STRINGSTRING
mutM1 mutM1 nth nth BN6_03790 BN6_03790 alkA1 alkA1 BN6_07480 BN6_07480 lig-2 lig-2 alkA3 alkA3 tag tag BN6_12820 BN6_12820 BN6_13500 BN6_13500 BN6_25200 BN6_25200 BN6_43400 BN6_43400 ligA1 ligA1 BN6_65930 BN6_65930 polA polA BN6_69370 BN6_69370 mutM3 mutM3 ung ung BN6_77620 BN6_77620 BN6_81740 BN6_81740 nfo nfo
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mutM1Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (287 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (255 aa)
BN6_03790HhH-GPD family protein. (289 aa)
alkA1Putative bifunctional transcriptional activator/DNA repair enzyme AlkA. (511 aa)
BN6_07480Hypothetical protein. (243 aa)
lig-2Putative DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (515 aa)
alkA3Putative bifunctional transcriptional activator/DNA repair enzyme AlkA. (448 aa)
tagDNA-3-methyladenine glycosylase I. (184 aa)
BN6_12820DNA-directed DNA polymerase. (556 aa)
BN6_13500Putative DNA glycosylase; Belongs to the FPG family. (267 aa)
BN6_25200G/U mismatch-specific DNA glycosylase. (171 aa)
BN6_43400Transcriptional regulator, AraC family. (458 aa)
ligA1DNA ligase 1; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (663 aa)
BN6_65930DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family. (208 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (889 aa)
BN6_69370Putative DNA glycosylase. (264 aa)
mutM3Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (216 aa)
BN6_77620Exodeoxyribonuclease III Xth. (327 aa)
BN6_81740Exodeoxyribonuclease III Xth. (338 aa)
nfoPutative endonuclease 4. (256 aa)
Your Current Organism:
Saccharothrix espanaensis
NCBI taxonomy Id: 1179773
Other names: S. espanaensis DSM 44229, Saccharothrix espanaensis ATCC 51144, Saccharothrix espanaensis DSM 44229, Saccharothrix espanaensis NRRL 15764, Saccharothrix espanaensis str. DSM 44229, Saccharothrix espanaensis strain DSM 44229
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