STRINGSTRING
ESE87954.1 ESE87954.1 ESE88130.1 ESE88130.1 msrA msrA ESE88241.1 ESE88241.1 ulaG ulaG katG katG ESE87524.1 ESE87524.1 ESE87543.1 ESE87543.1 ESE87568.1 ESE87568.1 ESE87580.1 ESE87580.1 ESE87588.1 ESE87588.1 secD secD secF secF ribD ribD ESE87612.1 ESE87612.1 ampG ampG ESE87634.1 ESE87634.1 ESE87635.1 ESE87635.1 ESE87636.1 ESE87636.1 ESE87678.1 ESE87678.1 ESE87684.1 ESE87684.1 ESE87758.1 ESE87758.1 ESE87341.1 ESE87341.1 ESE87350.1 ESE87350.1 yfcJ yfcJ ESE87293.1 ESE87293.1 ESE86998.1 ESE86998.1 ESE87006.1 ESE87006.1 ESE86955.1 ESE86955.1 ESE86959.1 ESE86959.1 ESE86968.1 ESE86968.1 ESE86888.1 ESE86888.1 ESE86893.1 ESE86893.1 nanT nanT ESE86757.1 ESE86757.1 secG secG ESE86790.1 ESE86790.1 ESE86642.1 ESE86642.1 ESE86643.1 ESE86643.1 ESE86556.1 ESE86556.1 ESE86370.1 ESE86370.1 ESE86371.1 ESE86371.1 ESE86438.1 ESE86438.1 lplT lplT ESE86180.1 ESE86180.1 ESE86262.1 ESE86262.1 ESE85681.1 ESE85681.1 yhhS yhhS ESE85757.1 ESE85757.1 ESE85777.1 ESE85777.1 ESE85778.1 ESE85778.1 ESE85779.1 ESE85779.1 ESE85781.1 ESE85781.1 rpoZ rpoZ nepI nepI emrD emrD mdtL mdtL ESE85969.1 ESE85969.1 ESE85404.1 ESE85404.1 mdtD mdtD ESE85466.1 ESE85466.1 ESE85325.1 ESE85325.1 ESE85372.1 ESE85372.1 ESE85253.1 ESE85253.1 ESE84715.1 ESE84715.1 tpx tpx ESE84752.1 ESE84752.1 ESE84793.1 ESE84793.1 ESE84847.1 ESE84847.1 ESE84866.1 ESE84866.1 ESE84877.1 ESE84877.1 ESE84881.1 ESE84881.1 sotB sotB ESE84894.1 ESE84894.1 msbA msbA ESE84947.1 ESE84947.1 ESE84472.1 ESE84472.1 aceF aceF secA secA ESE84278.1 ESE84278.1 ESE84290.1 ESE84290.1 ESE84292.1 ESE84292.1 ESE84185.1 ESE84185.1 emrB emrB ESE84093.1 ESE84093.1 ESE84131.1 ESE84131.1 ESE84080.1 ESE84080.1 ESE83827.1 ESE83827.1 ESE83452.1 ESE83452.1 secE secE rpoB rpoB rpoC rpoC bcp bcp ndk ndk ESE83083.1 ESE83083.1 mdtG mdtG ESE82811.1 ESE82811.1 ESE82825.1 ESE82825.1 ESE82826.1 ESE82826.1 ESE82827.1 ESE82827.1 ESE82560.1 ESE82560.1 ESE82606.1 ESE82606.1 ESE82607.1 ESE82607.1 ESE82608.1 ESE82608.1 ESE82616.1 ESE82616.1 ESE82660.1 ESE82660.1 trxA trxA ESE82123.1 ESE82123.1 ESE82165.1 ESE82165.1 ESE81956.1 ESE81956.1 ESE81969.1 ESE81969.1 ESE81670.1 ESE81670.1 ESE81542.1 ESE81542.1 ESE81559.1 ESE81559.1 ESE81610.1 ESE81610.1 ESE81487.1 ESE81487.1 rpoA rpoA secY secY ESE81449.1 ESE81449.1 ESE81451.1 ESE81451.1 ESE81237.1 ESE81237.1 ESE81240.1 ESE81240.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ESE87954.1Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. (392 aa)
ESE88130.1Multidrug efflux system protein MdtM; COG0477 Permeases of the major facilitator superfamily. (413 aa)
msrAMethionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (212 aa)
ESE88241.1COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1. (206 aa)
ulaGL-ascorbate 6-phosphate lactonase; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family. (354 aa)
katGCatalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (726 aa)
ESE87524.1COG3203 Outer membrane protein (porin); Belongs to the Gram-negative porin family. (350 aa)
ESE87543.1Putative sialic acid transporter; COG0477 Permeases of the major facilitator superfamily. (417 aa)
ESE87568.1Drug efflux system protein MdtG; COG0477 Permeases of the major facilitator superfamily. (403 aa)
ESE87580.1MFS transport protein AraJ; COG2814 Arabinose efflux permease. (390 aa)
ESE87588.1Peroxidase; COG0450 Peroxiredoxin. (200 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (615 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (323 aa)
ribDDiaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
ESE87612.1Inner membrane transport protein yajR; COG0477 Permeases of the major facilitator superfamily. (455 aa)
ampGMuropeptide transporter; COG0477 Permeases of the major facilitator superfamily. (491 aa)
ESE87634.1Hypothetical protein; COG1522 Transcriptional regulators. (152 aa)
ESE87635.1Multidrug ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. (590 aa)
ESE87636.1Multidrug ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. (593 aa)
ESE87678.1COG3118 Thioredoxin domain-containing protein. (284 aa)
ESE87684.1Porin; COG3203 Outer membrane protein (porin). (377 aa)
ESE87758.1Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
ESE87341.1COG3203 Outer membrane protein (porin); Belongs to the Gram-negative porin family. (378 aa)
ESE87350.1Transmembrane transport protein; COG0477 Permeases of the major facilitator superfamily. (396 aa)
yfcJTransporter; COG0477 Permeases of the major facilitator superfamily. (392 aa)
ESE87293.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (206 aa)
ESE86998.1COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1. (272 aa)
ESE87006.1Elongation factor Tu; COG0050 GTPases - translation elongation factors. (392 aa)
ESE86955.1Transporter; COG0477 Permeases of the major facilitator superfamily. (401 aa)
ESE86959.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (193 aa)
ESE86968.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (173 aa)
ESE86888.1COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (139 aa)
ESE86893.1Alpha-ketoglutarate transporter; COG0477 Permeases of the major facilitator superfamily. (433 aa)
nanTSialic acid transporter; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family. (496 aa)
ESE86757.1Mce family protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component. (183 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (110 aa)
ESE86790.1Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. (335 aa)
ESE86642.1COG0492 Thioredoxin reductase. (322 aa)
ESE86643.1COG1522 Transcriptional regulators. (164 aa)
ESE86556.1COG3203 Outer membrane protein (porin); Belongs to the Gram-negative porin family. (393 aa)
ESE86370.1Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. (403 aa)
ESE86371.1COG2375 Siderophore-interacting protein. (295 aa)
ESE86438.1Sialic acid transporter; COG0477 Permeases of the major facilitator superfamily. (426 aa)
lplTLysophospholipid transporter LplT; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. (398 aa)
ESE86180.1Arabinose-proton symporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (471 aa)
ESE86262.1D-galactose transporter GalP; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (464 aa)
ESE85681.1Periplasmic phosphate-binding protein; COG0226 ABC-type phosphate transport system, periplasmic component. (486 aa)
yhhSCOG0477 Permeases of the major facilitator superfamily. (405 aa)
ESE85757.1Sugar (and other) transporter; COG0477 Permeases of the major facilitator superfamily. (440 aa)
ESE85777.1COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (300 aa)
ESE85778.1Dipeptide transporter permease DppB; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (339 aa)
ESE85779.1Dipeptide ABC transporter periplasmic substrate-binding protein DppA; COG0747 ABC-type dipeptide transport system, periplasmic component. (535 aa)
ESE85781.1Hypothetical protein. (374 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa)
nepIRibonucleoside transporter; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine; Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily. (394 aa)
emrDMultidrug resistance protein D; COG0477 Permeases of the major facilitator superfamily. (394 aa)
mdtLMultidrug efflux system protein MdtL; COG0477 Permeases of the major facilitator superfamily. (395 aa)
ESE85969.1Phosphate ABC transporter periplasmic substrate-binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
ESE85404.1COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (149 aa)
mdtDTransporter; COG0477 Permeases of the major facilitator superfamily. (470 aa)
ESE85466.1Putative n-hydroxybenzoate transporter; COG0477 Permeases of the major facilitator superfamily. (452 aa)
ESE85325.1Proline/glycine betaine transporter; COG0477 Permeases of the major facilitator superfamily. (500 aa)
ESE85372.1Hypothetical protein. (3061 aa)
ESE85253.1Membrane transport protein; COG0477 Permeases of the major facilitator superfamily. (402 aa)
ESE84715.1Antimicrobial peptide ABC transporter periplasmic binding protein SapA; COG4166 ABC-type oligopeptide transport system, periplasmic component. (549 aa)
tpxLipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (168 aa)
ESE84752.1Thiol peroxidase; COG2077 Peroxiredoxin. (185 aa)
ESE84793.1COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
ESE84847.1COG3203 Outer membrane protein (porin); Belongs to the Gram-negative porin family. (359 aa)
ESE84866.1COG0477 Permeases of the major facilitator superfamily. (413 aa)
ESE84877.1Hydrogenase-1 operon protein HyaE2; COG0526 Thiol-disulfide isomerase and thioredoxins. (136 aa)
ESE84881.1COG3203 Outer membrane protein (porin); Belongs to the Gram-negative porin family. (372 aa)
sotBArabinose transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family. (396 aa)
ESE84894.1Transporter; COG0477 Permeases of the major facilitator superfamily. (395 aa)
msbALipid transporter ATP-binding/permease protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)
ESE84947.1COG3203 Outer membrane protein (porin); Belongs to the Gram-negative porin family. (250 aa)
ESE84472.1Inner membrane protein; COG0477 Permeases of the major facilitator superfamily. (433 aa)
aceFPyruvate dehydrogenase dihydrolipoyltransacetylase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa)
ESE84278.1Sugar efflux transporter B; COG0477 Permeases of the major facilitator superfamily. (393 aa)
ESE84290.1Microcin C ABC transporter ATP-binding protein YejF; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily. (529 aa)
ESE84292.1Bicyclomycin/multidrug efflux system; COG0477 Permeases of the major facilitator superfamily. (396 aa)
ESE84185.1Ig domain-containing protein; COG2041 Sulfite oxidase and related enzymes. (475 aa)
emrBMultidrug resistance protein B; COG0477 Permeases of the major facilitator superfamily. (512 aa)
ESE84093.1COG0477 Permeases of the major facilitator superfamily. (394 aa)
ESE84131.1Iron transporter: fur regulated; COG1132 ABC-type multidrug transport system, ATPase and permease components. (1217 aa)
ESE84080.1Ig domain-containing protein. (336 aa)
ESE83827.1D-xylose transporter XylE; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
ESE83452.1Elongation factor Tu; COG0050 GTPases - translation elongation factors. (140 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa)
bcpThioredoxin-dependent thiol peroxidase; COG1225 Peroxiredoxin. (156 aa)
ndkMultifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
ESE83083.1Elongation factor Tu; COG0050 GTPases - translation elongation factors. (191 aa)
mdtGDrug efflux system protein MdtG; COG0477 Permeases of the major facilitator superfamily. (404 aa)
ESE82811.1E3 ubiquitin-protein ligase SlrP; COG4886 Leucine-rich repeat (LRR) protein. (789 aa)
ESE82825.1Nickel ABC transporter periplasmic nickel-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component. (544 aa)
ESE82826.1Inner membrane transport protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (324 aa)
ESE82827.1Nickel/di-oligopepetide ABC transporter permease subunit; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (270 aa)
ESE82560.1E3 ubiquitin-protein ligase SlrP; COG4886 Leucine-rich repeat (LRR) protein. (755 aa)
ESE82606.1Glutathione ABC transporter substrate-binding protein GsiB; COG0747 ABC-type dipeptide transport system, periplasmic component. (512 aa)
ESE82607.1Glutathione ABC transporter permease GsiC; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (306 aa)
ESE82608.1Glutathione ABC transporter permease GsiD; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (303 aa)
ESE82616.1Multidrug efflux system translocase MdfA; COG0477 Permeases of the major facilitator superfamily. (416 aa)
ESE82660.1Putative transposase. (397 aa)
trxAThioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (109 aa)
ESE82123.1Citrate-proton symporter; COG0477 Permeases of the major facilitator superfamily. (434 aa)
ESE82165.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa)
ESE81956.1COG3203 Outer membrane protein (porin). (383 aa)
ESE81969.1Inner membrane transport protein YnfM; COG0477 Permeases of the major facilitator superfamily. (417 aa)
ESE81670.1COG2375 Siderophore-interacting protein. (255 aa)
ESE81542.1Transposase. (140 aa)
ESE81559.1Transport protein; COG0477 Permeases of the major facilitator superfamily. (457 aa)
ESE81610.1Hydrogenase-1 operon protein HyaE; COG0526 Thiol-disulfide isomerase and thioredoxins. (134 aa)
ESE81487.1Putative colicin activity protein. (690 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa)
ESE81449.1Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (158 aa)
ESE81451.1Elongation factor Tu; COG0050 GTPases - translation elongation factors. (123 aa)
ESE81237.1Ferritin-like protein; Iron-storage protein. (167 aa)
ESE81240.1Ferritin; Iron-storage protein. (165 aa)
Your Current Organism:
Salmonella enterica indica
NCBI taxonomy Id: 1173950
Other names: S. enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121, Salmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121
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