STRINGSTRING
AFZ28644.1 AFZ28644.1 AFZ28759.1 AFZ28759.1 AFZ28812.1 AFZ28812.1 AFZ28819.1 AFZ28819.1 AFZ28829.1 AFZ28829.1 AFZ28851.1 AFZ28851.1 AFZ28877.1 AFZ28877.1 AFZ28926.1 AFZ28926.1 AFZ29004.1 AFZ29004.1 AFZ29060.1 AFZ29060.1 AFZ29136.1 AFZ29136.1 AFZ29313.1 AFZ29313.1 AFZ29350.1 AFZ29350.1 AFZ29362.1 AFZ29362.1 AFZ29366.1 AFZ29366.1 AFZ29370.1 AFZ29370.1 AFZ29459.1 AFZ29459.1 AFZ29512.1 AFZ29512.1 AFZ33124.1 AFZ33124.1 mutL mutL AFZ29688.1 AFZ29688.1 AFZ29689.1 AFZ29689.1 AFZ29691.1 AFZ29691.1 AFZ29694.1 AFZ29694.1 AFZ29696.1 AFZ29696.1 AFZ29732.1 AFZ29732.1 AFZ29791.1 AFZ29791.1 AFZ29912.1 AFZ29912.1 AFZ30005.1 AFZ30005.1 AFZ30575.1 AFZ30575.1 AFZ33180.1 AFZ33180.1 AFZ30618.1 AFZ30618.1 AFZ30619.1 AFZ30619.1 AFZ30623.1 AFZ30623.1 AFZ30627.1 AFZ30627.1 AFZ30628.1 AFZ30628.1 AFZ30629.1 AFZ30629.1 AFZ30630.1 AFZ30630.1 AFZ30631.1 AFZ30631.1 AFZ30644.1 AFZ30644.1 AFZ30724.1 AFZ30724.1 AFZ30726.1 AFZ30726.1 AFZ30741.1 AFZ30741.1 AFZ30826.1 AFZ30826.1 AFZ30831.1 AFZ30831.1 AFZ30927.1 AFZ30927.1 AFZ30930.1 AFZ30930.1 AFZ30932.1 AFZ30932.1 AFZ31030.1 AFZ31030.1 AFZ31062.1 AFZ31062.1 AFZ31087.1 AFZ31087.1 AFZ31199.1 AFZ31199.1 AFZ31201.1 AFZ31201.1 AFZ31202.1 AFZ31202.1 AFZ31248.1 AFZ31248.1 AFZ31249.1 AFZ31249.1 AFZ31344.1 AFZ31344.1 AFZ31349.1 AFZ31349.1 AFZ31351.1 AFZ31351.1 AFZ31388.1 AFZ31388.1 AFZ31481.1 AFZ31481.1 AFZ31527.1 AFZ31527.1 AFZ31560.1 AFZ31560.1 AFZ31582.1 AFZ31582.1 AFZ31584.1 AFZ31584.1 AFZ31863.1 AFZ31863.1 AFZ31887.1 AFZ31887.1 AFZ31949.1 AFZ31949.1 AFZ31980.1 AFZ31980.1 AFZ32081.1 AFZ32081.1 AFZ32082.1 AFZ32082.1 AFZ32142.1 AFZ32142.1 AFZ32329.1 AFZ32329.1 AFZ32338.1 AFZ32338.1 AFZ32339.1 AFZ32339.1 AFZ32359.1 AFZ32359.1 AFZ32384.1 AFZ32384.1 AFZ32393.1 AFZ32393.1 AFZ32468.1 AFZ32468.1 AFZ32578.1 AFZ32578.1 AFZ32579.1 AFZ32579.1 AFZ32581.1 AFZ32581.1 AFZ32582.1 AFZ32582.1 AFZ32590.1 AFZ32590.1 gyrB gyrB AFZ32876.1 AFZ32876.1 AFZ33008.1 AFZ33008.1 AFZ33020.1 AFZ33020.1 sasA sasA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFZ28644.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661:IPR003594; KEGG: ava:Ava_3850 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Perip [...] (375 aa)
AFZ28759.1Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: npu:Npun_F1439 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, di [...] (469 aa)
AFZ28812.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR001610; KEGG: npu:Npun_F6350 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; PAS fold-3; Signal transduction response regulat [...] (759 aa)
AFZ28819.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: npu:Npun_R2421 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Periplasmic Sensor Signal Transduction Histidine Kinase. (401 aa)
AFZ28829.1Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: ana:all4726 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...] (370 aa)
AFZ28851.1Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: npu:Npun_R1236 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, di [...] (656 aa)
AFZ28877.1CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789; KEGG: npu:Npun_F5640 CheA signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction histidine kinase, subgroup, homodimeric; C [...] (938 aa)
AFZ28926.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_F1330 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase. (407 aa)
AFZ29004.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594:IPR001789; KEGG: ava:Ava_1086 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimer [...] (902 aa)
AFZ29060.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: npu:Npun_F0839 response regulator receiver sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction h [...] (366 aa)
AFZ29136.1PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Predicted domain in sensory proteins (DUF2308); COGs: COG4250 sensor protein/domain; InterPro IPR003018:IPR003661:IPR003594; KEGG: npu:Npun_R5149 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: GAF sensor sig [...] (695 aa)
AFZ29313.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: npu:Npun_F1000 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: GAF sensor signal transduction histidine kinase. (650 aa)
AFZ29350.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG5002 Signal transduction histidine kinase; InterProIPR013656:IPR003661:IPR003594:IPR003018:IPR 000014; KEGG: amr:AM1_0224 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dime [...] (729 aa)
AFZ29362.1PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR003661:IPR003594:IPR001789:IPR 013655:IPR003018:IPR000014:IPR001610; KEGG: ava:Ava_1086 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; Signal transduction response regulator, receiver domain; PAS fold-3; [...] (1322 aa)
AFZ29366.1Multi-sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR007891:IPR003660:IPR003661:IPR003594; KEGG: amr:AM1_1468 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; CHASE3; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, di [...] (509 aa)
AFZ29370.1PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Predicted domain in sensory proteins (DUF2308); COGs: COG4250 sensor protein/domain; InterPro IPR003018:IPR003661:IPR003594; KEGG: cyn:Cyan7425_3573 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: GAF Sensor [...] (645 aa)
AFZ29459.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ava:Ava_3159 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Periplasmi [...] (465 aa)
AFZ29512.1Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: chl:Chy400_2625 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, d [...] (479 aa)
AFZ33124.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: npu:Npun_R1550 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: GAF sensor signal transduction histidine kinase. (570 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (572 aa)
AFZ29688.1PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR013655:IPR003661:IPR003594:IPR001610:IPR 000014; KEGG: ava:Ava_1559 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; [...] (724 aa)
AFZ29689.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; Bacterial signalling protein N terminal repeat; TIGRFAM: PAS domain S-box; COGs: COG3300 MHYT domain (predicted integral membrane sensor domain); InterProIPR005330:IPR013767:IPR013656:IPR003661:IPR 003594:IPR000014; KEGG: cyc:PCC7424_1419 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; MHYT; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phospho [...] (759 aa)
AFZ29691.1Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR013656:IPR 003018:IPR003661:IPR003594:IPR000014:IPR001610; KEGG: npu:Npun_F5679 multi-sensor hybrid multi-kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold-3; PAS fold; PAS fold-4; GAF; Signal trans [...] (1220 aa)
AFZ29694.1PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003661:IPR003594:IPR000014:IPR 001610; KEGG: cyn:Cyan7425_3118 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinas [...] (428 aa)
AFZ29696.1Putative CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR004105:IPR003594:IPR002545:IPR001789; KEGG: ana:all0926 two-component hybrid sensor and regulator; PFAM: Signal transduction response regulator, receiver domain; CheW-like protein; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup, homodimeric; SMART: Si [...] (1030 aa)
AFZ29732.1Multi-sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: npu:Npun_R3716 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal tr [...] (653 aa)
AFZ29791.1COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); KEGG: naz:Aazo_3653 putative anti-sigma regulatory factor serine/threonine protein kinase; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase. (149 aa)
AFZ29912.1Hypothetical protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; KEGG: ava:Ava_B0306 hypothetical protein; SPTR: Putative uncharacterized protein. (608 aa)
AFZ30005.1CheA signal transduction histidine kinase; PFAM: CheW-like domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR001789:IPR 004105; KEGG: cyt:cce_4190 CheA-like two-component hybrid sensor and regulator; PFAM: Signal transduction response regulator, receiver domain; CheW-like protein; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphot [...] (1077 aa)
AFZ30575.1PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013655:IPR013656; KEGG: npu:Npun_R3572 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold-4; Signal transduction response regulat [...] (1165 aa)
AFZ33180.1PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013655:IPR000014:IPR001610; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; PAS fold-4; PAS fold-3; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal tra [...] (1217 aa)
AFZ30618.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR007891:IPR013655:IPR013656; KEGG: cyn:Cyan7425_3017 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; CHASE3; PAS fold-3; GAF; PAS fold-4; Signal transduction histidine kinase, subgro [...] (1361 aa)
AFZ30619.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR001789:IPR003661:IPR003594:IPR000014; KEGG: gvi:gll1533 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver [...] (504 aa)
AFZ30623.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR000014:IPR003018:IPR003661:IPR 003594:IPR013767; KEGG: npu:Npun_R6464 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; GAF; SMART: ATPase-like, ATP-bi [...] (814 aa)
AFZ30627.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013767:IPR013655:IPR013656; KEGG: npu:Npun_R3572 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold; PAS fold-4; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response [...] (1764 aa)
AFZ30628.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013655:IPR013656; KEGG: cyn:Cyan7425_1795 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; PAS fold-4; Signal transduction response regulator, receiver domain; [...] (1786 aa)
AFZ30629.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR001789:IPR 000014:IPR001610:IPR013656:IPR013655; KEGG: cyc:PCC7424_1976 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver doma [...] (1608 aa)
AFZ30630.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR000014:IPR001610:IPR003661:IPR 003594:IPR001789:IPR013655; KEGG: npu:Npun_R3572 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase- [...] (834 aa)
AFZ30631.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR013656:IPR013655; KEGG: npu:Npun_DR038 putative PAS/PAC sensor protein; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; Signal transduction response regulator, receiver domain; PAS fold-3; GAF; SMART: AT [...] (1146 aa)
AFZ30644.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013767; KEGG: npu:Npun_R3083 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain [...] (705 aa)
AFZ30724.1Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR003018:IPR003661:IPR 003594:IPR000014:IPR001610; KEGG: tel:tll1282 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; Signal transductio [...] (864 aa)
AFZ30726.1Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; Bacterial signalling protein N terminal repeat; TIGRFAM: PAS domain S-box; COGs: COG3300 MHYT domain (predicted integral membrane sensor domain); InterProIPR005330:IPR013767:IPR003018:IPR003661:IPR 003594:IPR000014; KEGG: cyn:Cyan7425_4421 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; MHYT; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosp [...] (806 aa)
AFZ30741.1Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: cyn:Cyan7425_1565 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP li [...] (485 aa)
AFZ30826.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG5002 Signal transduction histidine kinase; InterProIPR013655:IPR013656:IPR003661:IPR003594:IPR 000014:IPR001610; KEGG: cyt:cce_3558 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidin [...] (1051 aa)
AFZ30831.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003594; KEGG: dbr:Deba_0034 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; SPTR: Putative Histidine kinase. (489 aa)
AFZ30927.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CHASE domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR006189:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: npu:Npun_F6350 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; CHASE; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine ki [...] (742 aa)
AFZ30930.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003661:IPR003594:IPR 000014:IPR001610; KEGG: npu:Npun_F3541 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; S [...] (524 aa)
AFZ30932.1PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR007891:IPR003660:IPR003018:IPR003661:IPR 003594:IPR001789; KEGG: npu:Npun_R2375 multi-sensor hybrid histidine kinase; PFAM: CHASE3; HAMP linker domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bindi [...] (1199 aa)
AFZ31030.1CBS sensor hybrid histidine kinase; PFAM: CBS domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR000644:IPR003661:IPR003594:IPR001789; KEGG: naz:Aazo_5073 CBS sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Cystathionine beta-synthase, core; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-b [...] (1062 aa)
AFZ31062.1Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ava:Ava_2239 adenylate/guanylate cyclase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor doma [...] (1124 aa)
AFZ31087.1PFAM: His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661; KEGG: ava:Ava_1486 histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase. (304 aa)
AFZ31199.1PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR001789:IPR013656:IPR003661:IPR 003594:IPR001610; KEGG: npu:Npun_R2901 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold-4; Signal transduction histidine kinase, subgr [...] (642 aa)
AFZ31201.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR000014:IPR001789:IPR013655:IPR003018:IPR 003661:IPR003594:IPR001610; KEGG: npu:Npun_R2903 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold-3; GAF; [...] (694 aa)
AFZ31202.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 008207; KEGG: ana:all2875 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: A [...] (1079 aa)
AFZ31248.1Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003018:IPR013655:IPR013656:IPR 013767:IPR003661:IPR003594:IPR001789:IPR001610; KEGG: cyn:Cyan7425_4608 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; PAS fold-3; GAF; PAS fold-4; PA [...] (1994 aa)
AFZ31249.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: cyn:Cyan7425_4611 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-b [...] (1010 aa)
AFZ31344.1PFAM: HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004010:IPR003660:IPR003661:IPR003594:IPR 001789; KEGG: ana:alr4878 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; Cache; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Sign [...] (925 aa)
AFZ31349.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_R2485 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase. (456 aa)
AFZ31351.1PFAM: His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661; KEGG: ava:Ava_0501 histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine Kinase. (498 aa)
AFZ31388.1ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. (657 aa)
AFZ31481.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR013655:IPR 013656:IPR003018:IPR003661:IPR003594:IPR001610; KEGG: npu:Npun_F5092 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; Signal transduction response regulator, receiver domain; PAS fold; PAS fold-4; GAF; Signal transduction histidine kinase, subgroup 1, dime [...] (1208 aa)
AFZ31527.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: naz:Aazo_2740 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine Kinase. (427 aa)
AFZ31560.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: npu:Npun_R3591 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, su [...] (591 aa)
AFZ31582.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: cyn:Cyan7425_4616 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; Signal transduction hi [...] (531 aa)
AFZ31584.1Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Phytochrome region; His Kinase A (phosphoacceptor) domain; PAS fold; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR013654:IPR003018:IPR013515:IPR003661:IPR 003594; KEGG: ava:Ava_1003 multi-sensor signal transduction histidine kinase; PFAM: PAS fold-2; GAF; Phytochrome, central region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART [...] (750 aa)
AFZ31863.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_R4028 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Two-component sensor histidine kinase. (445 aa)
AFZ31887.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: npu:Npun_F2781 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: GAF sensor signal transduction histidine kinase. (637 aa)
AFZ31949.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ava:Ava_3865 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Periplasmi [...] (425 aa)
AFZ31980.1GAF sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594:IPR001789; KEGG: ana:alr3120 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidi [...] (733 aa)
AFZ32081.1COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); KEGG: npu:Npun_F1684 putative anti-sigma regulatory factor, serine/threonine protein kinase; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase. (140 aa)
AFZ32082.1PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003018:IPR001610:IPR003661:IPR 003594:IPR001789:IPR008207:IPR007891:IPR013767:IPR013656; KEGG: ava:Ava_1564 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; CHASE3; GAF; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain [...] (1873 aa)
AFZ32142.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR000014:IPR003018:IPR001610:IPR003661:IPR 003594:IPR001789:IPR013656:IPR013655:IPR013767; KEGG: npu:Npun_F5092 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; GAF; PAS fold-4; PAS fold; Signal transduction resp [...] (1795 aa)
AFZ32329.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013767; KEGG: npu:Npun_F6350 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPa [...] (762 aa)
AFZ32338.1PFAM: Histidine kinase; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003594:IPR 013656:IPR013655:IPR011495; KEGG: cyn:Cyan7425_5451 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; GAF; PAS fold-4; PAS fold-3; ATPase-like, ATP-binding domain; SMART: GAF; PAS; PAC motif; ATPase-like, ATP-binding domain; SPTR: PAS fold family; TIGRFAM: PAS. (870 aa)
AFZ32339.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003661:IPR 003594:IPR013767; KEGG: ava:Ava_4326 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMA [...] (521 aa)
AFZ32359.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR007891:IPR013767:IPR013655; KEGG: ana:alr1968 two-component hybrid sensor and regulator; PFAM: CHASE3; PAS fold; PAS fold-3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; Sig [...] (836 aa)
AFZ32384.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013767:IPR013656; KEGG: npu:Npun_R4748 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold; PAS fold-4; Signal transduction response regulator, receiver do [...] (958 aa)
AFZ32393.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003594; KEGG: npu:Npun_R2272 multi-sensor signal transduction multi-kinase; PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Multi-sensor signal transduction multi-kinase. (327 aa)
AFZ32468.1PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013767; KEGG: ana:all0182 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; S [...] (574 aa)
AFZ32578.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; Putative sugar diacid recognition; MASE1; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594:IPR007895; KEGG: cyt:cce_0164 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; MASE1; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup [...] (921 aa)
AFZ32579.1Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003018:IPR003661:IPR003594; KEGG: cyc:PCC7424_5136 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regula [...] (747 aa)
AFZ32581.1Multi-sensor signal transduction histidine kinase; PFAM: Cache domain; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR003660:IPR001610:IPR003661:IPR003594:IPR 013655:IPR000014; KEGG: cyh:Cyan8802_4414 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phos [...] (745 aa)
AFZ32582.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: npu:Npun_R3825 hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal [...] (615 aa)
AFZ32590.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR003660; KEGG: bid:Bind_2997 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/pho [...] (500 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (646 aa)
AFZ32876.1PFAM: CHASE2 domain; COGs: COG4252 transmembrane sensor domain; InterPro IPR007890:IPR003594; KEGG: mar:MAE_41020 sensor protein; PFAM: CHASE2; ATPase-like, ATP-binding domain; SPTR: Putative uncharacterized protein. (626 aa)
AFZ33008.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: amr:AM1_5539 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: ATPase, histidine kinase-, D [...] (442 aa)
AFZ33020.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR001789:IPR 000014:IPR001610:IPR013656:IPR013655:IPR013767; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold-4; [...] (1674 aa)
sasAHistidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (387 aa)
Your Current Organism:
Gloeocapsa sp. PCC7428
NCBI taxonomy Id: 1173026
Other names: Chroococcus sp. Cey un, G. sp. PCC 7428, Gloeocapsa sp. ATCC 29159, Gloeocapsa sp. PCC 7428
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.