STRINGSTRING
aroB aroB trpC trpC BN6_35160 BN6_35160 sucC sucC trpE trpE BN6_39070 BN6_39070 BN6_40190 BN6_40190 BN6_48460 BN6_48460 BN6_54730 BN6_54730 BN6_56760 BN6_56760 sam5 sam5 sam8 sam8 pheA pheA glf glf fumC fumC trpB1 trpB1 entA entA BN6_34140 BN6_34140
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (368 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa)
BN6_35160Cytochrome P450 hydroxylase. (477 aa)
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (423 aa)
trpEAnthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (610 aa)
BN6_390704-hydroxyphenylacetate-3-hydroxylase. (518 aa)
BN6_40190Cytochrome P450 monooxygenase. (402 aa)
BN6_48460Cytochrome P450 monooxygenase. (414 aa)
BN6_54730Cytochrome P450 monooxygenase. (392 aa)
BN6_56760Cytochrome P450 monooxygenase. (416 aa)
sam54-coumarate 3-hydroxylase. (512 aa)
sam8Tyrosine ammonia-lyase. (510 aa)
pheAPrephenate dehydratase. (311 aa)
glfUDP-galactopyranose mutase. (394 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
trpB1Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa)
entA2,3-dihydro-2,3-dihydroxybenzoatedehydrogenase. (244 aa)
BN6_34140Cytochrome P450 monooxygenase. (382 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
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