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poxB poxB dxs3 dxs3 ilvB1 ilvB1 ilvB3 ilvB3 BN6_80170 BN6_80170 kgd kgd menD menD dxs1 dxs1 BN6_37290 BN6_37290 BN6_46450 BN6_46450 mdlC mdlC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
poxBPyruvate dehydrogenase; Belongs to the TPP enzyme family. (596 aa)
dxs31-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (578 aa)
ilvB1Acetolactate synthase I/II/III large subunit; Belongs to the TPP enzyme family. (551 aa)
ilvB3Acetolactate synthase. (612 aa)
BN6_80170Thiamine pyrophosphate protein domain protein,TPP-binding protein. (350 aa)
kgd2-oxoglutarate decarboxylase. (1216 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (563 aa)
dxs11-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (633 aa)
BN6_37290Benzoylformate decarboxylase; Belongs to the TPP enzyme family. (522 aa)
BN6_46450Thiamine pyrophosphate-requiring protein-like protein; Belongs to the TPP enzyme family. (538 aa)
mdlCBenzoylformate decarboxylase; Belongs to the TPP enzyme family. (538 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
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