STRINGSTRING
AFZ30710.1 AFZ30710.1 dtd dtd cysS cysS anmK anmK proA proA AFZ28705.1 AFZ28705.1 AFZ28706.1 AFZ28706.1 AFZ28736.1 AFZ28736.1 ileS ileS AFZ28745.1 AFZ28745.1 AFZ28765.1 AFZ28765.1 accA accA trpF trpF AFZ28773.1 AFZ28773.1 AFZ28776.1 AFZ28776.1 ilvD ilvD AFZ28833.1 AFZ28833.1 AFZ28843.1 AFZ28843.1 AFZ28846.1 AFZ28846.1 AFZ28857.1 AFZ28857.1 AFZ28928.1 AFZ28928.1 AFZ28935.1 AFZ28935.1 aroC aroC bioB bioB AFZ28960.1 AFZ28960.1 acsA acsA speA speA AFZ28988.1 AFZ28988.1 AFZ29020.1 AFZ29020.1 pfkA pfkA mdh mdh trpD trpD asd asd dapA dapA murQ murQ thrS thrS AFZ29156.1 AFZ29156.1 AFZ29159.1 AFZ29159.1 aroB aroB AFZ29191.1 AFZ29191.1 proS proS AFZ29238.1 AFZ29238.1 trpS trpS AFZ29246.1 AFZ29246.1 AFZ29257.1 AFZ29257.1 argD argD aroA aroA nanE nanE guaA guaA AFZ29341.1 AFZ29341.1 AFZ29352.1 AFZ29352.1 hisI hisI pyrG pyrG argH argH AFZ29432.1 AFZ29432.1 leuA leuA lysS lysS mtnA mtnA glsA glsA AFZ29488.1 AFZ29488.1 hisS hisS gpmI gpmI AFZ29572.1 AFZ29572.1 trpB trpB panB panB AFZ29641.1 AFZ29641.1 proB proB folD folD AFZ29737.1 AFZ29737.1 AFZ29748.1 AFZ29748.1 AFZ29769.1 AFZ29769.1 AFZ29771.1 AFZ29771.1 asnS asnS AFZ29806.1 AFZ29806.1 ispF ispF pheS pheS AFZ29844.1 AFZ29844.1 AFZ29849.1 AFZ29849.1 kdsA kdsA AFZ29893.1 AFZ29893.1 AFZ29894.1 AFZ29894.1 AFZ29937.1 AFZ29937.1 acpP acpP AFZ29939.1 AFZ29939.1 AFZ30022.1 AFZ30022.1 acpS acpS proC proC AFZ30064.1 AFZ30064.1 AFZ30065.1 AFZ30065.1 AFZ30066.1 AFZ30066.1 AFZ30074.1 AFZ30074.1 hisC hisC AFZ30120.1 AFZ30120.1 panC/cmk panC/cmk AFZ30136.1 AFZ30136.1 AFZ30156.1 AFZ30156.1 aspS aspS glyS glyS AFZ30183.1 AFZ30183.1 pdhA pdhA AFZ30199.1 AFZ30199.1 cbiA cbiA dapF dapF trpB-2 trpB-2 thrB thrB AFZ30266.1 AFZ30266.1 ilvA ilvA AFZ30295.1 AFZ30295.1 dxr dxr AFZ30309.1 AFZ30309.1 AFZ30316.1 AFZ30316.1 AFZ30320.1 AFZ30320.1 AFZ30339.1 AFZ30339.1 AFZ30362.1 AFZ30362.1 purF purF AFZ30401.1 AFZ30401.1 AFZ30408.1 AFZ30408.1 hisG hisG AFZ30437.1 AFZ30437.1 AFZ30462.1 AFZ30462.1 panD panD AFZ30504.1 AFZ30504.1 AFZ30542.1 AFZ30542.1 purQ purQ AFZ30558.1 AFZ30558.1 AFZ30563.1 AFZ30563.1 dapL dapL AFZ30672.1 AFZ30672.1 AFZ30679.1 AFZ30679.1 mtnP mtnP AFZ30712.1 AFZ30712.1 hisB hisB AFZ30732.1 AFZ30732.1 AFZ30752.1 AFZ30752.1 tpiA tpiA hisZ hisZ AFZ30803.1 AFZ30803.1 AFZ30841.1 AFZ30841.1 gltX gltX AFZ30861.1 AFZ30861.1 ispE ispE AFZ30883.1 AFZ30883.1 AFZ30895.1 AFZ30895.1 AFZ30928.1 AFZ30928.1 tyrS tyrS AFZ30985.1 AFZ30985.1 AFZ31002.1 AFZ31002.1 AFZ31003.1 AFZ31003.1 AFZ31004.1 AFZ31004.1 AFZ31005.1 AFZ31005.1 AFZ31044.1 AFZ31044.1 fabZ fabZ AFZ31117.1 AFZ31117.1 AFZ31119.1 AFZ31119.1 AFZ31129.1 AFZ31129.1 leuB leuB accD accD pyrB pyrB lysA lysA pheT pheT AFZ31283.1 AFZ31283.1 AFZ31299.1 AFZ31299.1 AFZ31320.1 AFZ31320.1 AFZ31323.1 AFZ31323.1 valS valS AFZ31353.1 AFZ31353.1 argC argC eno eno AFZ31371.1 AFZ31371.1 aroK aroK argB argB argG argG AFZ31429.1 AFZ31429.1 glyA glyA aroQ aroQ AFZ31454.1 AFZ31454.1 AFZ31475.1 AFZ31475.1 gloB gloB AFZ31553.1 AFZ31553.1 AFZ31554.1 AFZ31554.1 AFZ31575.1 AFZ31575.1 AFZ31576.1 AFZ31576.1 AFZ31577.1 AFZ31577.1 AFZ31588.1 AFZ31588.1 dapB dapB AFZ31598.1 AFZ31598.1 AFZ31607.1 AFZ31607.1 AFZ31608.1 AFZ31608.1 AFZ31671.1 AFZ31671.1 trpC trpC AFZ31688.1 AFZ31688.1 glmS glmS AFZ31744.1 AFZ31744.1 AFZ31746.1 AFZ31746.1 AFZ31748.1 AFZ31748.1 AFZ31752.1 AFZ31752.1 AFZ31757.1 AFZ31757.1 glsA-2 glsA-2 proA-2 proA-2 AFZ31791.1 AFZ31791.1 AFZ31819.1 AFZ31819.1 AFZ31855.1 AFZ31855.1 AFZ31856.1 AFZ31856.1 serS serS AFZ31884.1 AFZ31884.1 lipA lipA metG metG plsX plsX fabH fabH AFZ31938.1 AFZ31938.1 aroE aroE dtd3 dtd3 hisD hisD hisC-2 hisC-2 AFZ32052.1 AFZ32052.1 ispD ispD carA carA ppc ppc gcvP gcvP gcvH gcvH gcvT gcvT AFZ32148.1 AFZ32148.1 AFZ32151.1 AFZ32151.1 AFZ32198.1 AFZ32198.1 pheA pheA AFZ32243.1 AFZ32243.1 alaS alaS AFZ32286.1 AFZ32286.1 AFZ32293.1 AFZ32293.1 ispH ispH AFZ32362.1 AFZ32362.1 trpA trpA AFZ32378.1 AFZ32378.1 AFZ32388.1 AFZ32388.1 AFZ32409.1 AFZ32409.1 AFZ32456.1 AFZ32456.1 AFZ32469.1 AFZ32469.1 pfkA-2 pfkA-2 ilvC ilvC AFZ32505.1 AFZ32505.1 AFZ32565.1 AFZ32565.1 glk glk lipA-2 lipA-2 hisA hisA hisF hisF pgi pgi AFZ32717.1 AFZ32717.1 AFZ32719.1 AFZ32719.1 AFZ32731.1 AFZ32731.1 AFZ32732.1 AFZ32732.1 glyQ glyQ hisH hisH AFZ32761.1 AFZ32761.1 argJ argJ nadA nadA argS argS AFZ32801.1 AFZ32801.1 AFZ32817.1 AFZ32817.1 AFZ32899.1 AFZ32899.1 AFZ32900.1 AFZ32900.1 cobQ cobQ AFZ32969.1 AFZ32969.1 pgk pgk carB carB ispG ispG AFZ33105.1 AFZ33105.1 leuS leuS AFZ33115.1 AFZ33115.1 bioD bioD AFZ33155.1 AFZ33155.1 AFZ33157.1 AFZ33157.1 AFZ33173.1 AFZ33173.1 AFZ33178.1 AFZ33178.1 AFZ33210.1 AFZ33210.1 AFZ33227.1 AFZ33227.1 AFZ33240.1 AFZ33240.1 AFZ33244.1 AFZ33244.1 AFZ33247.1 AFZ33247.1 AFZ33248.1 AFZ33248.1 AFZ33249.1 AFZ33249.1 AFZ33250.1 AFZ33250.1 AFZ33251.1 AFZ33251.1 AFZ33252.1 AFZ33252.1 ldh ldh AFZ33294.1 AFZ33294.1
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second shell of interactors
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proteins of unknown 3D structure
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AFZ30710.1PFAM: Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: ava:Ava_0576 aminotransferase, class IV; PFAM: Aminotransferase, class IV; SPTR: Aminotransferase, class IV; manually curated. (264 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (153 aa)
cysSPFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015273:IPR002308; KEGG: npu:Npun_F3946 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (490 aa)
anmKAnhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (433 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa)
AFZ28705.1Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region; COGs: COG3386 Gluconolactonase; InterPro IPR013658; KEGG: npu:Npun_R6059 SMP-30/gluconolaconase/LRE domain-containing protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; PRIAM: Gluconolactonase; SPTR: SMP-30/Gluconolaconase/LRE domain protein. (314 aa)
AFZ28706.1KEGG: npu:Npun_R2975 hypothetical protein; SPTR: Putative uncharacterized protein. (296 aa)
AFZ28736.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (493 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (1093 aa)
AFZ28745.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (386 aa)
AFZ28765.1acyl-ACP reductase; PFAM: Shikimate / quinate 5-dehydrogenase; TIGRFAM: long-chain fatty acyl-ACP reductase (aldehyde-forming); COGs: COG5322 dehydrogenase; InterPro IPR002198; KEGG: ava:Ava_2534 hypothetical protein; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Putative uncharacterized protein. (339 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: ana:all5288 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (237 aa)
AFZ28773.1Beta-alanine--pyruvate transaminase; PFAM: Aminotransferase class-III; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814; KEGG: cyn:Cyan7425_3898 beta alanine--pyruvate transaminase; PFAM: Aminotransferase class-III; PRIAM: Beta-alanine--pyruvate transaminase; SPTR: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
AFZ28776.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (432 aa)
ilvDPFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR000581:IPR004404; KEGG: naz:Aazo_0368 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (560 aa)
AFZ28833.1PFAM: PEP-utilising enzyme, mobile domain; Domain of unknown function (DUF205); Pyruvate phosphate dikinase, PEP/pyruvate binding domain; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR003811:IPR002192:IPR008279; KEGG: npu:Npun_F1309 pyruvate phosphate dikinase, PEP/pyruvate-binding; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; Protein of unknown function DUF205; PEP-utilising enzyme, mobile domain; SPTR: Pyruvate phosphate dikinase, PEP/pyruvate-binding. (976 aa)
AFZ28843.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR002912:IPR006236; KEGG: naz:Aazo_2156 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerat [...] (526 aa)
AFZ28846.13-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
AFZ28857.1KEGG: ana:all4101 hypothetical protein; SPTR: Ycf91-like protein. (127 aa)
AFZ28928.1GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: npu:Npun_R1906 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase. (162 aa)
AFZ28935.1Hypothetical protein; COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; InterPro IPR006311; KEGG: npu:Npun_F1348 hypothetical protein; SPTR: Putative uncharacterized protein. (256 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)
AFZ28960.1PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005815:IPR005814; KEGG: tel:tll1935 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Adenosylmethionine--8-amino-7-oxononanoate transaminase; SPTR: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; TIGRFAM: Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (687 aa)
AFZ28988.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (810 aa)
AFZ29020.1Hypothetical protein; KEGG: gym:GYMC10_2327 aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase. (73 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (360 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (323 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (359 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (354 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (305 aa)
thrSthreonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR002320:IPR012947:IPR002314:IPR004154; KEGG: ana:alr0335 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Threonyl/alanyl tRNA synthetase, SAD; Anticodon-binding; SPTR: Threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; Belongs to the class-II aminoacyl-tRN [...] (607 aa)
AFZ29156.1PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794:IPR008279; KEGG: ava:Ava_1694 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile domain; PRIAM: Pyruvate kinase., Pyruvate, water dikinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; Belongs to the pyruvate kinase family. (587 aa)
AFZ29159.1PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1; COGs: COG4401 Chorismate mutase; InterPro IPR008243; KEGG: cyc:PCC7424_5344 chorismate mutase; PFAM: Chorismate mutase, AroH class; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroH class. (156 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa)
AFZ29191.1Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (180 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (602 aa)
AFZ29238.1PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain; COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310:IPR008286; KEGG: npu:Npun_F0489 Orn/Lys/Arg decarboxylase, major region; PFAM: Orn/Lys/Arg decarboxylase, major domain; Orn/Lys/Arg decarboxylase, C-terminal; PRIAM: Arginine decarboxylase; SPTR: Orn/Lys/Arg decarboxylase, major region. (499 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (335 aa)
AFZ29246.1PFAM: Methylenetetrahydrofolate reductase; COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: ava:Ava_2992 methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (313 aa)
AFZ29257.1InterPro IPR001451; KEGG: ana:all0864 carbon dioxide concentrating mechanism protein; SPTR: Transferase hexapeptide repeat protein. (211 aa)
argDPFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine transaminases; COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR005814:IPR004636; KEGG: ana:alr1080 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine aminotransferase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (425 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (447 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (228 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (534 aa)
AFZ29341.1PFAM: DALR anticodon binding domain; InterPro IPR008909; KEGG: ter:Tery_3617 DALR anticodon binding; PFAM: DALR anticodon binding; SPTR: DALR anticodon binding. (280 aa)
AFZ29352.1PFAM: Protein of unknown function (DUF1565); TIGRFAM: parallel beta-helix repeat (two copies); InterPro IPR011459:IPR006633:IPR006626; KEGG: ava:Ava_5048 hypothetical protein; PFAM: Protein of unknown function DUF1565; SMART: Carbohydrate-binding/sugar hydrolysis domain; Parallel beta-helix repeat; SPTR: Putative uncharacterized protein; TIGRFAM: parallel beta-helix repeat. (575 aa)
hisIPFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein hisIE; InterPro IPR008179:IPR002496:IPR021130; KEGG: naz:Aazo_2676 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosp [...] (215 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
argHPFAM: Lyase; TIGRFAM: argininosuccinate lyase; COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR009049:IPR000362; KEGG: naz:Aazo_1169 argininosuccinate lyase; PFAM: Fumarate lyase; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase. (480 aa)
AFZ29432.13-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese-like domain; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: npu:Npun_R0904 rhodanese domain-containing protein; PFAM: Rhodanese-like; PRIAM: 3-mercaptopyruvate sulfurtransferase; SMART: Rhodanese-like; SPTR: Rhodanese domain protein. (290 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (529 aa)
lysSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; COGs: COG1190 Lysyl-tRNA synthetase (class II); HAMAP: Lysyl-tRNA synthetase, class II; InterPro IPR002313:IPR004365:IPR004364; KEGG: ava:Ava_3150 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (575 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (353 aa)
glsAL-glutaminase; PFAM: Glutaminase; TIGRFAM: glutaminase A; COGs: COG2066 Glutaminase; HAMAP: Glutaminase, core; InterPro IPR015868; KEGG: cyh:Cyan8802_2670 glutaminase; PFAM: Glutaminase, core; PRIAM: Glutaminase; SPTR: Glutaminase; TIGRFAM: Glutaminase, core; Belongs to the glutaminase family. (343 aa)
AFZ29488.1PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: ana:alr3644 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class. (603 aa)
hisSPFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; COGs: COG0124 Histidyl-tRNA synthetase; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR015807:IPR002314:IPR004154; KEGG: cyc:PCC7424_5012 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup. (426 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (533 aa)
AFZ29572.1Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyn:Cyan7425_4559 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. (324 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (453 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (257 aa)
AFZ29641.1PFAM: Rhodanese-like domain; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: ava:Ava_4507 rhodanese-like protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese-like. (291 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
folDBifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa)
AFZ29737.1PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: ava:Ava_0949 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. (175 aa)
AFZ29748.1PFAM: 3-dehydroquinate synthase; COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: npu:Npun_R1267 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase. (400 aa)
AFZ29769.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (390 aa)
AFZ29771.1KEGG: llo:LLO_1865 hypothetical protein; SPTR: Putative uncharacterized protein. (214 aa)
asnSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase; COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase; InterPro IPR004365:IPR004364:IPR004522; KEGG: npu:Npun_R0874 asparaginyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb. (462 aa)
AFZ29806.1SMP-30/Gluconolaconase/LRE-like region-containing protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; COGs: COG3386 Gluconolactonase; InterPro IPR013658; KEGG: npu:Npun_R3479 SMP-30/gluconolaconase/LRE domain-containing protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; SPTR: Putative uncharacterized protein. (293 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (193 aa)
pheSphenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain; InterPro IPR004529:IPR004188:IPR002319; KEGG: npu:Npun_R0940 phenylalanyl-tRNA synthetase subunit alpha; PFAM: Phenylalanyl-tRNA synthetase alpha chain; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA sy [...] (333 aa)
AFZ29844.1PFAM: Asp/Glu/Hydantoin racemase; COGs: COG4126 Hydantoin racemase; InterPro IPR015942; KEGG: mes:Meso_0332 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Hydantoin racemase; SPTR: Asp/Glu racemase. (248 aa)
AFZ29849.1Amidase, hydantoinase/carbamoylase family; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidase, hydantoinase/carbamoylase family; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010158:IPR002933:IPR011650; KEGG: syw:SYNW2452 allantoate amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-carbamoyl-L-amino-acid hydrolase; SPTR: N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: Amidase, hydantoinase/carbamoylase. (412 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; HAMAP: 3-deoxy-8-phosphooctulonate synthase; InterPro IPR006269:IPR006218; KEGG: amr:AM1_2195 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-8-phosphooctulonate synthase; SPTR: 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. (278 aa)
AFZ29893.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218; KEGG: cyt:cce_3366 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Carboxysome formation protein; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2. (361 aa)
AFZ29894.1PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: phenylalanine ammonia-lyase; COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106; KEGG: npu:Npun_R2068 phenylalanine/histidine ammonia-lyase; PFAM: Phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Phenylalanine/histidine ammonia-lyase. (559 aa)
AFZ29937.1Succinate dehydrogenase subunit C; PFAM: Cysteine-rich domain; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: npu:Npun_F4560 hypothetical protein; PFAM: Cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Putative uncharacterized protein. (300 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (83 aa)
AFZ29939.13-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa)
AFZ30022.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218; KEGG: npu:Npun_F0725 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Carboxysome formation protein; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2. (353 aa)
acpSHolo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (129 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
AFZ30064.1Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; COGs: COG3321 Polyketide synthase modules and related protein; InterPro IPR004432:IPR014030:IPR014031:IPR014043; KEGG: npu:Npun_R1294 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Acyl transferase; PRIAM: 6-deoxyerythronolide-B synthase; SPTR: Beta-ketoacyl [...] (1683 aa)
AFZ30065.1PFAM: KR domain; COGs: COG3321 Polyketide synthase modules and related protein; InterPro IPR013968; KEGG: npu:Npun_R1294 beta-ketoacyl synthase; PFAM: Polyketide synthase, KR; SPTR: Beta-ketoacyl synthase. (561 aa)
AFZ30066.1PfaB family protein; PFAM: Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: PfaB family protein; COGs: COG3321 Polyketide synthase modules and related protein; InterPro IPR014181:IPR014030:IPR014031; KEGG: npu:Npun_R1293 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: 6-deoxyerythronolide-B synthase; SPTR: Beta-ketoacyl synthase; TIGRFAM: Omega-3 polyunsaturated fatty acid synthase-like; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases [...] (1086 aa)
AFZ30074.1L-iditol 2-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: npu:Npun_F2709 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: L-iditol 2-dehydrogenase; SPTR: Putative uncharacterized protein. (342 aa)
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR004839:IPR005861; KEGG: npu:Npun_R0899 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (381 aa)
AFZ30120.1Parallel beta-helix repeat protein; PFAM: Protein of unknown function (DUF1565); S-layer homology domain; TIGRFAM: parallel beta-helix repeat (two copies); InterPro IPR006626:IPR011459:IPR001119; KEGG: ana:alr3608 hypothetical protein; PFAM: Protein of unknown function DUF1565; S-layer homology domain; SMART: Parallel beta-helix repeat; SPTR: Alr3608 protein; TIGRFAM: parallel beta-helix repeat. (611 aa)
panC/cmkCytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. (526 aa)
AFZ30136.1Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; ACT domain; COGs: COG0281 Malic enzyme; InterPro IPR002912:IPR012301:IPR012302; KEGG: npu:Npun_F1023 malic enzyme, NAD-binding; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Amino acid-binding ACT; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: Malic enzyme, NAD-binding; manually curated. (463 aa)
AFZ30156.1PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: npu:Npun_F3641 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; PRIAM: Glutamate dehydrogenase (NAD(P)(+)); SPTR: Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (429 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa)
glySPFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit; COGs: COG0751 Glycyl-tRNA synthetase beta subunit; HAMAP: Glycyl-tRNA synthetase, class IIc, beta subunit; InterPro IPR015944:IPR002311; KEGG: ava:Ava_0794 glycyl-tRNA synthetase subunit beta; PFAM: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase beta subunit; TIGRFAM: Glycyl-tRNA synthetase, class IIc, beta subunit. (715 aa)
AFZ30183.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (343 aa)
AFZ30199.1Delta-12 acyl-phospholipid desaturase; PFAM: Fatty acid desaturase; COGs: COG3239 Fatty acid desaturase; InterPro IPR005804; KEGG: ava:Ava_4211 fatty acid desaturase; PFAM: Fatty acid desaturase, type 1; SPTR: Fatty acid desaturase. (347 aa)
cbiACobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (462 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa)
trpB-2Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (319 aa)
AFZ30266.1Arogenate dehydrogenase (NADP); PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: npu:Npun_R0978 arogenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase. (280 aa)
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa)
AFZ30295.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (305 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (397 aa)
AFZ30309.1Fumarate hydratase class II; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: aspartate ammonia-lyase; COGs: COG1027 Aspartate ammonia-lyase; HAMAP: Fumarate hydratase class II; InterPro IPR000362:IPR018951; KEGG: npu:Npun_F2551 aspartate ammonia-lyase; PFAM: Fumarate lyase; Fumarase C, C-terminal; PRIAM: Aspartate ammonia-lyase; SPTR: Aspartate ammonia-lyase. (471 aa)
AFZ30316.1Amine oxidase; PFAM: Flavin containing amine oxidoreductase; COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: gvi:gll1123 hypothetical protein; PFAM: Amine oxidase; SPTR: Putative uncharacterized protein. (541 aa)
AFZ30320.16-deoxyerythronolide-B synthase; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014030:IPR014031:IPR014043:IPR013968:IPR 006163; KEGG: npu:Npun_R3024 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Acyl transferase; Polyketide synthase, KR; Phosphopantetheine-binding; PRIAM: 6-deoxyerythronolide-B synthase; SPTR: JamP. (1551 aa)
AFZ30339.1CoA-binding domain protein; PFAM: CoA binding domain; Acetyltransferase (GNAT) family; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: ava:Ava_4664 GCN5-related N-acetyltransferase; PFAM: CoA-binding; ATP-grasp fold, succinyl-CoA synthetase-type; GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase. (924 aa)
AFZ30362.1Chorismate lyase; PFAM: Protein of unknown function (DUF98); KEGG: npu:Npun_F5952 hypothetical protein; SPTR: Putative uncharacterized protein. (205 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (495 aa)
AFZ30401.1PFAM: Phosphotransferase enzyme family; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: amr:AM1_0146 phosphotransferase family protein, putative; PFAM: Aminoglycoside phosphotransferase; SPTR: Phosphotransferase enzyme family, putative. (324 aa)
AFZ30408.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (214 aa)
AFZ30437.1GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; InterPro IPR000182; KEGG: ava:Ava_4071 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase. (146 aa)
AFZ30462.1LL-diaminopimelate aminotransferase apoenzyme; PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ana:alr2765 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: LL-diaminopimelate aminotransferase; SPTR: Aspartate aminotransferase. (406 aa)
panDL-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
AFZ30504.1PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR017459; KEGG: npu:Npun_F1535 hypothetical protein; PFAM: Glycosyl transferase, family 3, N-terminal; SPTR: Glycosyl transferase, family 3. (358 aa)
AFZ30542.1PFAM: Glutamine amidotransferases class-II; COGs: COG0121 glutamine amidotransferase; InterPro IPR000583; KEGG: naz:Aazo_0160 glutamine amidotransferase class-II; PFAM: Glutamine amidotransferase, class-II; SPTR: Glutamine amidotransferase class-II. (255 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (225 aa)
AFZ30558.1L-iditol 2-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: ava:Ava_0154 zinc-containing alcohol dehydrogenase superfamily protein; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; PRIAM: L-iditol 2-dehydrogenase; SPTR: Zinc-containing alcohol dehydrogenase superfamily. (352 aa)
AFZ30563.1Succinate-semialdehyde dehydrogenase (NAD(P)(+)); PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ana:all3556 succinate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Succinate-semialdehyde dehydrogenase (NAD(P)(+)); SPTR: Succinate-semialdehyde dehydrogenase. (454 aa)
dapLLL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa)
AFZ30672.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (348 aa)
AFZ30679.1PFAM: DeoC/LacD family aldolase; COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: ava:Ava_1590 fructose-bisphosphate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; SPTR: Fructose-bisphosphate aldolase. (360 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (290 aa)
AFZ30712.12-isopropylmalate synthase; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005675; KEGG: ana:alr3522 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Pyruvate carboxyltransferase; PRIAM: (R)-citramalate synthase; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; Belon [...] (542 aa)
hisBPFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: ava:Ava_3285 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase. (216 aa)
AFZ30732.1Enoyl-(acyl-carrier-protein) reductase (NADH); PFAM: short chain dehydrogenase; COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: npu:Npun_R5510 enoyl-(acyl carrier protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: Short-chain dehydrogenase/reductase SDR. (285 aa)
AFZ30752.1PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: npu:Npun_F3640 3-oxoacyl-(acyl carrier protein) synthase II; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (380 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (409 aa)
AFZ30803.1Amidohydrolase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: npu:Npun_F0970 amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase. (394 aa)
AFZ30841.1Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (482 aa)
AFZ30861.1Cysteine desulfurase; PFAM: Aminotransferase class-V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: npu:Npun_F1365 aminotransferase, class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase, class V. (394 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (326 aa)
AFZ30883.1PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: npu:Npun_R4104 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. (343 aa)
AFZ30895.1PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: ana:all1701 hypothetical protein; PFAM: Protein of unknown function DUF39; SPTR: All1701 protein. (393 aa)
AFZ30928.1Phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121; KEGG: npu:Npun_R6166 PEP-utilizing enzyme; PFAM: PEP-utilising enzyme; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate-binding; PRIAM: Pyruvate, water dikinase; SPTR: PEP-utilizing enzyme. (805 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (439 aa)
AFZ30985.1PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: syf:Synpcc7942_2156 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I. (474 aa)
AFZ31002.1Putative sortase-sorted surface protein; TIGRFAM: parallel beta-helix repeat (two copies); InterPro IPR006626; KEGG: cms:CMS_0079 putative sortase-sorted surface protein; SPTR: Putative sortase-sorted surface protein. (574 aa)
AFZ31003.1TIGRFAM: parallel beta-helix repeat (two copies); InterPro IPR006626; KEGG: sen:SACE_3182 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: parallel beta-helix repeat. (565 aa)
AFZ31004.1TIGRFAM: parallel beta-helix repeat (two copies); InterPro IPR006626; KEGG: sen:SACE_3182 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: parallel beta-helix repeat. (563 aa)
AFZ31005.1GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; InterPro IPR000182; KEGG: ana:alr2925 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: Alr2925 protein. (162 aa)
AFZ31044.1PFAM: Metallo-beta-lactamase superfamily; KEGG: ava:Ava_3439 beta-lactamase-like; SPTR: Beta-lactamase-like. (241 aa)
fabZ3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (174 aa)
AFZ31117.1NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: pjd:Pjdr2_0556 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Alcohol dehydrogenase, zinc-containing. (326 aa)
AFZ31119.1PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR011826:IPR006251:IPR001030; KEGG: ter:Tery_2728 homoaconitate hydratase family protein; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: Homoaconitate hydratase family protein; TIGRFAM: Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; Belongs to the [...] (440 aa)
AFZ31129.1GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; InterPro IPR000182; KEGG: amr:AM1_4476 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, gnat family. (171 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (365 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa)
pyrBPFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: npu:Npun_F5181 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspar [...] (329 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (464 aa)
pheTphenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: npu:Npun_F1087 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synth [...] (814 aa)
AFZ31283.1D-amino-acid transaminase; PFAM: Aminotransferase class IV; TIGRFAM: D-amino acid aminotransferase; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: dat:HRM2_24560 IlvE; PFAM: Aminotransferase, class IV; PRIAM: D-amino-acid transaminase; SPTR: IlvE. (277 aa)
AFZ31299.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1206 aa)
AFZ31320.1KEGG: ana:alr4119 hypothetical protein; SPTR: Alr4119 protein. (146 aa)
AFZ31323.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: npu:Npun_R2750 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. (432 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (911 aa)
AFZ31353.18-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (398 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (352 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
AFZ31371.1Lactoylglutathione lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: lactoylglutathione lyase; COGs: COG0346 Lactoylglutathione lyase and related lyase; InterPro IPR004361:IPR004360; KEGG: cyc:PCC7424_4951 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: Lactoylglutathione lyase; SPTR: Lactoylglutathione lyase; TIGRFAM: Glyoxalase I. (144 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (190 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa)
argGPFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: ana:alr4798 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
AFZ31429.15-carboxymethyl-2-hydroxymuconateDelta- isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: ana:alr4803 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PFAM: Fumarylacetoacetase, C-terminal-like; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. (267 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
AFZ31454.1KEGG: npu:Npun_R4714 hypothetical protein; SPTR: Putative uncharacterized protein. (423 aa)
AFZ31475.1acetoacetyl-CoA reductase; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: cyn:Cyan7425_4055 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Short-chain dehydrogenase/reductase SDR. (239 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (257 aa)
AFZ31553.1PFAM: Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697; KEGG: cyn:Cyan7425_1964 peptidase C26; PFAM: Peptidase C26; SPTR: Class I glutamine amidotransferase, putative. (242 aa)
AFZ31554.1PFAM: Glutamine synthetase, catalytic domain; TIGRFAM: glutamine synthetase, type III; COGs: COG0174 Glutamine synthetase; InterPro IPR017536:IPR008146; KEGG: azl:AZL_a09540 glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase, type III; TIGRFAM: Glutamine synthetase, type III. (441 aa)
AFZ31575.1Glutamate synthase (NADPH) GltB2 subunit; PFAM: Conserved region in glutamate synthase; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002932; KEGG: tgr:Tgr7_1701 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; PRIAM: Glutamate synthase (NADPH); SPTR: Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (438 aa)
AFZ31576.1PFAM: GXGXG motif; COGs: COG0070 Glutamate synthase domain 3; InterPro IPR002489; KEGG: tgr:Tgr7_1700 glutamate synthase alpha subunit domain protein; PFAM: Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase alpha subunit domain protein. (233 aa)
AFZ31577.1N-methylglutamate synthase subunit A; PFAM: Glutamine amidotransferases class-II; COGs: COG0067 Glutamate synthase domain 1; InterPro IPR000583; KEGG: meh:M301_1416 glutamine amidotransferase class-II; PFAM: Glutamine amidotransferase, class-II; SPTR: Glutamine amidotransferase class-II. (311 aa)
AFZ31588.1PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: npu:Npun_R6604 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; Mandelate racemase/muconate lactonizing enzyme, N-terminal; SPTR: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein. (348 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (276 aa)
AFZ31598.1KEGG: ava:Ava_0475 hypothetical protein; SPTR: Putative uncharacterized protein. (238 aa)
AFZ31607.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: ana:alr0897 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; SPTR: Alcohol dehydrogenase. (389 aa)
AFZ31608.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: npu:Npun_R6237 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; PRIAM: S-(hydroxymethyl)glutathione dehydrogenase; SPTR: Alcohol dehydrogenase. (389 aa)
AFZ31671.1Serine--glyoxylate transaminase; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: npu:Npun_F4157 aminotransferase, class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--glyoxylate transaminase; SPTR: Aminotransferase, class V. (384 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: ana:alr4746 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (294 aa)
AFZ31688.1PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR006426; KEGG: tgr:Tgr7_0185 asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; Glutamine amidotransferase, class-II; SPTR: Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing. (678 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (631 aa)
AFZ31744.1Long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: npu:Npun_F6411 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-binding enzyme, putative. (655 aa)
AFZ31746.1Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: npu:Npun_F6414 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl atta [...] (441 aa)
AFZ31748.1NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: ana:alr2948 hypothetical protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Alr2948 protein. (334 aa)
AFZ31752.1PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: npu:Npun_F1890 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit. (173 aa)
AFZ31757.1GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; InterPro IPR000182; KEGG: npu:Npun_R2494 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase. (169 aa)
glsA-2L-glutaminase; PFAM: Glutaminase; TIGRFAM: glutaminase A; COGs: COG2066 Glutaminase; HAMAP: Glutaminase, core; InterPro IPR015868; KEGG: npu:Npun_F6494 glutaminase; PFAM: Glutaminase, core; PRIAM: Glutaminase; SPTR: Glutaminase; TIGRFAM: Glutaminase, core; Belongs to the glutaminase family. (343 aa)
proA-2Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa)
AFZ31791.1o-succinylbenzoate--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: ava:Ava_2636 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: AMP-dependent synthetase and ligase. (444 aa)
AFZ31819.1Hypothetical protein; COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: cyn:Cyan7425_4707 hypothetical protein; SPTR: Putative uncharacterized protein. (279 aa)
AFZ31855.1CTP synthase; PFAM: Glutamine amidotransferase class-I; COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR000991; KEGG: esa:ESA_02182 hypothetical protein; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: Putative uncharacterized protein. (238 aa)
AFZ31856.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: ava:Ava_4589 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: [...] (464 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa)
AFZ31884.1PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573:IPR011827; KEGG: ter:Tery_1041 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit, subgroup; Belongs to the LeuD family. (180 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (292 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. (532 aa)
plsXPhosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (348 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (331 aa)
AFZ31938.1PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043; KEGG: ana:alr0240 acyl-carrier-protein S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: Malonyl coenzyme A-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase. (293 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (287 aa)
dtd3Sec-independent protein translocase TatD; Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr). (260 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (446 aa)
hisC-2PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR005861:IPR004839; KEGG: npu:Npun_R0752 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate amino [...] (349 aa)
AFZ32052.1PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439:IPR001804; KEGG: ana:alr1827 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic. (473 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa)
carAPFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: ana:alr1155 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl phosphate synthase, small subunit; Belong [...] (387 aa)
ppcPhosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1025 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (979 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (379 aa)
AFZ32148.1PFAM: CobB/CobQ-like glutamine amidotransferase domain; COGs: COG3442 glutamine amidotransferase; InterPro IPR011698; KEGG: ava:Ava_4286 CobB/CobQ-like glutamine amidotransferase; PFAM: CobB/CobQ-like glutamine amidotransferase; SPTR: CobB/CobQ-like glutamine amidotransferase. (267 aa)
AFZ32151.1PFAM: Phytanoyl-CoA dioxygenase (PhyH); InterPro IPR008775; KEGG: ure:UREG_06243 hypothetical protein; PFAM: Phytanoyl-CoA dioxygenase; SPTR: Putative uncharacterized protein. (318 aa)
AFZ32198.1PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: ava:Ava_1294 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin). (1573 aa)
pheAPFAM: Prephenate dehydratase; ACT domain; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: npu:Npun_R3887 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase domain protein. (287 aa)
AFZ32243.1Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: ava:Ava_2508 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. (320 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (879 aa)
AFZ32286.1L-amino-acid oxidase; PFAM: Flavin containing amine oxidoreductase; COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cyh:Cyan8802_2643 amine oxidase; PFAM: Amine oxidase; PRIAM: L-amino-acid oxidase; SPTR: Amine oxidase. (518 aa)
AFZ32293.1Acetolactate synthase, large subunit; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR012001:IPR012000:IPR011766; KEGG: npu:Npun_R1735 acetolactate synthase 3 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enz [...] (639 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (407 aa)
AFZ32362.1NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: ter:Tery_0561 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (335 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
AFZ32378.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa)
AFZ32388.1PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; delta-1-pyrroline-5-carboxylate dehydrogenase (PutA C-terminal domain); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005932:IPR002872:IPR015590; KEGG: npu:Npun_F5297 putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase; Proline dehydrogenase; SPTR: Putative delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (990 aa)
AFZ32409.1KEGG: npu:Npun_F0538 hypothetical protein; SPTR: Putative uncharacterized protein. (140 aa)
AFZ32456.1NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: cyn:Cyan7425_5428 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (343 aa)
AFZ32469.1Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: ana:alr4552 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. (327 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (354 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
AFZ32505.1PFAM: Radical SAM superfamily; Protein of unknown function (DUF3641); TIGRFAM: radical SAM/Cys-rich domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: npu:Npun_R1900 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein. (332 aa)
AFZ32565.1Export-related chaperone CsaA; PFAM: Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; export-related chaperone CsaA; COGs: COG0073 EMAP domain; InterPro IPR002547:IPR008231; KEGG: npu:Npun_R0138 export-related chaperone CsaA; PFAM: tRNA-binding domain; SPTR: EMAP domain protein; TIGRFAM: Secretion chaperone CsaA. (110 aa)
glkPFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; COGs: COG0837 Glucokinase; InterPro IPR003836; KEGG: ava:Ava_0933 glucokinase; PFAM: Glucokinase; PRIAM: Glucokinase; SPTR: Glucokinase; TIGRFAM: Glucokinase; Belongs to the bacterial glucokinase family. (345 aa)
lipA-2Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (297 aa)
hisA1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; InterPro IPR006062:IPR006063; KEGG: ana:all4506 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: Histidi [...] (257 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
pgiPFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: npu:Npun_F3925 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family. (528 aa)
AFZ32717.1Metallo-beta-lactamase domain containing 2; PFAM: Metallo-beta-lactamase superfamily; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: rno:365627 metallo-beta-lactamase domain containing 2; SPTR: Putative uncharacterized protein Mblac2. (271 aa)
AFZ32719.1NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: amr:AM1_6100 zinc-binding oxidoreductase, putative; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: NADPH:quinone reductase; SPTR: Zinc-binding oxidoreductase, putative. (341 aa)
AFZ32731.1Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR004490; KEGG: npu:Npun_R6128 glycolate oxidase, subunit GlcD; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; TIGRFAM: Glycolate oxidase subunit GlcD. (490 aa)
AFZ32732.1PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: npu:Npun_F0762 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; SPTR: FAD linked oxidase domain protein. (430 aa)
glyQPFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit; COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; HAMAP: Glycyl-tRNA synthetase, class IIc, alpha subunit; InterPro IPR002310; KEGG: ana:all1985 glycyl-tRNA synthetase subunit alpha; PFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit. (297 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
AFZ32761.1PFAM: Phosphorylase superfamily; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845; KEGG: vap:Vapar_2659 adenosylhomocysteine nucleosidase; PFAM: Nucleoside phosphorylase; SPTR: Adenosylhomocysteine nucleosidase. (415 aa)
argJGlutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (484 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (319 aa)
argSarginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR005148:IPR015945:IPR008909:IPR001278; KEGG: npu:Npun_R4006 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; Arginyl tRNA synthetase, class Ic, N-terminal; DALR anticodon binding; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic. (585 aa)
AFZ32801.1Cysteine desulfurase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufSfamily; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192:IPR010970; KEGG: npu:Npun_F4825 SufS subfamily cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Selenocysteine lyase; SPTR: Cysteine desulfurase, SufS subfamily; TIGRFAM: Cysteine desulfurase, SufS; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
AFZ32817.1PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752:IPR003710; KEGG: npu:Npun_F6324 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE. (325 aa)
AFZ32899.1PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; COGs: COG0686 Alanine dehydrogenase; InterPro IPR007886:IPR007698:IPR008141; KEGG: npu:Npun_R3990 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; PRIAM: Alanine dehydrogenase; SPTR: Alanine dehydrogenase; TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; Belongs to the AlaDH/PNT family. (363 aa)
AFZ32900.1KEGG: npu:Npun_R5521 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein. (289 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (495 aa)
AFZ32969.18-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: cyc:PCC7424_2980 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: Aminotransferase, classes I and II superfamily. (426 aa)
pgkPFAM: Phosphoglycerate kinase; COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: ava:Ava_0772 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481:IPR005479:IPR005480:IPR011607:IPR 006275; KEGG: ana:alr3809 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl phosphate synthase, large sub [...] (1105 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (408 aa)
AFZ33105.1TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: naz:Aazo_1129 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. (271 aa)
leuSTIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR015413:IPR013155:IPR002302; KEGG: ana:alr3283 leucyl-tRNA synthetase; PFAM: Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Aminoacyl-tRNA synthetase, class I (M); SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial. (849 aa)
AFZ33115.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (810 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa)
AFZ33155.1TIGRFAM: amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: ana:alr4934 N-acyl-L-amino acid amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: N-acyl-L-amino acid amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase. (426 aa)
AFZ33157.1Glyoxylate reductase; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: bts:Btus_3064 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: Glyoxylate reductase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein. (321 aa)
AFZ33173.1COGs: COG1231 Monoamine oxidase; InterPro IPR002937:IPR006311; KEGG: gvi:gll1123 hypothetical protein; PFAM: Amine oxidase; PRIAM: Monoamine oxidase; SPTR: Gll1123 protein. (540 aa)
AFZ33178.1InterPro IPR006094; KEGG: smd:Smed_4040 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase, N-terminal; SPTR: FAD linked oxidase domain protein. (133 aa)
AFZ33210.1KEGG: amr:AM1_1212 hypothetical protein; SPTR: Putative uncharacterized protein. (307 aa)
AFZ33227.1FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094; KEGG: ava:Ava_1368 FAD linked oxidase-like; PFAM: FAD linked oxidase, N-terminal; SPTR: FAD linked oxidase-like. (450 aa)
AFZ33240.1Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (338 aa)
AFZ33244.1Cyclase family protein; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: rrs:RoseRS_1541 cyclase family protein; PFAM: Putative cyclase; SPTR: Putative cyclase. (264 aa)
AFZ33247.1TIGRFAM: benzoate-CoA ligase family; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR011957; KEGG: amr:AM1_A0246 benzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Benzoate--CoA ligase; SPTR: Benzoate-CoA ligase; TIGRFAM: Benzoate-CoA ligase family. (515 aa)
AFZ33248.1Holo-(acyl-carrier-protein) synthase; TIGRFAM: phosphopantetheine--protein transferase domain; holo-[acyl-carrier-protein] synthase; COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); InterPro IPR008278:IPR004568; KEGG: amr:AM1_A0245 holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-acyl-carrier-protein synthase; TIGRFAM: Phosphopantethiene-protein transferase; Belongs to the P-Pant transferase superfamily. (149 aa)
AFZ33249.1KEGG: amr:AM1_A0244 hypothetical protein; SPTR: Acyl carrier protein. (80 aa)
AFZ33250.1Beta-ketoacyl-acyl-carrier-protein synthase II; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: fre:Franean1_2394 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SPTR: Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (402 aa)
AFZ33251.1Beta-ketoacyl-acyl-carrier-protein synthase II; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: mau:Micau_3496 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SPTR: Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (424 aa)
AFZ33252.1COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: scl:sce8996 methylenetetrahydrofolate reductase (NAD(P)H); PFAM: Methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (313 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (331 aa)
AFZ33294.1TIGRFAM: amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: acd:AOLE_16100 N-alpha-acyl-glutamine aminoacylase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase. (472 aa)
Your Current Organism:
Gloeocapsa sp. PCC7428
NCBI taxonomy Id: 1173026
Other names: Chroococcus sp. Cey un, G. sp. PCC 7428, Gloeocapsa sp. ATCC 29159, Gloeocapsa sp. PCC 7428
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