(25 nodes) Mixed, incl. Glycerolipid metabolism, and glycerol-3-phosphate dehydrogenase complex network (Streptomyces globisporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WQO_00185	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	WQO_00190	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	WQO_01785	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
	WQO_01790	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
	WQO_01795	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
	WQO_02965	Aquaporin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (281 aa)
	glpK	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (505 aa)
	WQO_05560	Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
	WQO_05565	RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
	WQO_05570	Glycerophosphodiester phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
	WQO_05575	Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	WQO_05920	Sphingosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
	WQO_06040	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
	WQO_06050	IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
	WQO_06055	Glycerol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
	glpK-2	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (514 aa)
	WQO_06065	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
	WQO_06070	Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
	WQO_06075	Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
	WQO_06600	Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	WQO_07785	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
	WQO_12395	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
	WQO_21795	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
	gpsA	Glycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (336 aa)
	WQO_27575	Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)

Your Current Organism:

Streptomyces globisporus

NCBI taxonomy Id: 1172567
Other names: S. globisporus C-1027, Streptomyces globisporus C-1027

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WQO_00185	WQO_00190	WQO_00185	WQO_00190	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
WQO_00185	WQO_01785	WQO_00185	WQO_01785	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
WQO_00185	WQO_01790	WQO_00185	WQO_01790	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
WQO_00185	WQO_01795	WQO_00185	WQO_01795	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
WQO_00185	WQO_06055	WQO_00185	WQO_06055	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.402
WQO_00185	WQO_06065	WQO_00185	WQO_06065	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
WQO_00185	WQO_21795	WQO_00185	WQO_21795	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
WQO_00185	gpsA	WQO_00185	WQO_25895	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.818
WQO_00190	WQO_00185	WQO_00190	WQO_00185	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
WQO_00190	WQO_01785	WQO_00190	WQO_01785	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
WQO_00190	WQO_01790	WQO_00190	WQO_01790	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
WQO_00190	WQO_01795	WQO_00190	WQO_01795	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
WQO_00190	WQO_06065	WQO_00190	WQO_06065	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
WQO_00190	WQO_21795	WQO_00190	WQO_21795	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
WQO_00190	gpsA	WQO_00190	WQO_25895	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.818
WQO_01785	WQO_00185	WQO_01785	WQO_00185	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
WQO_01785	WQO_00190	WQO_01785	WQO_00190	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
WQO_01785	WQO_01790	WQO_01785	WQO_01790	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
WQO_01785	WQO_01795	WQO_01785	WQO_01795	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
WQO_01785	WQO_06065	WQO_01785	WQO_06065	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822