node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESE81473.1 | ESE83168.1 | SEI61121_20131 | SEI61121_14613 | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Aminoglycoside/multidrug efflux system; COG0841 Cation/multidrug efflux pump. | 0.729 |
ESE81473.1 | ESE86686.1 | SEI61121_20131 | SEI61121_04754 | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug efflux system protein AcrF; COG0841 Cation/multidrug efflux pump. | 0.708 |
ESE81473.1 | ESE87538.1 | SEI61121_20131 | SEI61121_02055 | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Hypothetical protein; COG0841 Cation/multidrug efflux pump. | 0.672 |
ESE81473.1 | ESE87649.1 | SEI61121_20131 | SEI61121_02610 | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug efflux system protein AcrB; COG0841 Cation/multidrug efflux pump. | 0.716 |
ESE83168.1 | ESE81473.1 | SEI61121_14613 | SEI61121_20131 | Aminoglycoside/multidrug efflux system; COG0841 Cation/multidrug efflux pump. | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.729 |
ESE83168.1 | ESE84091.1 | SEI61121_14613 | SEI61121_13138 | Aminoglycoside/multidrug efflux system; COG0841 Cation/multidrug efflux pump. | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | 0.638 |
ESE83168.1 | emrD | SEI61121_14613 | SEI61121_09109 | Aminoglycoside/multidrug efflux system; COG0841 Cation/multidrug efflux pump. | Multidrug resistance protein D; COG0477 Permeases of the major facilitator superfamily. | 0.512 |
ESE83168.1 | mdtK | SEI61121_14613 | SEI61121_04456 | Aminoglycoside/multidrug efflux system; COG0841 Cation/multidrug efflux pump. | Multidrug efflux protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | 0.795 |
ESE83811.1 | mdtK | SEI61121_13474 | SEI61121_04456 | DNA-damage-inducible SOS response protein; COG0534 Na+-driven multidrug efflux pump. | Multidrug efflux protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | 0.513 |
ESE84091.1 | ESE83168.1 | SEI61121_13138 | SEI61121_14613 | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | Aminoglycoside/multidrug efflux system; COG0841 Cation/multidrug efflux pump. | 0.638 |
ESE84091.1 | ESE86686.1 | SEI61121_13138 | SEI61121_04754 | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | Multidrug efflux system protein AcrF; COG0841 Cation/multidrug efflux pump. | 0.633 |
ESE84091.1 | ESE87649.1 | SEI61121_13138 | SEI61121_02610 | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | Multidrug efflux system protein AcrB; COG0841 Cation/multidrug efflux pump. | 0.507 |
ESE84091.1 | emrD | SEI61121_13138 | SEI61121_09109 | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | Multidrug resistance protein D; COG0477 Permeases of the major facilitator superfamily. | 0.606 |
ESE84091.1 | mdtK | SEI61121_13138 | SEI61121_04456 | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | Multidrug efflux protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | 0.512 |
ESE86686.1 | ESE81473.1 | SEI61121_04754 | SEI61121_20131 | Multidrug efflux system protein AcrF; COG0841 Cation/multidrug efflux pump. | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.708 |
ESE86686.1 | ESE84091.1 | SEI61121_04754 | SEI61121_13138 | Multidrug efflux system protein AcrF; COG0841 Cation/multidrug efflux pump. | Multidrug efflux system protein EmrA; COG1566 Multidrug resistance efflux pump. | 0.633 |
ESE86686.1 | acrZ | SEI61121_04754 | SEI61121_16702 | Multidrug efflux system protein AcrF; COG0841 Cation/multidrug efflux pump. | Hypothetical protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. | 0.601 |
ESE86686.1 | mdtK | SEI61121_04754 | SEI61121_04456 | Multidrug efflux system protein AcrF; COG0841 Cation/multidrug efflux pump. | Multidrug efflux protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | 0.459 |
ESE87538.1 | ESE81473.1 | SEI61121_02055 | SEI61121_20131 | Hypothetical protein; COG0841 Cation/multidrug efflux pump. | Macrolide transporter subunit MacA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.672 |
ESE87538.1 | acrZ | SEI61121_02055 | SEI61121_16702 | Hypothetical protein; COG0841 Cation/multidrug efflux pump. | Hypothetical protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. | 0.559 |