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BN6_00030 BN6_00030 BN6_02560 BN6_02560 prs prs eno eno glpX glpX rpiB rpiB BN6_16120 BN6_16120 pfp pfp eda eda edd edd BN6_19110 BN6_19110 rpe1 rpe1 BN6_52660 BN6_52660 BN6_56730 BN6_56730 BN6_56740 BN6_56740 gntK gntK tkt tkt tal tal pgiA pgiA zwf zwf BN6_62640 BN6_62640 pgl pgl tpiA tpiA pgk pgk gap gap rpe3 rpe3 BN6_66220 BN6_66220 BN6_68150 BN6_68150 pyk pyk BN6_68550 BN6_68550 fas2 fas2 gpmA gpmA fba fba BN6_83140 BN6_83140 rbsK rbsK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BN6_000306-phosphogluconate dehydrogenase-like protein. (304 aa)
BN6_02560Carbohydrate kinase FGGY; Belongs to the FGGY kinase family. (475 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
glpXFructose-1,6-bisphosphatase class 2. (351 aa)
rpiBRibose-5-phosphate isomerase B. (161 aa)
BN6_16120Glycerate kinase; Belongs to the glycerate kinase type-1 family. (340 aa)
pfpPyrophosphate-fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (352 aa)
edaKHG/KDPG aldolase. (206 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (621 aa)
BN6_19110Hypothetical protein. (366 aa)
rpe1Ribulose-phosphate 3-epimerase. (217 aa)
BN6_526606-phosphogluconolactonase. (238 aa)
BN6_56730Transketolase. (310 aa)
BN6_56740Transketolase. (276 aa)
gntKGluconate kinase. (190 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (370 aa)
pgiAGlucose-6-phosphate isomerase; Belongs to the GPI family. (538 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (513 aa)
BN6_62640OpcA family protein. (392 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (240 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (262 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (390 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
rpe3Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa)
BN6_66220PfkB domain protein. (364 aa)
BN6_681506-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
BN6_68550Hypothetical protein; The FAS-operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall). (312 aa)
fas2Ferredoxin. (269 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
BN6_83140Hypothetical protein. (233 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (302 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
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