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ANH79575.1 ANH79575.1 ANH79603.1 ANH79603.1 ANH79742.1 ANH79742.1 ANH79797.1 ANH79797.1 sucD sucD ANH83646.1 ANH83646.1 ANH79912.1 ANH79912.1 ANH79915.1 ANH79915.1 ANH79917.1 ANH79917.1 ilvD ilvD ANH79923.1 ANH79923.1 ANH79925.1 ANH79925.1 ANH79978.1 ANH79978.1 ANH79979.1 ANH79979.1 ANH80101.1 ANH80101.1 proC proC sucC sucC ANH80312.1 ANH80312.1 ANH80371.1 ANH80371.1 ANH80470.1 ANH80470.1 ANH80472.1 ANH80472.1 gcvP gcvP A8C56_05575 A8C56_05575 ANH83734.1 ANH83734.1 purU purU ANH80841.1 ANH80841.1 ANH80969.1 ANH80969.1 ANH81222.1 ANH81222.1 ANH81270.1 ANH81270.1 pdhA pdhA ANH81379.1 ANH81379.1 ANH81392.1 ANH81392.1 ANH81499.1 ANH81499.1 ANH81518.1 ANH81518.1 ANH81539.1 ANH81539.1 ANH81549.1 ANH81549.1 ANH81575.1 ANH81575.1 mdh mdh pckA pckA ANH81870.1 ANH81870.1 ANH81911.1 ANH81911.1 ANH81938.1 ANH81938.1 leuC leuC ANH81974.1 ANH81974.1 ANH81975.1 ANH81975.1 leuB leuB mqo mqo ANH82145.1 ANH82145.1 ANH82154.1 ANH82154.1 ANH82166.1 ANH82166.1 ANH82246.1 ANH82246.1 glyA glyA ANH82409.1 ANH82409.1 sdhA sdhA ANH82412.1 ANH82412.1 ANH82565.1 ANH82565.1 gltD gltD ANH82747.1 ANH82747.1 ANH82748.1 ANH82748.1 prpB prpB gcvH gcvH fumC fumC gcvT gcvT ANH83466.1 ANH83466.1 ANH83537.1 ANH83537.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANH79575.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
ANH79603.1Amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ANH79742.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (859 aa)
ANH79797.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
ANH83646.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (924 aa)
ANH79912.1Ketol-acid reductoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ANH79915.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
ANH79917.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (561 aa)
ANH79923.13-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
ANH79925.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the alpha-IPM synthase/homocitrate synthase family. (386 aa)
ANH79978.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (923 aa)
ANH79979.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (755 aa)
ANH80101.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (729 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (403 aa)
ANH80312.1Alpha-hydroxy-acid oxidizing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
ANH80371.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (544 aa)
ANH80470.12-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (918 aa)
ANH80472.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (421 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (972 aa)
A8C56_05575Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
ANH83734.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (552 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (277 aa)
ANH80841.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (797 aa)
ANH80969.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (410 aa)
ANH81222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
ANH81270.1Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa)
ANH81379.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (329 aa)
ANH81392.1Ornithine--oxo-acid transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (410 aa)
ANH81499.1Citrate (Si)-synthase, eukaryotic; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (441 aa)
ANH81518.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
ANH81539.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (472 aa)
ANH81549.1Diapophytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
ANH81575.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
ANH81870.1Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (579 aa)
ANH81911.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (570 aa)
ANH81938.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (452 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
ANH81974.13-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa)
ANH81975.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (505 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (356 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
ANH82145.1Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
ANH82154.11-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (543 aa)
ANH82166.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (795 aa)
ANH82246.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (446 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
ANH82409.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
ANH82412.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
ANH82565.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1504 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
ANH82747.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
ANH82748.12-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (384 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (301 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
ANH83466.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (661 aa)
ANH83537.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
Your Current Organism:
Niabella ginsenosidivorans
NCBI taxonomy Id: 1176587
Other names: JCM 18199, KACC 16620, N. ginsenosidivorans, Niabella sp. BS26, strain BS26
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