STRINGSTRING
EKF75856.1 EKF75856.1 EKF75882.1 EKF75882.1 EKF75885.1 EKF75885.1 EKF75894.1 EKF75894.1 thiL thiL EKF75970.1 EKF75970.1 ppk ppk EKF76037.1 EKF76037.1 EKF76047.1 EKF76047.1 EKF76061.1 EKF76061.1 aroK aroK EKF76125.1 EKF76125.1 EKF76137.1 EKF76137.1 EKF76141.1 EKF76141.1 EKF75548.1 EKF75548.1 EKF75549.1 EKF75549.1 EKF75555.1 EKF75555.1 EKF75669.1 EKF75669.1 ndk ndk EKF75769.1 EKF75769.1 nadD nadD EKF75820.1 EKF75820.1 EKF75821.1 EKF75821.1 pfp pfp anmK anmK EKF75327.1 EKF75327.1 EKF75333.1 EKF75333.1 srkA srkA EKF75342.1 EKF75342.1 pcnB pcnB EKF75345.1 EKF75345.1 EKF75346.1 EKF75346.1 pnp pnp EKF75420.1 EKF75420.1 hldE hldE EKF75431.1 EKF75431.1 EKF75435.1 EKF75435.1 glnE glnE EKF75461.1 EKF75461.1 EKF75484.1 EKF75484.1 cobS cobS EKF75514.1 EKF75514.1 EKF75517.1 EKF75517.1 EKF75189.1 EKF75189.1 EKF75199.1 EKF75199.1 tmk tmk kdsB kdsB lpxK lpxK nadK nadK EKF75300.1 EKF75300.1 EKF75305.1 EKF75305.1 EKF75038.1 EKF75038.1 EKF75039.1 EKF75039.1 EKF75053.1 EKF75053.1 EKF75082.1 EKF75082.1 EKF75085.1 EKF75085.1 glnD glnD pyrH pyrH EKF75109.1 EKF75109.1 dnaE dnaE ispD ispD EKF75130.1 EKF75130.1 EKF75148.1 EKF75148.1 EKF75151.1 EKF75151.1 EKF74810.1 EKF74810.1 EKF74831.1 EKF74831.1 EKF74832.1 EKF74832.1 EKF74839.1 EKF74839.1 dnaQ dnaQ EKF74905.1 EKF74905.1 EKF74735.1 EKF74735.1 EKF74743.1 EKF74743.1 EKF74782.1 EKF74782.1 EKF74793.1 EKF74793.1 EKF74607.1 EKF74607.1 EKF74613.1 EKF74613.1 dnaG dnaG EKF74628.1 EKF74628.1 cca cca EKF74636.1 EKF74636.1 EKF74644.1 EKF74644.1 EKF74656.1 EKF74656.1 EKF74659.1 EKF74659.1 EKF74519.1 EKF74519.1 EKF74529.1 EKF74529.1 slyX slyX EKF74568.1 EKF74568.1 EKF74572.1 EKF74572.1 EKF74410.1 EKF74410.1 rpoA rpoA EKF74463.1 EKF74463.1 EKF74465.1 EKF74465.1 proB proB EKF74484.1 EKF74484.1 EKF74498.1 EKF74498.1 EKF74511.1 EKF74511.1 tsaC tsaC glpK glpK rpoZ rpoZ gmk gmk EKF74332.1 EKF74332.1 rph rph argB argB EKF74391.1 EKF74391.1 EKF74232.1 EKF74232.1 EKF74236.1 EKF74236.1 coaE coaE mraY mraY EKF74113.1 EKF74113.1 EKF74114.1 EKF74114.1 EKF74120.1 EKF74120.1 prs prs ispE ispE EKF74175.1 EKF74175.1 EKF74177.1 EKF74177.1 EKF74191.1 EKF74191.1 sat sat EKF74062.1 EKF74062.1 EKF74078.1 EKF74078.1 EKF74099.1 EKF74099.1 EKF74100.1 EKF74100.1 EKF73977.1 EKF73977.1 adk adk EKF73932.1 EKF73932.1 EKF73819.1 EKF73819.1 EKF73766.1 EKF73766.1 EKF72771.1 EKF72771.1 dnaX dnaX coaX coaX EKF72805.1 EKF72805.1 rpoC rpoC rpoB rpoB EKF72875.1 EKF72875.1 pgk pgk dinB dinB EKF72944.1 EKF72944.1 EKF72954.1 EKF72954.1 polA polA EKF73034.1 EKF73034.1 EKF73063.1 EKF73063.1 EKF73058.1 EKF73058.1 EKF73053.1 EKF73053.1 EKF73070.1 EKF73070.1 coaD coaD EKF73228.1 EKF73228.1 EKF73203.1 EKF73203.1 glmU glmU EKF73300.1 EKF73300.1 cysC cysC EKF73283.1 EKF73283.1 EKF73308.1 EKF73308.1 thrB thrB EKF73420.1 EKF73420.1 EKF73411.1 EKF73411.1 cmk cmk EKF73470.1 EKF73470.1 EKF73448.1 EKF73448.1 EKF73526.1 EKF73526.1 selO selO EKF73511.1 EKF73511.1 EKF73576.1 EKF73576.1 EKF73569.1 EKF73569.1 EKF73601.1 EKF73601.1 EKF73600.1 EKF73600.1 EKF73596.1 EKF73596.1 EKF73583.1 EKF73583.1 EKF73678.1 EKF73678.1 EKF73670.1 EKF73670.1 EKF73745.1 EKF73745.1 EKF73742.1 EKF73742.1 EKF73707.1 EKF73707.1 EKF73808.1 EKF73808.1 EKF73782.1 EKF73782.1 EKF73769.1 EKF73769.1 EKF73767.1 EKF73767.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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EKF75856.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (407 aa)
EKF75882.1Na-solute symporter/sensory box histidinekinase; COG0591 Na+/proline symporter. (1158 aa)
EKF75885.1Hypothetical protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains. (603 aa)
EKF75894.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (421 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (308 aa)
EKF75970.1RelA/SpoT domain-containing protein; COG2357 Uncharacterized protein conserved in bacteria. (356 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (696 aa)
EKF76037.1COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (433 aa)
EKF76047.1Hypothetical protein; COG1396 Predicted transcriptional regulators. (137 aa)
EKF76061.1Signal peptide protein. (119 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (164 aa)
EKF76125.1Ubiquinone biosynthesis protein; COG0661 Predicted unusual protein kinase. (534 aa)
EKF76137.1Sensory box histidine kinase NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. (369 aa)
EKF76141.1COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain. (361 aa)
EKF75548.1Hypothetical protein; COG2203 FOG: GAF domain. (255 aa)
EKF75549.1ColS; COG0642 Signal transduction histidine kinase. (421 aa)
EKF75555.1Hypothetical protein; COG2199 FOG: GGDEF domain. (263 aa)
EKF75669.1Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. (643 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
EKF75769.1COG1466 DNA polymerase III, delta subunit. (333 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (228 aa)
EKF75820.1Twin-arginine translocation pathway signal; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (411 aa)
EKF75821.1Two-component sensor histidine kinase protein; COG0642 Signal transduction histidine kinase. (1113 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (363 aa)
EKF75327.1Adenine phosphoribosyltransferase; COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (253 aa)
EKF75333.1COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (334 aa)
srkASerine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (318 aa)
EKF75342.1Sensory box histidine kinase; COG0591 Na+/proline symporter. (984 aa)
pcnBpoly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (440 aa)
EKF75345.1COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (173 aa)
EKF75346.1COG1428 Deoxynucleoside kinases. (230 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (697 aa)
EKF75420.1COG0642 Signal transduction histidine kinase. (629 aa)
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (476 aa)
EKF75431.1COG3642 Mn2+-dependent serine/threonine protein kinase. (238 aa)
EKF75435.1COG0515 Serine/threonine protein kinase. (262 aa)
glnEGlutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (954 aa)
EKF75461.1Two-component system sensor protein, alginate biosynthesis; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (345 aa)
EKF75484.1Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. (756 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (243 aa)
EKF75514.1Hypothetical protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (175 aa)
EKF75517.1Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (170 aa)
EKF75189.1COG0631 Serine/threonine protein phosphatase. (562 aa)
EKF75199.1DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. (335 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (252 aa)
lpxKTetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (331 aa)
nadKNicotinamide adenine dinucleotide kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (310 aa)
EKF75300.1Hypothetical protein. (200 aa)
EKF75305.1Phosphotransferase-histidine kinase family protein; COG0642 Signal transduction histidine kinase. (834 aa)
EKF75038.1Two-component sensor; COG0642 Signal transduction histidine kinase. (694 aa)
EKF75039.1Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. (930 aa)
EKF75053.1COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. (417 aa)
EKF75082.1Hypothetical protein. (272 aa)
EKF75085.1Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (182 aa)
glnDPII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (887 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (245 aa)
EKF75109.1Phosphatidate cytidylyltransferase; COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. (274 aa)
dnaECOG0587 DNA polymerase III, alpha subunit. (1167 aa)
ispD4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (213 aa)
EKF75130.1COG2035 Predicted membrane protein. (304 aa)
EKF75148.1COG3001 Fructosamine-3-kinase. (288 aa)
EKF75151.1Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (397 aa)
EKF74810.1Hypothetical protein. (231 aa)
EKF74831.1COG0515 Serine/threonine protein kinase. (404 aa)
EKF74832.1Sensory box protein/response regulator; COG0784 FOG: CheY-like receiver. (167 aa)
EKF74839.1COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (361 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (245 aa)
EKF74905.1Hypothetical protein. (561 aa)
EKF74735.1Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase. (439 aa)
EKF74743.1COG4585 Signal transduction histidine kinase. (709 aa)
EKF74782.1COG3530 Uncharacterized protein conserved in bacteria. (71 aa)
EKF74793.1Phospholipase D/transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (520 aa)
EKF74607.1Hypothetical protein; Belongs to the UPF0434 family. (60 aa)
EKF74613.1Siderophore biosynthesis protein; COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily. (231 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (627 aa)
EKF74628.1COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (169 aa)
ccatRNA cytidylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (412 aa)
EKF74636.1PrkA family serine protein kinase; COG2766 Putative Ser protein kinase. (640 aa)
EKF74644.1Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (221 aa)
EKF74656.1COG0642 Signal transduction histidine kinase. (449 aa)
EKF74659.1Hypothetical protein. (113 aa)
EKF74519.1Phospholipase D/transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (464 aa)
EKF74529.1Sensory box protein; COG2202 FOG: PAS/PAC domain. (931 aa)
slyXCOG2900 Uncharacterized protein conserved in bacteria; Belongs to the SlyX family. (68 aa)
EKF74568.1GAF/PAS/GGDEF domain-containing protein; COG2203 FOG: GAF domain. (481 aa)
EKF74572.1ATPase family protein; COG4585 Signal transduction histidine kinase. (698 aa)
EKF74410.1Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (477 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (335 aa)
EKF74463.1COG0642 Signal transduction histidine kinase. (796 aa)
EKF74465.1COG0661 Predicted unusual protein kinase. (442 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa)
EKF74484.1COG0196 FAD synthase; Belongs to the ribF family. (317 aa)
EKF74498.1COG0642 Signal transduction histidine kinase. (517 aa)
EKF74511.1CDP-diacylglycerol--serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (260 aa)
tsaCSua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (182 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (492 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (87 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
EKF74332.1Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (287 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
EKF74391.1COG0642 Signal transduction histidine kinase. (482 aa)
EKF74232.1COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (311 aa)
EKF74236.1Phosphotransferase; COG0642 Signal transduction histidine kinase. (452 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
EKF74113.1Lipid kinase; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. (307 aa)
EKF74114.1COG3205 Predicted membrane protein. (68 aa)
EKF74120.1COG2927 DNA polymerase III, chi subunit. (139 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa)
EKF74175.1Phosphotransferase system, nitrogen regulatory IIA protein; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (157 aa)
EKF74177.1RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (469 aa)
EKF74191.1Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (290 aa)
satCOG2046 ATP sulfurylase (sulfate adenylyltransferase); Belongs to the sulfate adenylyltransferase family. (405 aa)
EKF74062.1Sua5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family. (207 aa)
EKF74078.1COG1070 Sugar (pentulose and hexulose) kinases. (519 aa)
EKF74099.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa)
EKF74100.1PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (272 aa)
EKF73977.1Hypothetical protein; COG0642 Signal transduction histidine kinase. (389 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa)
EKF73932.1Sensor/response regulator hybrid; COG0642 Signal transduction histidine kinase. (904 aa)
EKF73819.1COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (482 aa)
EKF73766.1Diguanylate cyclase; COG2199 FOG: GGDEF domain; overlaps another CDS with the same product name. (367 aa)
EKF72771.1RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (991 aa)
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (379 aa)
coaXTranscriptional activator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (241 aa)
EKF72805.1ABC1/ AarF family protein; COG0661 Predicted unusual protein kinase. (477 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1400 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1380 aa)
EKF72875.1COG0642 Signal transduction histidine kinase. (445 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (368 aa)
EKF72944.1Two-component hybrid chemotactic sensor and regulator; COG0643 Chemotaxis protein histidine kinase and related kinases. (2337 aa)
EKF72954.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (347 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (920 aa)
EKF73034.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (408 aa)
EKF73063.1ABC1 family protein, ubiquinone biosynthesis protein; COG0661 Predicted unusual protein kinase. (553 aa)
EKF73058.1Protein kinase; COG0661 Predicted unusual protein kinase. (404 aa)
EKF73053.1COG1881 Phospholipid-binding protein. (208 aa)
EKF73070.1COG0642 Signal transduction histidine kinase. (739 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
EKF73228.1Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (296 aa)
EKF73203.1Heavy metal sensor histidine kinase; Member of a two-component regulatory system. (468 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (438 aa)
EKF73300.1Tyrosine-protein kinase; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (723 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (203 aa)
EKF73283.1UTP-glucose-1-phosphate uridylyltransferase; COG1210 UDP-glucose pyrophosphorylase. (293 aa)
EKF73308.1Hypothetical protein; COG3344 Retron-type reverse transcriptase. (312 aa)
thrBPhosphotransferase family protein; COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. (311 aa)
EKF73420.1Hypothetical protein; COG2199 FOG: GGDEF domain. (365 aa)
EKF73411.1Phosphate regulon sensor protein PhoR; COG0642 Signal transduction histidine kinase. (436 aa)
cmkCOG0283 Cytidylate kinase. (225 aa)
EKF73470.1ABC1 family protein; COG0661 Predicted unusual protein kinase. (453 aa)
EKF73448.1COG2812 DNA polymerase III, gamma/tau subunits. (164 aa)
EKF73526.1DNA polymerase III subunit epsilon; COG0322 Nuclease subunit of the excinuclease complex. (281 aa)
selOHypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (486 aa)
EKF73511.1Sensor histidine kinase; COG2199 FOG: GGDEF domain. (396 aa)
EKF73576.1Two-component hybrid sensor and regulator; COG2198 FOG: HPt domain. (112 aa)
EKF73569.1Cardiolipin synthase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (483 aa)
EKF73601.1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (194 aa)
EKF73600.1Sensor histidine kinase/respose regulator; COG0642 Signal transduction histidine kinase. (1222 aa)
EKF73596.1Sensory box protein/response regulator; COG0784 FOG: CheY-like receiver. (377 aa)
EKF73583.1Hypothetical protein; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (670 aa)
EKF73678.1Hypothetical protein; COG5519 Superfamily II helicase and inactivated derivatives. (558 aa)
EKF73670.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
EKF73745.1Protein PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains. (147 aa)
EKF73742.1COG0642 Signal transduction histidine kinase. (469 aa)
EKF73707.1Sensory box histidine kinase PhoR; COG4252 Predicted transmembrane sensor domain. (864 aa)
EKF73808.1Hypothetical protein. (314 aa)
EKF73782.1COG0661 Predicted unusual protein kinase. (530 aa)
EKF73769.1COG0642 Signal transduction histidine kinase. (540 aa)
EKF73767.1Diguanylate cyclase; COG2199 FOG: GGDEF domain; overlaps another CDS with the same product name. (367 aa)
Your Current Organism:
Alcanivorax hongdengensis
NCBI taxonomy Id: 1177179
Other names: A. hongdengensis A-11-3, Alcanivorax hongdengensis A-11-3, Alcanivorax hongdengensis str. A-11-3, Alcanivorax hongdengensis strain A-11-3
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