Your Input: | |
| | AFZ28729.1 | Hypothetical protein; PFAM: Diacylglycerol kinase catalytic domain; PRC-barrel domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; COGs: COG1597 Sphingosine kinase; InterPro IPR007903:IPR001206:IPR005218; KEGG: ava:Ava_4772 putative lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; PRC-barrel; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00147. (534 aa) |
| | folE | PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR020602:IPR001474; KEGG: naz:Aazo_3367 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I. (239 aa) |
| | AFZ28772.1 | Hypothetical protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: npu:Npun_R3791 putative lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Diacylglycerol kinase, catalytic region; TIGRFAM: Conserved hypothetical protein CHP00147. (303 aa) |
| | AFZ28777.1 | Molybdopterin synthase subunit MoaD; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal; COGs: COG1977 Molybdopterin converting factor small subunit; InterPro IPR003749; KEGG: naz:Aazo_2961 thiamineS protein; PFAM: ThiamineS; SPTR: ThiamineS. (91 aa) |
| | AFZ28834.1 | Hypothetical protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: npu:Npun_F2878 putative lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Diacylglycerol kinase, catalytic region; TIGRFAM: Conserved hypothetical protein CHP00147. (287 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (205 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (343 aa) |
| | thiC | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (457 aa) |
| | AFZ28914.1 | PFAM: Inositol monophosphatase family; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase, bacterial; COGs: COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; InterPro IPR000760; KEGG: npu:Npun_F2380 inositol monophosphatase; PFAM: Inositol monophosphatase; SPTR: Inositol monophosphatase. (285 aa) |
| | AFZ28933.1 | PFAM: Prokaryotic diacylglycerol kinase; COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: ana:all0270 diacylglycerol kinase; PFAM: Diacylglycerol kinase, prokaryotic; SPTR: Prokaryotic diacylglycerol kinase. (149 aa) |
| | AFZ28967.1 | PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein; COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR005992:IPR001093; KEGG: ana:alr0051 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; SPTR: IMP dehydrogenase; TIGRFAM: IMP dehydrogenase related 2; manually curated. (387 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (149 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa) |
| | AFZ29131.1 | PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR019468; KEGG: ava:Ava_3410 adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | AFZ29147.1 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: cyc:PCC7424_2757 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (192 aa) |
| | AFZ29296.1 | PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: ana:all2303 dihydroorotase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Dihydroorotase; TIGRFAM: Dihydroorotase multifunctional complex type. (442 aa) |
| | AFZ29298.1 | TIGRFAM: dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: ava:Ava_3650 dihydroorotase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase family, putative; TIGRFAM: Dihydroorotase multifunctional complex type. (420 aa) |
| | AFZ29310.1 | Protein of unknown function UPF0157; PFAM: Uncharacterised protein family (UPF0157); COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: amr:AM1_2289 hypothetical protein; PFAM: Uncharacterised protein family UPF0157; SPTR: Putative uncharacterized protein. (176 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (534 aa) |
| | moaA | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa) |
| | thiE | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (383 aa) |
| | AFZ29354.1 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR003749:IPR010035; KEGG: ana:asr1344 hypothetical protein; PFAM: ThiamineS; SPTR: Asr1344 protein; TIGRFAM: ThiS, thiamine-biosynthesis. (70 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | coaX | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (261 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa) |
| | AFZ29534.1 | Protein of unknown function UPF0157; PFAM: Uncharacterised protein family (UPF0157); COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: acr:Acry_3062 hypothetical protein; PFAM: Uncharacterised protein family UPF0157; SPTR: Putative uncharacterized protein. (175 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (185 aa) |
| | purT | Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (387 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (591 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa) |
| | atpB | ATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (253 aa) |
| | atpE | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa) |
| | atpG | ATP synthase F0 subcomplex B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria. Belongs to the ATPase B chain family. (163 aa) |
| | atpF | ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (185 aa) |
| | atpH | ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (184 aa) |
| | atpA | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (505 aa) |
| | folD | Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (173 aa) |
| | AFZ31288.1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (458 aa) |
| | AFZ31268.1 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (427 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa) |
| | dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (309 aa) |
| | pyrB | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: npu:Npun_F5181 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspar [...] (329 aa) |
| | pyrE-2 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (185 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa) |
| | AFZ31134.1 | PFAM: Protein of unknown function (DUF561); InterPro IPR007570; KEGG: npu:Npun_R5436 hypothetical protein; PFAM: Protein of unknown function DUF561; SPTR: Putative uncharacterized protein. (247 aa) |
| | AFZ31112.1 | Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; COGs: COG2236 phosphoribosyltransferase; KEGG: npu:Npun_R1761 phosphoribosyltransferase; SPTR: Phosphoribosyltransferase. (174 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (392 aa) |
| | lpxA | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (274 aa) |
| | fabZ | 3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (174 aa) |
| | lpxC | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (303 aa) |
| | purC | PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: ana:alr2268 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase. (248 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa) |
| | AFZ30975.1 | MoaD family protein; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal; COGs: COG1977 Molybdopterin converting factor small subunit; InterPro IPR003749:IPR010038; KEGG: npu:Npun_R6259 thiamineS protein; PFAM: ThiamineS; SPTR: Putative uncharacterized protein; TIGRFAM: MoaD, archaeal. (85 aa) |
| | AFZ30952.1 | FAD dependent oxidoreductase; InterPro IPR006076; KEGG: ava:Ava_2844 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: Putative uncharacterized protein. (671 aa) |
| | AFZ30948.1 | PFAM: MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: ava:Ava_4754 molybdopterin synthase subunit MoaE; PFAM: Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin synthase subunit MoaE. (164 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (237 aa) |
| | pyrD | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (387 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (326 aa) |
| | AFZ30841.1 | Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | AFZ30772.1 | PFAM: Inositol monophosphatase family; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: ava:Ava_0983 inositol monophosphatase; PFAM: Inositol monophosphatase; PRIAM: Inositol-phosphate phosphatase; SPTR: Inositol monophosphatase. (288 aa) |
| | thiG | Glycine oxidase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (657 aa) |
| | mobA | Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (217 aa) |
| | AFZ30554.1 | InterPro IPR002218; KEGG: ava:Ava_0151 hypothetical protein; PFAM: Glucose-inhibited division protein A-related; SPTR: Putative uncharacterized protein. (569 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (225 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (89 aa) |
| | moaC | Cyclic pyranopterin monophosphate synthase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (165 aa) |
| | AFZ30430.1 | COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: npu:Npun_R5090 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. (334 aa) |
| | AFZ30408.1 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (772 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR020562:IPR020561:IPR020560:IPR000115; KEGG: ava:Ava_3227 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthe [...] (427 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (495 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (397 aa) |
| | AFZ30194.1 | Hypothetical protein; COGs: COG0763 Lipid A disaccharide synthetase; KEGG: ava:Ava_1699 hypothetical protein; SPTR: Putative uncharacterized protein. (427 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (307 aa) |
| | AFZ29802.1 | 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: AIR carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: ava:Ava_1809 phosphoribosylaminoimidazole carboxylase catalytic subunit; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: Probable phosphoribosylaminoimidazole carboxylase catalytic subunit. (268 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (193 aa) |
| | AFZ29814.1 | PFAM: Cytidylyltransferase family; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: ava:Ava_1818 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. (289 aa) |
| | AFZ29838.1 | Riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR002606:IPR015864:IPR015865; KEGG: naz:Aazo_3260 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Belongs to the ribF family. (336 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (349 aa) |
| | plsY | Acyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (227 aa) |
| | AFZ30110.1 | Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: tra:Trad_0511 metallophosphoesterase; PFAM: Metallophosphoesterase; SPTR: Ser/Thr protein phosphatase family protein. (302 aa) |
| | AFZ30122.1 | Hypothetical protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: ava:Ava_4772 putative lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Diacylglycerol kinase, catalytic region; TIGRFAM: Conserved hypothetical protein CHP00147. (327 aa) |
| | panC/cmk | Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. (526 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728:IPR010918:IPR004733; KEGG: naz:Aazo_3150 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: Phosphoribosylformylglyci [...] (342 aa) |
| | AFZ30173.1 | TIGRFAM: deoxycytidine triphosphate deaminase; COGs: COG0717 Deoxycytidine deaminase; InterPro IPR011962; KEGG: npu:Npun_F2524 deoxycytidine triphosphate deaminase; PRIAM: dCTP deaminase; SPTR: Deoxycytidine triphosphate deaminase; TIGRFAM: Deoxycytidine triphosphate deaminase; manually curated. (197 aa) |
| | AFZ30175.1 | PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase, methanogen type; COGs: COG0207 Thymidylate synthase; InterPro IPR000398; KEGG: cyh:Cyan8802_1276 thymidylate synthase; PFAM: Thymidylate synthase; SPTR: Thymidylate synthase. (498 aa) |
| | atpG-2 | ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa) |
| | atpD | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (482 aa) |
| | atpC | ATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa) |
| | AFZ33247.1 | TIGRFAM: benzoate-CoA ligase family; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR011957; KEGG: amr:AM1_A0246 benzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Benzoate--CoA ligase; SPTR: Benzoate-CoA ligase; TIGRFAM: Benzoate-CoA ligase family. (515 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (208 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (338 aa) |
| | purH | IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: Bifunctional purine biosynthesis protein purH; InterPro IPR013982:IPR011607:IPR002695; KEGG: npu:Npun_R6316 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; MGS-like; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformyla [...] (514 aa) |
| | AFZ33104.1 | Hypothetical protein; TIGRFAM: PPOX class probable FMN-dependent enzyme, alr4036 family; COGs: COG5135 conserved hypothetical protein; KEGG: ana:alr4036 hypothetical protein; SPTR: Pyridoxamine 5'-phosphate oxidase-related, FMN-binding protein. (189 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (408 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481:IPR005479:IPR005480:IPR011607:IPR 006275; KEGG: ana:alr3809 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl phosphate synthase, large sub [...] (1105 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (223 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) |
| | AFZ32790.1 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638:IPR004393; KEGG: ava:Ava_3136 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide pyrophosphorylase (Carboxylating); TIGRFAM: Nicotinate-nucleotide pyrophosphoryl [...] (288 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (319 aa) |
| | AFZ32783.1 | Hypothetical protein; COGs: COG0563 Adenylate kinase and related kinase; KEGG: sth:STH2305 hypothetical protein; SPTR: Putative uncharacterized protein. (174 aa) |
| | AFZ32681.1 | Dihydropyrimidinase; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase; dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR011778; KEGG: cti:RALTA_A2550 dihydropyrimidinase; PFAM: Amidohydrolase 1; PRIAM: Dihydropyrimidinase; SPTR: Phenylhydantoinase; TIGRFAM: D-hydantoinase. (482 aa) |
| | glmU | Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa) |
| | AFZ32552.1 | Hypothetical protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family; methylglyoxal synthase; COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: ter:Tery_0827 methylglyoxal synthase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Methylglyoxal synthase; TIGRFAM: Conserved hypothetical protein CHP00147. (430 aa) |
| | AFZ32534.1 | Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: amr:AM1_5183 Ser/Thr protein phosphatase family protein, putative; PFAM: Metallophosphoesterase; SPTR: Ser/Thr protein phosphatase family protein, putative. (287 aa) |
| | purN | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (222 aa) |
| | AFZ32492.1 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (334 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (626 aa) |
| | AFZ32378.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (172 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (407 aa) |
| | AFZ32322.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (559 aa) |
| | AFZ32320.1 | Diguanylate cyclase with PAS/PAC and Chase2 sensors; PFAM: CHASE2 domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG4252 transmembrane sensor domain; InterPro IPR000014:IPR000160:IPR007890:IPR013656; KEGG: ava:Ava_0638 diguanylate cyclase; PFAM: CHASE2; PAS fold-4; Diguanylate cyclase, predicted; PRIAM: Diguanylate kinase; SMART: Diguanylate cyclase, predicted; PAS; SPTR: Putative diguanylate cyclase (GGDEF domain) with PAS/PAC and Chase2 sensors; TIGRFAM: Diguanylate cyclase, predicted; PAS. (733 aa) |
| | AFZ32211.1 | Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: putative HD superfamily hydrolase of NAD metabolism; uncharacterized domain HDIG; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006675:IPR003607:IPR006674; KEGG: tel:tll1325 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00488; HDIG. (211 aa) |
| | carA | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: ana:alr1155 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl phosphate synthase, small subunit; Belong [...] (387 aa) |
| | AFZ32093.1 | Hypothetical protein; PFAM: Di-glucose binding within endoplasmic reticulum; KEGG: gvi:glr0462 hypothetical protein; SPTR: Glr0462 protein. (837 aa) |
| | nadD-2 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (216 aa) |
| | thiL | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (336 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa) |
| | AFZ31982.1 | TIGRFAM: uracil phosphoribosyltransferase; COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765; KEGG: npu:Npun_F4226 uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: Uracil phosphoribosyl transferase; Belongs to the UPRTase family. (216 aa) |
| | AFZ31939.1 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR004552:IPR002123; KEGG: ava:Ava_2731 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferases; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (212 aa) |
| | plsX | Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (348 aa) |
| | AFZ31931.1 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: npu:Npun_F0093 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. (249 aa) |
| | gpsA | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; InterPro IPR011128:IPR006109; KEGG: npu:Npun_F0995 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (322 aa) |
| | AFZ31855.1 | CTP synthase; PFAM: Glutamine amidotransferase class-I; COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR000991; KEGG: esa:ESA_02182 hypothetical protein; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: Putative uncharacterized protein. (238 aa) |
| | AFZ31804.1 | Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: npu:Npun_R0153 metallophosphoesterase; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase. (278 aa) |
| | AFZ31782.1 | PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; KEGG: ava:Ava_0169 phosphoribulokinase; SPTR: Phosphoribulokinase. (318 aa) |
| | AFZ31771.1 | Hypothetical protein; COGs: COG0563 Adenylate kinase and related kinase; KEGG: npu:Npun_BF100 hypothetical protein; SPTR: Putative uncharacterized protein. (182 aa) |
| | AFZ31762.1 | PFAM: FRG domain; InterPro IPR014966; KEGG: geo:Geob_0960 FRG domain protein; PFAM: FRG domain; SPTR: FRG domain protein. (255 aa) |
| | AFZ31746.1 | Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: npu:Npun_F6414 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl atta [...] (441 aa) |
| | AFZ31734.1 | PFAM: Acyltransferase; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: ana:all4871 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: All4871 protein. (270 aa) |
| | pyrE-3 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (477 aa) |
| | nadK-2 | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (362 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (441 aa) |
| | AFZ31615.1 | Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: cyt:cce_0180 cardiolipin synthase-like protein; PFAM: Phospholipase D/Transphosphatidylase; SPTR: Cardiolipin synthetase. (452 aa) |
| | AFZ31556.1 | Glyoxalase/bleomycin resistance protein/dioxygenase; InterPro IPR004360; KEGG: mxa:MXAN_0496 glyoxalase family protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxylase family protein. (128 aa) |
| | AFZ31454.1 | KEGG: npu:Npun_R4714 hypothetical protein; SPTR: Putative uncharacterized protein. (423 aa) |
| | AFZ31434.1 | Competence/damage-inducible protein cinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR008136:IPR001453; KEGG: ava:Ava_2078 competence damage-inducible protein A; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, [...] (418 aa) |
| | AFZ31307.1 | PFAM: DRTGG domain; CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0857 BioD-like N-terminal domain of phosphotransacetylase; InterPro IPR010766; KEGG: ava:Ava_1998 DRTGG; PFAM: DRTGG; SPTR: DRTGG. (370 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa) |
| | AFZ28633.1 | Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (172 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (377 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) |
