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aroQ aroQ AFY64599.1 AFY64599.1 hisF hisF hisC hisC trpA trpA hisB hisB AFY65440.1 AFY65440.1 trpB trpB aroC aroC hisZ hisZ trpC trpC AFY65757.1 AFY65757.1 AFY65864.1 AFY65864.1 trpF trpF AFY66112.1 AFY66112.1 hisI hisI AFY66176.1 AFY66176.1 hisA hisA aroB aroB aroA aroA pheA pheA hisD hisD AFY67407.1 AFY67407.1 aroE aroE aroK aroK hisH hisH trpE trpE AFY68171.1 AFY68171.1 hisG hisG trpD trpD
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aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa)
AFY64599.1Arogenate dehydrogenase (NADP); PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: cyn:Cyan7425_3574 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase. (279 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa)
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005861; KEGG: npu:Npun_R0899 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (409 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa)
hisBPFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR020565; KEGG: cyc:PCC7424_0429 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase. (213 aa)
AFY65440.1PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, clade 2; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890:IPR010118:IPR019999; KEGG: cyn:Cyan7425_1230 anthranilate synthase component I-like protein; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase component I; TIGRFAM: para-aminobenzoate synthase component I. (474 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (434 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa)
hisZhistidyl-tRNA synthetase 2; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (412 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001468; KEGG: ana:alr4746 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (295 aa)
AFY65757.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: npu:Npun_F1044 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (289 aa)
AFY65864.1Anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR017459; KEGG: npu:Npun_F1535 hypothetical protein; PFAM: Glycosyl transferase, family 3-like; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Glycosyl transferase, family 3. (359 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: amr:AM1_1638 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (220 aa)
AFY66112.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218; KEGG: npu:Npun_F0725 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Carboxysome formation protein; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (355 aa)
hisIPFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179:IPR002496:IPR021130; KEGG: naz:Aazo_2676 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-AMP cyclohydrolase domain protein; TIGRFAM: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. (209 aa)
AFY66176.1PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006220:IPR011702:IPR001317:IPR006221:IPR 017926:IPR000991; KEGG: ava:Ava_2780 aminodeoxychorismate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; SPTR: Aminodeoxychorismate synthase, glutamine amidotransferase subunit; TIGRFAM: glutamine amidotransferase of anthranilate synthase. (200 aa)
hisA1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006063:IPR006062; KEGG: cyc:PCC7424_4950 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidaz [...] (255 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (371 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (449 aa)
pheAPFAM: Prephenate dehydratase; ACT domain; COGs: COG0077 Prephenate dehydratase; InterPro IPR018528:IPR001086:IPR002912; KEGG: npu:Npun_R3887 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase domain protein. (283 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (443 aa)
AFY67407.1PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004838:IPR004839:IPR005860; KEGG: cyn:Cyan7425_2490 L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase. (367 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (287 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (194 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa)
trpEAnthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (512 aa)
AFY68171.1PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR001176:IPR004838; KEGG: naz:Aazo_5177 class I/II aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (375 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (227 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (349 aa)
Your Current Organism:
Geitlerinema sp. PCC7407
NCBI taxonomy Id: 1173025
Other names: G. sp. PCC 7407, Geitlerinema sp. ATCC 29126, Geitlerinema sp. CPCC 99, Geitlerinema sp. PCC 7407
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