STRINGSTRING
pheA pheA lysC lysC serB serB relA relA glnD glnD serA serA ilvH ilvH BN6_72240 BN6_72240 hom hom purU purU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pheAPrephenate dehydratase. (311 aa)
lysCAspartate kinase; Belongs to the aspartokinase family. (421 aa)
serBPhosphoserine phosphatase. (408 aa)
relAPutative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (766 aa)
glnD[Protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (800 aa)
serAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
ilvHAcetolactate synthase small subunit. (168 aa)
BN6_72240Amino acid-binding ACT domain protein. (247 aa)
homHomoserine dehydrogenase. (432 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (291 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.