STRINGSTRING
rsgA rsgA AFZ29043.1 AFZ29043.1 AFZ29152.1 AFZ29152.1 efp efp ruvA ruvA AFZ29441.1 AFZ29441.1 lysS lysS AFZ29469.1 AFZ29469.1 recO recO infA infA rpsQ rpsQ rplB rplB asnS asnS AFZ29793.1 AFZ29793.1 AFZ30055.1 AFZ30055.1 nusA nusA aspS aspS AFZ30397.1 AFZ30397.1 AFZ30547.1 AFZ30547.1 AFZ30605.1 AFZ30605.1 pnp pnp AFZ30980.1 AFZ30980.1 AFZ31025.1 AFZ31025.1 AFZ31259.1 AFZ31259.1 pheT pheT AFZ31272.1 AFZ31272.1 AFZ31412.1 AFZ31412.1 recG recG rpsL rpsL rimO rimO ligA ligA AFZ32565.1 AFZ32565.1 AFZ32693.1 AFZ32693.1 AFZ32699.1 AFZ32699.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rsgARibosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (362 aa)
AFZ29043.1PFAM: S1 RNA binding domain; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: npu:Npun_F0856 RNA-binding S1 domain-containing protein; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: RNA binding S1 domain protein; manually curated. (299 aa)
AFZ29152.1PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; COGs: COG2183 Transcriptional accessory protein; InterPro IPR018974:IPR003029:IPR006641; KEGG: npu:Npun_R5425 RNA-binding S1 domain-containing protein; PFAM: Tex-like protein, N-terminal; Ribosomal protein S1, RNA binding domain; SMART: Resolvase, RNase H-like fold; SPTR: RNA binding S1 domain protein. (730 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (208 aa)
AFZ29441.1PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: npu:Npun_F1842 single-stranded DNA-binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding. (119 aa)
lysSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; COGs: COG1190 Lysyl-tRNA synthetase (class II); HAMAP: Lysyl-tRNA synthetase, class II; InterPro IPR002313:IPR004365:IPR004364; KEGG: ava:Ava_3150 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (575 aa)
AFZ29469.1Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: ava:Ava_4829 ABC transporter-like; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Glycerol-3-phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter-like protein. (365 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (319 aa)
infABacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (74 aa)
rpsQSSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (83 aa)
rplBLSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (287 aa)
asnSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase; COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase; InterPro IPR004365:IPR004364:IPR004522; KEGG: npu:Npun_R0874 asparaginyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb. (462 aa)
AFZ29793.1PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR013216:IPR001566; KEGG: ana:alr3654 hypothetical protein; PFAM: Deoxyribonuclease/rho motif-related TRAM; Methyltransferase type 11; SPTR: 23S rRNA methyltransferase/RumA; TIGRFAM: 23S rRNA methyltransferase/RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (466 aa)
AFZ30055.1Ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family; COGs: COG1530 Ribonuclease G and E; InterPro IPR004659:IPR003029:IPR019307; KEGG: ana:alr4331 ribonuclease E; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA binding domain; PRIAM: Ribonuclease E; SPTR: Ribonuclease E; TIGRFAM: Ribonuclease E/G. (674 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (428 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa)
AFZ30397.1Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: amr:AM1_1478 sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Glycerol-3-phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Sugar ABC transporter, ATP-binding protein. (366 aa)
AFZ30547.1Protein of unknown function DUF107; PFAM: NfeD-like; COGs: COG1585 Membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: npu:Npun_F6579 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative uncharacterized protein. (141 aa)
AFZ30605.1SSU ribosomal protein S1P; PFAM: S1 RNA binding domain; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: ana:all0136 30S ribosomal protein S1; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: 30S ribosomal protein S1. (330 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (719 aa)
AFZ30980.1Polyamine-transporting ATPase; PFAM: ABC transporter; TOBE domain; TIGRFAM: spermidine/putrescine ABC transporter ATP-binding subunit; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: cbe:Cbei_4940 spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Spermidine/putrescine import ATP-binding protein PotA. (358 aa)
AFZ31025.1Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: ava:Ava_2050 ABC transporter-like; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Glycerol-3-phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter-like; Belongs to the ABC transporter superfamily. (437 aa)
AFZ31259.1PFAM: Single-strand binding protein family; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: ava:Ava_2046 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding. (180 aa)
pheTphenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: npu:Npun_F1087 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synth [...] (814 aa)
AFZ31272.1Exoribonuclease II; PFAM: RNB domain; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: ava:Ava_1322 ribonuclease II; PFAM: Ribonuclease II/R; PRIAM: Exoribonuclease II; SPTR: Ribonuclease II. (685 aa)
AFZ31412.1PFAM: Ribonuclease B OB domain; RNB domain; S1 RNA binding domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases; COGs: COG0557 Exoribonuclease R; InterProIPR004476:IPR013223:IPR001900:IPR003029:IPR 011129; KEGG: ava:Ava_0549 3'-5' exoribonuclease, VacB and RNase II; PFAM: Ribonuclease II/R; Ribonuclease B, N-terminal OB domain; Ribosomal protein S1, RNA binding domain; SPTR: 3'-5' exoribonuclease, VacB and RNase II; TIGRFAM: Ribonuclease II/ribonuclease R, bacteria; Belongs to the RNR ribonuclease family. (793 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (833 aa)
rpsLSSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
rimOSSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (439 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (678 aa)
AFZ32565.1Export-related chaperone CsaA; PFAM: Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; export-related chaperone CsaA; COGs: COG0073 EMAP domain; InterPro IPR002547:IPR008231; KEGG: npu:Npun_R0138 export-related chaperone CsaA; PFAM: tRNA-binding domain; SPTR: EMAP domain protein; TIGRFAM: Secretion chaperone CsaA. (110 aa)
AFZ32693.1Polyamine-transporting ATPase; PFAM: ABC transporter; TOBE domain; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: mrd:Mrad2831_1247 ABC transporter related; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related. (381 aa)
AFZ32699.1Glycerol-3-phosphate-transporting ATPase; PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: oan:Oant_3851 ABC transporter related; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Glycerol-3-phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: TOBE domain family. (369 aa)
Your Current Organism:
Gloeocapsa sp. PCC7428
NCBI taxonomy Id: 1173026
Other names: Chroococcus sp. Cey un, G. sp. PCC 7428, Gloeocapsa sp. ATCC 29159, Gloeocapsa sp. PCC 7428
Server load: low (16%) [HD]