(23 nodes) Sulfur metabolism network (Streptomyces globisporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	metXA	Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (403 aa)
	WQO_02350	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
	WQO_03930	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	ssuB	Aliphatic sulfonate ABC transporter ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system. (299 aa)
	WQO_03940	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
	WQO_03945	Catalyzes the release of sulfite from alkanesulfonates; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
	WQO_04420	Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (1393 aa)
	WQO_07220	Alkanesulfonate monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
	WQO_07230	NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
	WQO_07240	Dimethyl sulfone monooxygenase SfnG; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
	WQO_15790	Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
	WQO_16710	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
	WQO_18380	3-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
	WQO_20565	DoxX family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
	WQO_20730	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	WQO_21865	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
	WQO_22575	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
	WQO_27125	3-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
	WQO_28285	Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (444 aa)
	WQO_28290	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
	cysC	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (181 aa)
	WQO_28300	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (238 aa)
	WQO_28310	Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (565 aa)

Your Current Organism:

Streptomyces globisporus

NCBI taxonomy Id: 1172567
Other names: S. globisporus C-1027, Streptomyces globisporus C-1027

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WQO_02350	WQO_04420	WQO_02350	WQO_04420	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.	0.952
WQO_02350	WQO_15790	WQO_02350	WQO_15790	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
WQO_02350	WQO_18380	WQO_02350	WQO_18380	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
WQO_02350	WQO_22575	WQO_02350	WQO_22575	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.960
WQO_02350	WQO_27125	WQO_02350	WQO_27125	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
WQO_02350	WQO_28285	WQO_02350	WQO_28285	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.	0.508
WQO_02350	WQO_28290	WQO_02350	WQO_28290	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.425
WQO_02350	WQO_28300	WQO_02350	WQO_28300	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.	0.425
WQO_02350	WQO_28310	WQO_02350	WQO_28310	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.940
WQO_02350	cysC	WQO_02350	WQO_28295	Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.	0.540
WQO_03930	WQO_03940	WQO_03930	WQO_03940	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
WQO_03930	WQO_03945	WQO_03930	WQO_03945	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the release of sulfite from alkanesulfonates; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
WQO_03930	WQO_07220	WQO_03930	WQO_07220	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alkanesulfonate monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.977
WQO_03930	WQO_07230	WQO_03930	WQO_07230	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.952
WQO_03930	WQO_07240	WQO_03930	WQO_07240	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dimethyl sulfone monooxygenase SfnG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.615
WQO_03930	WQO_16710	WQO_03930	WQO_16710	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
WQO_03930	WQO_20730	WQO_03930	WQO_20730	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
WQO_03930	ssuB	WQO_03930	WQO_03935	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aliphatic sulfonate ABC transporter ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.	0.996
WQO_03940	WQO_03930	WQO_03940	WQO_03930	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
WQO_03940	WQO_03945	WQO_03940	WQO_03945	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the release of sulfite from alkanesulfonates; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996