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acsA acsA fadD12 fadD12 BN6_21280 BN6_21280 BN6_21300 BN6_21300 BN6_21380 BN6_21380 nrps1-a3 nrps1-a3 nrps1 nrps1 BN6_22800 BN6_22800 BN6_24010 BN6_24010 nrps2-2 nrps2-2 entE entE BN6_31010 BN6_31010 nrps3-3 nrps3-3 nrps3-2 nrps3-2 nrps3-1 nrps3-1 BN6_32730 BN6_32730 nrps5-a5 nrps5-a5 nrps5-4 nrps5-4 nrps5-3 nrps5-3 nrps5-2 nrps5-2 nrps5-1 nrps5-1 BN6_35920 BN6_35920 BN6_37600 BN6_37600 BN6_38310 BN6_38310 nrps6 nrps6 lcfB lcfB BN6_40590 BN6_40590 nrps7 nrps7 nrps8 nrps8 nrpks8 nrpks8 BN6_46240 BN6_46240 nrps10-1 nrps10-1 nrps10-a6 nrps10-a6 nrps10-4 nrps10-4 nrps10-3 nrps10-3 nrps10-2 nrps10-2 BN6_48510 BN6_48510 BN6_48520 BN6_48520 BN6_50250 BN6_50250 BN6_50260 BN6_50260 nrps12-1 nrps12-1 BN6_53050 BN6_53050 nrps13 nrps13 nrps14-1 nrps14-1 nrps14-2 nrps14-2 nrps14-3 nrps14-3 nrps14-5 nrps14-5 BN6_63880 BN6_63880 BN6_64350 BN6_64350 BN6_78740 BN6_78740 menE menE BN6_80900 BN6_80900 BN6_81150 BN6_81150
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
fadD12Acyl-CoA synthase. (515 aa)
BN6_21280Putative fatty acid CoA ligase. (526 aa)
BN6_21300Putative long-chain-fatty-acid-CoA ligase. (508 aa)
BN6_21380AMP-binding enzyme. (476 aa)
nrps1-a3Amino acid adenylation domain-containing protein. (508 aa)
nrps1Non-ribosomal peptide synthetase. (1022 aa)
BN6_22800Hypothetical protein. (492 aa)
BN6_24010Amino acid adenyltransferase; Belongs to the ATP-dependent AMP-binding enzyme family. (506 aa)
nrps2-2Non-ribosomal peptide synthetase. (6716 aa)
entE2,3-dihydroxybenzoate-AMP ligase. (535 aa)
BN6_31010AMP-dependent synthetase and ligase. (509 aa)
nrps3-3Non-ribosomal peptide synthetase. (4893 aa)
nrps3-2Non-ribosomal peptide synthetase. (6194 aa)
nrps3-1Non-ribosomal peptide synthetase. (2519 aa)
BN6_32730AMP-dependent synthetase and ligase. (556 aa)
nrps5-a5Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family. (518 aa)
nrps5-4Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family. (1462 aa)
nrps5-3Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family. (1092 aa)
nrps5-2Non-ribosomal peptide synthetase. (1035 aa)
nrps5-1Non-ribosomal peptide synthetase. (1917 aa)
BN6_35920AMP-dependent synthetase and ligase. (487 aa)
BN6_37600AMP-dependent synthetase and ligase. (498 aa)
BN6_38310AMP-dependent synthetase and ligase. (500 aa)
nrps6Non-ribosomal peptide synthetase-like protein. (646 aa)
lcfBLong-chain-fatty-acid-CoA ligase. (497 aa)
BN6_40590AMP-dependent acetyl-coenzyme A synthetase and ligase. (546 aa)
nrps7Non-ribosomal peptide synthetase. (2098 aa)
nrps8Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family. (600 aa)
nrpks8Hybrid nonribosomal peptide synthetase / polyketide synthase. (2223 aa)
BN6_46240AMP-dependent synthetase and ligase. (500 aa)
nrps10-1Putative non-ribosomal peptide synthase. (2324 aa)
nrps10-a6Amino acid adenylation domain-containing protein. (484 aa)
nrps10-4Putative non-ribosomal peptide synthase. (963 aa)
nrps10-3Putative non-ribosomal peptide synthase. (1314 aa)
nrps10-2Amino acid adenylation domain-containing protein. (567 aa)
BN6_48510Acyl-CoA ligase. (528 aa)
BN6_48520Amide synthetase. (513 aa)
BN6_50250Putative long-chain-fatty-acid-CoA ligase. (504 aa)
BN6_50260Amide synthetase. (508 aa)
nrps12-1Non-ribosomal peptide synthetase. (2076 aa)
BN6_53050Non-ribosomal peptide synthetase. (988 aa)
nrps13Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family. (1559 aa)
nrps14-1Non-ribosomal peptide synthetase. (1918 aa)
nrps14-2Non-ribosomal peptide synthetase. (2093 aa)
nrps14-3Non-ribosomal peptide synthetase. (1109 aa)
nrps14-5Non-ribosomal peptide synthetase. (996 aa)
BN6_63880Putative acyl-CoA ligase. (450 aa)
BN6_64350Putative acyl-CoA synthetase. (554 aa)
BN6_78740Acyl-CoA synthetase. (441 aa)
menEPutative 2-succinylbenzoate-CoA ligase. (341 aa)
BN6_80900AMP-dependent synthetase and ligase. (489 aa)
BN6_81150Putative 4-coumarate-CoA ligase 3. (520 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
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