STRINGSTRING
BN6_09090 BN6_09090 BN6_08690 BN6_08690 BN6_08300 BN6_08300 fumC fumC eno eno menC1 menC1 BN6_03800 BN6_03800 murQ murQ nth nth pheA pheA gmd gmd geoA geoA leuC leuC leuD leuD BN6_71740 BN6_71740 mutM3 mutM3 BN6_70740 BN6_70740 BN6_69920 BN6_69920 dapA5 dapA5 BN6_69370 BN6_69370 hisB hisB trpB3 trpB3 trpA trpA BN6_68230 BN6_68230 BN6_68130 BN6_68130 dapA3 dapA3 griH2 griH2 aroC aroC aroQ aroQ sam27 sam27 BN6_57970 BN6_57970 rfbB1 rfbB1 BN6_55020 BN6_55020 ptlA ptlA BN6_54320 BN6_54320 BN6_46710 BN6_46710 vgb vgb BN6_41260 BN6_41260 mycA mycA dapA1 dapA1 BN6_33090 BN6_33090 BN6_32290 BN6_32290 BN6_32280 BN6_32280 BN6_31000 BN6_31000 acnA acnA BN6_25690 BN6_25690 BN6_24070 BN6_24070 trpB2 trpB2 BN6_22040 BN6_22040 griH1 griH1 BN6_21270 BN6_21270 BN6_20850 BN6_20850 BN6_19350 BN6_19350 psuG psuG fumB fumB edd edd BN6_15150 BN6_15150 BN6_14410 BN6_14410 BN6_13500 BN6_13500 ilvD ilvD BN6_80820 BN6_80820 hemB hemB echA14 echA14 BN6_79750 BN6_79750 nnrE nnrE BN6_77840 BN6_77840 BN6_77820 BN6_77820 rfbB3 rfbB3 hutU hutU thrC thrC BN6_73370 BN6_73370
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BN6_09090MaoC protein. (168 aa)
BN6_08690Enoyl-CoA hydratase/isomerase. (259 aa)
BN6_08300Hypothetical protein. (97 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
menC1Putative o-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (318 aa)
BN6_03800Carbonic anhydrase. (168 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (310 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (255 aa)
pheAPrephenate dehydratase. (311 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (329 aa)
geoAGeosmin synthase. (738 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (470 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
BN6_71740Transferase family protein. (173 aa)
mutM3Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa)
BN6_70740Hypothetical protein. (162 aa)
BN6_69920Hypothetical protein. (135 aa)
dapA5Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa)
BN6_69370Putative DNA glycosylase. (264 aa)
hisBImidazoleglycerol-phosphate dehydratase. (199 aa)
trpB3Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa)
BN6_68230Hypothetical protein. (113 aa)
BN6_68130Carbonate dehydratase. (734 aa)
dapA3Dihydrodipicolinate synthase; Belongs to the DapA family. (283 aa)
griH23-amino-4-hydroxybenzoic acid synthase. (357 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
aroQ3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa)
sam27L-threonine synthase. (430 aa)
BN6_57970Hypothetical protein. (379 aa)
rfbB1dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (335 aa)
BN6_55020Hypothetical protein. (301 aa)
ptlAPentalenene synthase; Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to yield the bicyclic sesquiterpene (2S,10R)-(-)-(E)-beta- caryophyllene via a probable 1,10-cyclization, which could involves the abstraction of the pyrophosphate from FPP to yield a (E,E)- germacradienyl cation. (353 aa)
BN6_54320Putative hydrolase. (359 aa)
BN6_46710Hypothetical protein. (171 aa)
vgbVirginiamycin B lyase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. (288 aa)
BN6_41260Hypothetical protein; 6-pyruvoyl-tetrahydropterin synthase. (144 aa)
mycAMyosin-crossreactive antigen family protein. (589 aa)
dapA1Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (310 aa)
BN6_33090Putative hydrolase. (356 aa)
BN6_32290Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ. (154 aa)
BN6_32280Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ. (112 aa)
BN6_31000Hypothetical protein. (222 aa)
acnAAconitate hydratase. (946 aa)
BN6_25690Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (251 aa)
BN6_24070Hypothetical protein. (156 aa)
trpB2Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (455 aa)
BN6_22040Hypothetical protein. (398 aa)
griH13-amino-4-hydroxybenzoic acid synthase. (397 aa)
BN6_21270Hypothetical protein. (236 aa)
BN6_20850Hypothetical protein. (118 aa)
BN6_19350Acyl dehydratase. (150 aa)
psuGPseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (301 aa)
fumBFumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (555 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (621 aa)
BN6_15150Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (194 aa)
BN6_14410Putative threonine synthase. (420 aa)
BN6_13500Putative DNA glycosylase; Belongs to the FPG family. (267 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (614 aa)
BN6_80820Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (515 aa)
hemBDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (325 aa)
echA14Putative enoyl-CoA hydratase. (253 aa)
BN6_79750Hypothetical protein; Belongs to the UPF0336 family. (149 aa)
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (466 aa)
BN6_77840HhH-GPD family protein. (168 aa)
BN6_77820HhH-GPD base excision DNA repair family protein. (189 aa)
rfbB3dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (339 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (547 aa)
thrCThreonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (358 aa)
BN6_733702-ketocyclohexanecarboxyl-CoA hydrolase. (271 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
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