STRINGSTRING
fixB fixB fixA fixA nrdG nrdG ESE88221.1 ESE88221.1 ESE87547.1 ESE87547.1 ESE87548.1 ESE87548.1 ESE87615.1 ESE87615.1 ESE87616.1 ESE87616.1 ESE87617.1 ESE87617.1 ESE87618.1 ESE87618.1 napA napA napF napF ESE87349.1 ESE87349.1 nuoN nuoN ESE87381.1 ESE87381.1 ESE87382.1 ESE87382.1 nuoK nuoK ESE87384.1 ESE87384.1 ESE87387.1 ESE87387.1 ESE87388.1 ESE87388.1 ESE87389.1 ESE87389.1 nuoC nuoC nuoB nuoB nuoA nuoA ESE87264.1 ESE87264.1 rsxE rsxE rsxG rsxG rnfD rnfD ESE86985.1 ESE86985.1 msrQ msrQ ESE86648.1 ESE86648.1 ESE86469.1 ESE86469.1 ESE86471.1 ESE86471.1 ESE86481.1 ESE86481.1 ESE86204.1 ESE86204.1 bisC bisC ESE85808.1 ESE85808.1 ESE85942.1 ESE85942.1 ESE85944.1 ESE85944.1 ESE85945.1 ESE85945.1 dld dld ESE85308.1 ESE85308.1 ESE85310.1 ESE85310.1 norV norV ESE85191.1 ESE85191.1 ESE85194.1 ESE85194.1 hycE hycE hycD hycD ESE85198.1 ESE85198.1 ESE85199.1 ESE85199.1 ESE84769.1 ESE84769.1 azoR azoR ESE84781.1 ESE84781.1 ESE84850.1 ESE84850.1 ESE84872.1 ESE84872.1 ESE84873.1 ESE84873.1 ESE84874.1 ESE84874.1 ESE84878.1 ESE84878.1 ESE84879.1 ESE84879.1 ESE84912.1 ESE84912.1 ESE84913.1 ESE84913.1 ESE84915.1 ESE84915.1 ESE84259.1 ESE84259.1 ESE83211.1 ESE83211.1 ESE83213.1 ESE83213.1 ESE83221.1 ESE83221.1 ESE82731.1 ESE82731.1 ESE82823.1 ESE82823.1 grxA grxA hemG hemG ESE82128.1 ESE82128.1 sdhC sdhC sdhA sdhA sdhB sdhB ESE82184.1 ESE82184.1 ESE82185.1 ESE82185.1 ESE82186.1 ESE82186.1 ESE81939.1 ESE81939.1 rsxB rsxB rsxA rsxA ESE81979.1 ESE81979.1 ESE81783.1 ESE81783.1 ESE81784.1 ESE81784.1 ESE81786.1 ESE81786.1 dsbB dsbB ESE81607.1 ESE81607.1 ESE81608.1 ESE81608.1 ESE81612.1 ESE81612.1 ESE81613.1 ESE81613.1 ESE81614.1 ESE81614.1 dipZ dipZ ESE81392.1 ESE81392.1 ESE81393.1 ESE81393.1 ESE81013.1 ESE81013.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fixBElectron transfer flavoprotein FixB; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (314 aa)
fixAElectron transfer flavoprotein FixA; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (257 aa)
nrdGAnaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa)
ESE88221.1COG3783 Soluble cytochrome b562. (128 aa)
ESE87547.1COG1271 Cytochrome bd-type quinol oxidase, subunit 1. (467 aa)
ESE87548.1COG1294 Cytochrome bd-type quinol oxidase, subunit 2. (336 aa)
ESE87615.1COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4. (109 aa)
ESE87616.1COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3. (204 aa)
ESE87617.1COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family. (663 aa)
ESE87618.1COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2. (318 aa)
napANitrate reductase catalytic subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)
napFFerredoxin-type protein; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. (171 aa)
ESE87349.12Fe-2S ferredoxin YfaE; COG0633 Ferredoxin. (84 aa)
nuoNNADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
ESE87381.1COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M). (509 aa)
ESE87382.1COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit. (613 aa)
nuoKNADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
ESE87384.1NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
ESE87387.1NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (908 aa)
ESE87388.1NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa)
ESE87389.1COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. (166 aa)
nuoCBifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (600 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
nuoANADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
ESE87264.1COG2864 Cytochrome b subunit of formate dehydrogenase. (211 aa)
rsxEElectron transport complex RsxE subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. (230 aa)
rsxGElectron transport complex protein RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the RnfG family. (206 aa)
rnfDElectron transport complex protein RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the NqrB/RnfD family. (352 aa)
ESE86985.1Electron transport complex protein RnfC. (78 aa)
msrQSulfite oxidase subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. MsrQ p [...] (199 aa)
ESE86648.1Anaerobic dimethyl sulfoxide reductase subunit A; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
ESE86469.1Thiosulfate reductase PhsA; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (758 aa)
ESE86471.1COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein). (254 aa)
ESE86481.1Polyhedral body protein; COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC. (451 aa)
ESE86204.1Flavodoxin FldB; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (173 aa)
bisCBiotin sulfoxide reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (777 aa)
ESE85808.1Electron transport protein ysaA; COG1142 Fe-S-cluster-containing hydrogenase components 2. (157 aa)
ESE85942.1COG1858 Cytochrome c peroxidase. (466 aa)
ESE85944.1Trimethylamine N-oxide reductase I catalytic subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (850 aa)
ESE85945.1COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; Belongs to the TorC/TorY family. (394 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (576 aa)
ESE85308.1COG3302 DMSO reductase anchor subunit. (257 aa)
ESE85310.1Anaerobic dimethyl sulfoxide reductase chain a; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
norVAnaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (479 aa)
ESE85191.1Formate dehydrogenase-H ferredoxin subunit; COG1142 Fe-S-cluster-containing hydrogenase components 2. (181 aa)
ESE85194.1COG3260 Ni,Fe-hydrogenase III small subunit. (255 aa)
hycECOG3262 Ni,Fe-hydrogenase III component G. (569 aa)
hycDHydrogenase 3 membrane subunit; COG0650 Formate hydrogenlyase subunit 4. (307 aa)
ESE85198.1COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit. (608 aa)
ESE85199.1Formate hydrogenlyase subunit B; COG1142 Fe-S-cluster-containing hydrogenase components 2. (202 aa)
ESE84769.1COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (1174 aa)
azoRAzoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (201 aa)
ESE84781.1COG3038 Cytochrome B561. (176 aa)
ESE84850.1COG2864 Cytochrome b subunit of formate dehydrogenase. (218 aa)
ESE84872.1COG1740 Ni,Fe-hydrogenase I small subunit. (367 aa)
ESE84873.1COG0374 Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (600 aa)
ESE84874.1COG1969 Ni,Fe-hydrogenase I cytochrome b subunit. (247 aa)
ESE84878.1Hydrogenase-1 operon protein HyaF2; COG1773 Rubredoxin. (353 aa)
ESE84879.1Dehydrogenase protein; COG0374 Ni,Fe-hydrogenase I large subunit. (295 aa)
ESE84912.1Anaerobic dimethyl sulfoxide reductase chain a; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (812 aa)
ESE84913.1Anaerobic dimethyl sulfoxide reductase chain a; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (811 aa)
ESE84915.1Anaerobic dimethyl sulfoxide reductase, C subunit; COG3302 DMSO reductase anchor subunit. (287 aa)
ESE84259.1COG2311 Predicted membrane protein. (380 aa)
ESE83211.1Anaerobic reductase component; COG3302 DMSO reductase anchor subunit. (269 aa)
ESE83213.1Dimethyl sulfoxide reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (792 aa)
ESE83221.1Ferredoxin, 2Fe-2S type, ISC system; COG0633 Ferredoxin. (111 aa)
ESE82731.1Hypothetical protein; COG3038 Cytochrome B561. (190 aa)
ESE82823.1COG3038 Cytochrome B561. (176 aa)
grxACOG0695 Glutaredoxin and related proteins. (87 aa)
hemGProtoporphyrinogen oxidase; COG4635 Flavodoxin. (181 aa)
ESE82128.1Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (176 aa)
sdhCCOG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (129 aa)
sdhACOG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhBCOG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
ESE82184.1COG1271 Cytochrome bd-type quinol oxidase, subunit 1. (522 aa)
ESE82185.1COG1294 Cytochrome bd-type quinol oxidase, subunit 2. (379 aa)
ESE82186.1Cyd operon protein YbgT; COG4890 Predicted outer membrane lipoprotein. (37 aa)
ESE81939.1Electron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (625 aa)
rsxBElectron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (192 aa)
rsxAElectron transport complex protein RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. (193 aa)
ESE81979.1COG3302 DMSO reductase anchor subunit. (285 aa)
ESE81783.1COG1740 Ni,Fe-hydrogenase I small subunit. (372 aa)
ESE81784.1Hydrogenase 2 protein HybA; COG0437 Fe-S-cluster-containing hydrogenase components 1. (328 aa)
ESE81786.1COG0374 Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa)
ESE81607.1COG1294 Cytochrome bd-type quinol oxidase, subunit 2. (378 aa)
ESE81608.1COG1271 Cytochrome bd-type quinol oxidase, subunit 1. (514 aa)
ESE81612.1COG1969 Ni,Fe-hydrogenase I cytochrome b subunit. (243 aa)
ESE81613.1COG0374 Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)
ESE81614.1COG1740 Ni,Fe-hydrogenase I small subunit. (372 aa)
dipZThiol:disulfide interchange protein precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (567 aa)
ESE81392.1COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
ESE81393.1COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (596 aa)
ESE81013.1COG0716 Flavodoxins. (149 aa)
Your Current Organism:
Salmonella enterica indica
NCBI taxonomy Id: 1173950
Other names: S. enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121, Salmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.