa) |
| | AFV90450.1 | Bifunctional deaminase-reductase domain-containing protein. (222 aa) |
| | AFV90397.1 | Ethanolamine ammonia-lyase, large subunit. (479 aa) |
| | eutC | Ethanolamine ammonia-lyase small subunit; Belongs to the EutC family. (261 aa) |
| | glnS | Glutamine--tRNA ligase. (574 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (466 aa) |
| | AFV90305.1 | Glutamine amidotransferase class-I. (229 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa) |
| | cysE | Serine acetyltransferase. (207 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (517 aa) |
| | folD | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (596 aa) |
| | AFV90212.1 | Acetylornithine aminotransferase apoenzyme. (408 aa) |
| | arcA | Arginine deiminase. (421 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (171 aa) |
| | AFV90158.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa) |
| | AFV90156.1 | Riboflavin biosynthesis protein RibD. (192 aa) |
| | AFV90152.1 | Putative glutamine amidotransferase. (281 aa) |
| | AFV90151.1 | CobB/CobQ-like protein. (242 aa) |
| | lysS-2 | Lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (1081 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (869 aa) |
| | aspA | Aspartate ammonia-lyase. (484 aa) |
| | AFV89987.1 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (585 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa) |
| | AFV89951.1 | Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family. (579 aa) |
| | AFV89924.1 | Amidohydrolase family protein. (392 aa) |
| | AFV89892.1 | Peptidase dimerization domain-containing protein. (450 aa) |
| | his2 | Phosphoribosyl-ATP pyrophosphatase. (88 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (567 aa) |
| | AFV89868.1 | Glutamyl-Q tRNA(Asp) synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (347 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa) |
| | AFV89858.1 | Acetolactate synthase. (595 aa) |
| | ilvH | Acetolactate synthase, small subunit. (172 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (342 aa) |
| | leuB | 3-isopropylmalate dehydrogenase. (358 aa) |
| | ilvE | Branched-chain-amino-acid transaminase. (363 aa) |
| | AFV89849.1 | 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (535 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (471 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (348 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (388 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (316 aa) |
| | argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (412 aa) |
| | AFV89825.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (310 aa) |
| | arlY | Argininosuccinate lyase. (476 aa) |
| | trpS | Tryptophan--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (365 aa) |
| | AFV89787.1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (396 aa) |
| | AFV89786.1 | Histidinol-phosphate phosphatase HisN. (261 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (473 aa) |
| | AFV89769.1 | Homoserine dehydrogenase. (447 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (302 aa) |
| | AFV89751.1 | Asparagine synthase (Glutamine-hydrolyzing). (618 aa) |
| | AFV89745.1 | Asparagine synthase (Glutamine-hydrolyzing). (662 aa) |
| | AFV89743.1 | Hexapeptide transferase family protein. (196 aa) |
| | AFV89706.1 | Methionine synthase, vitamin-B12 independent. (331 aa) |
| | pdxT | Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (202 aa) |
| | cysK | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | AFV89643.1 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. (468 aa) |
| | glyQS | Glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (481 aa) |
| | his3 | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (119 aa) |
| | trpE | Anthranilate synthase component I. (522 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (423 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (281 aa) |
| | AFV89625.1 | Glutamate synthase [NADPH], large chain. (1507 aa) |
| | gltD | Glutamate synthase small subunit. (489 aa) |
| | hisX | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa) |
| | his8 | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (396 aa) |
| | his7 | Imidazoleglycerol-phosphate dehydratase. (205 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (208 aa) |
| | his4 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (252 aa) |
| | AFV89599.1 | Putative threonine synthase. (476 aa) |
| | AFV89596.1 | Histidyl-tRNA synthetase. (452 aa) |
| | aspS | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (603 aa) |
| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (893 aa) |
| | AFV89581.1 | Putative shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (274 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (400 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (185 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | metH | Methionine synthase (5-methyltetrahydrofolate:L-homocysteine S-methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1174 aa) |
| | AFV89553.1 | Prephenate dehydrogenase. (364 aa) |
| | AFV89530.1 | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (404 aa) |
| | AFV89522.1 | L-threonine aldolase. (364 aa) |
| | metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (414 aa) |
| | mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (246 aa) |
| | gcvH | Glycine cleavage system H protein 2. (129 aa) |
| | thrS | Threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (688 aa) |
| | dapF | Diaminopimelate epimerase; Belongs to the diaminopimelate epimerase family. (251 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1062 aa) |
| | AFV89259.1 | Glutamine amidotransferase, class-II. (270 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (585 aa) |
| | leuS | Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (842 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (390 aa) |
| | gcsT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (373 aa) |
| | gcvH-2 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa) |
| | gcsP | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (988 aa) |
| | metF | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (305 aa) |
| | AFV89068.1 | 3-deoxy-7-phosphoheptulonate synthase; Belongs to the class-II DAHP synthase family. (448 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa) |
| | glnA | Glutamine synthetase. (473 aa) |
| | AFV89017.1 | Glutamine synthetase type I. (444 aa) |
| | gabT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase. (361 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (318 aa) |
| | AFV88962.1 | Proline dehydrogenase/aldehyde dehydrogenase (NAD) family protein; Belongs to the aldehyde dehydrogenase family. (1200 aa) |
| | AFV88913.1 | Riboflavin biosynthesis protein RibD C-domain-containing protein. (190 aa) |
| | AFV88912.1 | Pyrimidine reductase protein (Dihydrofolate reductase family). (185 aa) |
| | AFV88895.1 | Putative GNAT-family acetyltransferase. (128 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (420 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (186 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (839 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (369 aa) |
| | AFV88785.1 | Riboflavin biosynthesis protein RibD domain-containing protein. (199 aa) |
| | AFV88770.1 | Epi-inositol hydrolase; Belongs to the TPP enzyme family. (634 aa) |
| | AFV88761.1 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (374 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (484 aa) |
| | metB | Cystathionine gamma-synthase (O-succinylhomoserine (Thiol)-lyase). (387 aa) |
| | cysS | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (480 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (488 aa) |
| | AFV88662.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa) |
| | AFV88535.1 | Phosphoserine phosphatase SerB. (288 aa) |
| | AFV88515.1 | Pyrroline-5-carboxylate reductase. (258 aa) |
| | AFV88513.1 | Aspartate ammonia-lyase. (482 aa) |
| | argS | Arginyl-tRNA synthetase. (556 aa) |
| | AFV88460.1 | Aspartate kinase, monofunctional; Belongs to the aspartokinase family. (424 aa) |
| | AFV88459.1 | Hypothetical protein; DUF1707. (163 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1108 aa) |
| | pabA | Glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. (215 aa) |
| | lysS | Lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (517 aa) |
| | AFV88403.1 | Putative Asp/Glu racemase. (241 aa) |
| | AFV88398.1 | Amidase, hydantoinase/carbamoylase family. (442 aa) |
| | arcC | Carbamate kinase; Belongs to the carbamate kinase family. (325 aa) |
| | AFV88359.1 | Pyridine nucleotide-disulfide oxidoreductase family protein associated with PFOR. (610 aa) |
| | AFV88336.1 | 3-mercaptopyruvate sulfurtransferase. (290 aa) |
| | AFV88267.1 | Acetylornithine deacetylase-related deacylase. (446 aa) |
| | AFV88239.1 | Cysteine synthase. (395 aa) |
| | AFV88237.1 | Diaminopimelate decarboxylase. (569 aa) |
| | AFV88213.1 | Aminoglycoside phosphotransferase. (431 aa) |
| | AFV88212.1 | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | AFV88191.1 | Peptidase, M20 (Glutamate carboxypeptidase) family. (437 aa) |
| | AFV88187.1 | Glutamine amidotransferase. (237 aa) |
| | AFV88159.1 | Putative peptidase M20 family protein. (367 aa) |
| | AFV88155.1 | Branched-chain amino acid aminotransferase. (311 aa) |
| | AFV88130.1 | Integral membrane protein. (213 aa) |
| | AFV88049.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa) |
| | AFV88040.1 | Putative molybdopterin synthase sulfurylase MoeB. (383 aa) |
| | pat | Putative phenylalanine aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (401 aa) |
| | AFV87892.1 | Methionine synthase II (Cobalamin-independent). (392 aa) |
| | AFV87888.1 | Thiamine pyrophosphate protein TPP binding domain-containing protein; Belongs to the TPP enzyme family. (551 aa) |
