(15 nodes) Ligase activity, forming phosphoric ester bonds network (Saccharothrix espanaensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	lig-2	Putative DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (515 aa)
	rtcB	RNA-splicing ligase. (384 aa)
	BN6_18810	DNA polymerase LigD, polymerase domain protein. (333 aa)
	ligC	ATP-dependent DNA ligase. (357 aa)
	BN6_24570	DNA polymerase LigD, polymerase domain-containing protein. (258 aa)
	BN6_24580	DNA polymerase LigD, ligase domain-containing protein. (388 aa)
	lig	ATP-dependent DNA ligase. (708 aa)
	BN6_37120	WGR domain-containing protein. (1252 aa)
	BN6_42910	Putative DNA ligase. (492 aa)
	BN6_42920	Putative DNA polymerase, LigD family. (342 aa)
	BN6_43600	Hypothetical protein. (362 aa)
	ligA1	DNA ligase 1; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (663 aa)
	BN6_58390	DNA polymerase LigD, polymerase domain-containing protein. (318 aa)
	BN6_59390	Hypothetical protein. (474 aa)
	BN6_69720	Hypothetical protein. (89 aa)

Your Current Organism:

Saccharothrix espanaensis

NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN6_18810	BN6_24580	BN6_18810	BN6_24580	DNA polymerase LigD, polymerase domain protein.	DNA polymerase LigD, ligase domain-containing protein.	0.901
BN6_18810	BN6_42910	BN6_18810	BN6_42910	DNA polymerase LigD, polymerase domain protein.	Putative DNA ligase.	0.977
BN6_18810	lig-2	BN6_18810	BN6_08010	DNA polymerase LigD, polymerase domain protein.	Putative DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.747
BN6_18810	ligC	BN6_18810	BN6_18930	DNA polymerase LigD, polymerase domain protein.	ATP-dependent DNA ligase.	0.878
BN6_24570	BN6_24580	BN6_24570	BN6_24580	DNA polymerase LigD, polymerase domain-containing protein.	DNA polymerase LigD, ligase domain-containing protein.	0.942
BN6_24570	BN6_42910	BN6_24570	BN6_42910	DNA polymerase LigD, polymerase domain-containing protein.	Putative DNA ligase.	0.977
BN6_24570	lig-2	BN6_24570	BN6_08010	DNA polymerase LigD, polymerase domain-containing protein.	Putative DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.731
BN6_24570	ligC	BN6_24570	BN6_18930	DNA polymerase LigD, polymerase domain-containing protein.	ATP-dependent DNA ligase.	0.872
BN6_24580	BN6_18810	BN6_24580	BN6_18810	DNA polymerase LigD, ligase domain-containing protein.	DNA polymerase LigD, polymerase domain protein.	0.901
BN6_24580	BN6_24570	BN6_24580	BN6_24570	DNA polymerase LigD, ligase domain-containing protein.	DNA polymerase LigD, polymerase domain-containing protein.	0.942
BN6_24580	BN6_42920	BN6_24580	BN6_42920	DNA polymerase LigD, ligase domain-containing protein.	Putative DNA polymerase, LigD family.	0.919
BN6_24580	BN6_43600	BN6_24580	BN6_43600	DNA polymerase LigD, ligase domain-containing protein.	Hypothetical protein.	0.860
BN6_24580	BN6_58390	BN6_24580	BN6_58390	DNA polymerase LigD, ligase domain-containing protein.	DNA polymerase LigD, polymerase domain-containing protein.	0.847
BN6_24580	lig	BN6_24580	BN6_34290	DNA polymerase LigD, ligase domain-containing protein.	ATP-dependent DNA ligase.	0.411
BN6_24580	lig-2	BN6_24580	BN6_08010	DNA polymerase LigD, ligase domain-containing protein.	Putative DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.562
BN6_24580	ligA1	BN6_24580	BN6_44800	DNA polymerase LigD, ligase domain-containing protein.	DNA ligase 1; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	0.543
BN6_42910	BN6_18810	BN6_42910	BN6_18810	Putative DNA ligase.	DNA polymerase LigD, polymerase domain protein.	0.977
BN6_42910	BN6_24570	BN6_42910	BN6_24570	Putative DNA ligase.	DNA polymerase LigD, polymerase domain-containing protein.	0.977
BN6_42910	BN6_42920	BN6_42910	BN6_42920	Putative DNA ligase.	Putative DNA polymerase, LigD family.	0.997
BN6_42910	BN6_43600	BN6_42910	BN6_43600	Putative DNA ligase.	Hypothetical protein.	0.977

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