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prmA prmA ybeY ybeY trmB trmB era era mnmE mnmE truA truA rsmH rsmH AFZ29793.1 AFZ29793.1 AFZ30359.1 AFZ30359.1 mnmG mnmG AFZ30753.1 AFZ30753.1 rsmA rsmA AFZ31965.1 AFZ31965.1 AFZ32103.1 AFZ32103.1 rsfS rsfS AFZ32994.1 AFZ32994.1 AFZ33044.1 AFZ33044.1 rsmG rsmG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prmA(LSU ribosomal protein L11P)-lysine N-methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (292 aa)
ybeYMetalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (179 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (211 aa)
eraGTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (318 aa)
mnmEtRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (459 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (297 aa)
rsmHRibosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (298 aa)
AFZ29793.1PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR013216:IPR001566; KEGG: ana:alr3654 hypothetical protein; PFAM: Deoxyribonuclease/rho motif-related TRAM; Methyltransferase type 11; SPTR: 23S rRNA methyltransferase/RumA; TIGRFAM: 23S rRNA methyltransferase/RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (466 aa)
AFZ30359.1PFAM: PhoH-like protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: npu:Npun_F2860 PhoH family protein; PFAM: PhoH-like protein; SPTR: PhoH family protein. (317 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (642 aa)
AFZ30753.1Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (252 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (273 aa)
AFZ31965.1tRNA/rRNA methyltransferase (SpoU); PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537; KEGG: ava:Ava_1436 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: tRNA/rRNA methyltransferase (SpoU); Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (263 aa)
AFZ32103.1RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: ava:Ava_4413 RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase TrmH, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (313 aa)
rsfSIojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (147 aa)
AFZ32994.1Ras superfamily GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (287 aa)
AFZ33044.1Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
rsmG16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (234 aa)
Your Current Organism:
Gloeocapsa sp. PCC7428
NCBI taxonomy Id: 1173026
Other names: Chroococcus sp. Cey un, G. sp. PCC 7428, Gloeocapsa sp. ATCC 29159, Gloeocapsa sp. PCC 7428
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