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ALS36845.1 ALS36845.1 rplA rplA rplJ rplJ rplL rplL ALS35709.1 ALS35709.1 prfC prfC kptA kptA ALS35661.1 ALS35661.1 gatC gatC gatA gatA gatB gatB ALS35628.1 ALS35628.1 ALS35624.1 ALS35624.1 ALS35607.1 ALS35607.1 ALS35606.1 ALS35606.1 ALS35605.1 ALS35605.1 ALS38709.1 ALS38709.1 ALS38698.1 ALS38698.1 ALS38681.1 ALS38681.1 ALS38679.1 ALS38679.1 ALS38641.1 ALS38641.1 trpS trpS ALS38624.1 ALS38624.1 ALS38618.1 ALS38618.1 ALS38847.1 ALS38847.1 ALS38582.1 ALS38582.1 ALS38581.1 ALS38581.1 smpB smpB ALS38546.1 ALS38546.1 ALS38510.1 ALS38510.1 prfA prfA ALS38473.1 ALS38473.1 ALS38374.1 ALS38374.1 lepA lepA tadA tadA ALS38303.1 ALS38303.1 ALS38300.1 ALS38300.1 ALS38299.1 ALS38299.1 ALS38298.1 ALS38298.1 tsaD tsaD argS argS ALS38259.1 ALS38259.1 ALS38255.1 ALS38255.1 rpsT rpsT rpsU rpsU ybeY ybeY glyQ glyQ glyS glyS ALS38203.1 ALS38203.1 ALS38202.1 ALS38202.1 rpsB rpsB tsf tsf frr frr proS proS ALS38168.1 ALS38168.1 pheS pheS pheT pheT ALS38157.1 ALS38157.1 ALS38130.1 ALS38130.1 rpoE rpoE tuf-2 tuf-2 sigA sigA rnz rnz ALS38080.1 ALS38080.1 rbgA rbgA gid gid cca cca ALS38012.1 ALS38012.1 ALS38004.1 ALS38004.1 rpsP rpsP pyrR pyrR ALS37964.1 ALS37964.1 ALS37956.1 ALS37956.1 ALS37934.1 ALS37934.1 rplS rplS trmD trmD rimM rimM ALS37890.1 ALS37890.1 ALS37832.1 ALS37832.1 ALS37818.1 ALS37818.1 rnj-2 rnj-2 rpmE2 rpmE2 rho rho asnC asnC ALS37762.1 ALS37762.1 ALS37750.1 ALS37750.1 alaS alaS tyrS tyrS prfB prfB ALS37599.1 ALS37599.1 ALS37564.1 ALS37564.1 rpsN-2 rpsN-2 ALS37526.1 ALS37526.1 ALS37518.1 ALS37518.1 aspS aspS hisS hisS ALS37453.1 ALS37453.1 rlmN rlmN ALS38792.1 ALS38792.1 mnmA mnmA ALS37390.1 ALS37390.1 miaA miaA ALS38786.1 ALS38786.1 ileS ileS rsmH rsmH nusB nusB rpmA rpmA rplU rplU ALS37244.1 ALS37244.1 ALS37239.1 ALS37239.1 rsmA rsmA rnmV rnmV metG metG rplT rplT rpmI rpmI infC infC ALS38778.1 ALS38778.1 tgt tgt ALS37154.1 ALS37154.1 queH queH ALS37121.1 ALS37121.1 ALS37107.1 ALS37107.1 ALS37085.1 ALS37085.1 rplY rplY ALS37071.1 ALS37071.1 leuS leuS ALS38774.1 ALS38774.1 lysS lysS ALS37029.1 ALS37029.1 tilS tilS ALS37024.1 ALS37024.1 pth pth ALS37012.1 ALS37012.1 efp efp truA-2 truA-2 rlmH rlmH ALS36902.1 ALS36902.1 trmB trmB ALS36889.1 ALS36889.1 ALS36880.1 ALS36880.1 ALS36877.1 ALS36877.1 ALS36858.1 ALS36858.1 ALS36768.1 ALS36768.1 ALS36708.1 ALS36708.1 rpsI rpsI rplM rplM ALS36687.1 ALS36687.1 rpoC rpoC rpoB rpoB birA birA serS serS rsmG rsmG mnmG mnmG mnmE mnmE rnpA rnpA rpmH rpmH rpsF rpsF rpsR rpsR rplI rplI ALS36555.1 ALS36555.1 ALS38756.1 ALS38756.1 gltX gltX cysS cysS mrnC mrnC ALS36492.1 ALS36492.1 ALS36490.1 ALS36490.1 ALS36446.1 ALS36446.1 ALS36445.1 ALS36445.1 ALS36419.1 ALS36419.1 rpoZ rpoZ def-2 def-2 fmt fmt ALS36411.1 ALS36411.1 rpmB rpmB rnc rnc ALS36359.1 ALS36359.1 ALS36358.1 ALS36358.1 rpsD rpsD def def rpsO rpsO pnp pnp ALS36322.1 ALS36322.1 ALS36321.1 ALS36321.1 ALS38741.1 ALS38741.1 rpsL rpsL rpsG rpsG fusA fusA tuf tuf rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO infA infA rpmJ rpmJ rpsM rpsM rpsK rpsK rpoA rpoA rplQ rplQ truA truA ALS36115.1 ALS36115.1 ALS36063.1 ALS36063.1 ALS36027.1 ALS36027.1 ALS35966.1 ALS35966.1 thiI thiI valS valS rnj rnj ALS35919.1 ALS35919.1 ALS35862.1 ALS35862.1 ALS35841.1 ALS35841.1 tmcAL tmcAL thrS thrS rpmG-2 rpmG-2 ALS35789.1 ALS35789.1 ALS35773.1 ALS35773.1 rsmI rsmI ALS35748.1 ALS35748.1 ALS35747.1 ALS35747.1 ALS35744.1 ALS35744.1 rpmG rpmG nusG nusG ALS35724.1 ALS35724.1 rplK rplK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ALS36845.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (229 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (166 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa)
ALS35709.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (456 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (525 aa)
kptARNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (185 aa)
ALS35661.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
gatCglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (101 aa)
gatAglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (489 aa)
gatBglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa)
ALS35628.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (457 aa)
ALS35624.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
ALS35607.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
ALS35606.1CoA-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
ALS35605.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
ALS38709.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (99 aa)
ALS38698.1ACT domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family. (89 aa)
ALS38681.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1298 aa)
ALS38679.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family. (313 aa)
ALS38641.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
trpStryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (338 aa)
ALS38624.1RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (297 aa)
ALS38618.1RNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (168 aa)
ALS38847.1CAAX protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
ALS38582.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (246 aa)
ALS38581.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (224 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (154 aa)
ALS38546.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
ALS38510.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (196 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (357 aa)
ALS38473.1Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (345 aa)
ALS38374.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
lepAElongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (611 aa)
tadADeaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (176 aa)
ALS38303.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ALS38300.1tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
ALS38299.1Ribosomal-protein-alanine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
ALS38298.1Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (154 aa)
tsaDtRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (344 aa)
argSarginine--tRNA ligase; Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
ALS38259.116S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
ALS38255.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (84 aa)
rpsU30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
ybeYrRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (158 aa)
glyQglycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
glySglycine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (693 aa)
ALS38203.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
ALS38202.123S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (257 aa)
rpsB30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (262 aa)
tsfElongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (293 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (570 aa)
ALS38168.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (181 aa)
pheSphenylalanine--tRNA ligase subunit alpha; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (348 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (807 aa)
ALS38157.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
ALS38130.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
rpoEDNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (210 aa)
tuf-2Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa)
sigARNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (368 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (310 aa)
ALS38080.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (184 aa)
rbgARibosome biogenesis GTPase YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (287 aa)
gidtRNA (uracil-5-)-methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (441 aa)
ccatRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (403 aa)
ALS38012.130S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ALS38004.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (238 aa)
rpsP30S ribosomal protein S16; Binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family. (91 aa)
pyrRUracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (185 aa)
ALS37964.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (301 aa)
ALS37956.1aminoacyl-tRNA deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (163 aa)
ALS37934.1Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (248 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (174 aa)
ALS37890.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily. (387 aa)
ALS37832.1Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (142 aa)
ALS37818.1Metallohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
rnj-2Zn-dependent hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (562 aa)
rpmE2RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may b [...] (89 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (430 aa)
asnCasparagine--tRNA ligase; Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ALS37762.1GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
ALS37750.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (879 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (327 aa)
ALS37599.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (225 aa)
ALS37564.1Adenine nucleotide alpha hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TtcA family. (251 aa)
rpsN-230S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa)
ALS37526.1Amidase; Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family. (486 aa)
ALS37518.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (202 aa)
aspSaspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (589 aa)
hisShistidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ALS37453.116S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (249 aa)
rlmN23S rRNA (adenine(2503)-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (356 aa)
ALS38792.1CMP deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
mnmAtRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa)
ALS37390.1RNA polymerase sigma-54 factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa)
ALS38786.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (1047 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (929 aa)
rsmHRibosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (319 aa)
nusBAntitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (149 aa)
rpmA50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family. (95 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
ALS37244.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
ALS37239.1tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
rsmA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (293 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (198 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (669 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
rpmI50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (173 aa)
ALS38778.1RNA-splicing ligase RtcB; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa)
ALS37154.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
queHDNA integration/recombination/inversion protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (241 aa)
ALS37121.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (280 aa)
ALS37107.1L-seryl-tRNA selenium transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ALS37085.116S rRNA pseudouridine(516) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (251 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (204 aa)
ALS37071.1Rhodanese; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (837 aa)
ALS38774.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (176 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (498 aa)
ALS37029.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (334 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (460 aa)
ALS37024.1RNA-binding protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (188 aa)
ALS37012.1Epoxyqueuosine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (187 aa)
truA-2tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (245 aa)
rlmH23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)
ALS36902.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (205 aa)
trmBtRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (218 aa)
ALS36889.13'-5' exonuclease; Catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
ALS36880.1RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (286 aa)
ALS36877.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
ALS36858.116S rRNA pseudouridine(516) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (240 aa)
ALS36768.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
ALS36708.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (320 aa)
rpsI30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
ALS36687.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1217 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1205 aa)
birAbiotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (328 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
rsmG16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (238 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (632 aa)
mnmEtRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (465 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (112 aa)
rpmH50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (100 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (150 aa)
ALS36555.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
ALS38756.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (180 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (485 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (470 aa)
mrnCMini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (132 aa)
ALS36492.1rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (279 aa)
ALS36490.1RNA polymerase subunit sigma-30; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (186 aa)
ALS36446.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (232 aa)
ALS36445.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (209 aa)
ALS36419.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (101 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (164 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (313 aa)
ALS36411.116S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (454 aa)
rpmB50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. (62 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (230 aa)
ALS36359.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
ALS36358.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (181 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (203 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (187 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (704 aa)
ALS36322.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (238 aa)
ALS36321.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (210 aa)
ALS38741.1RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (139 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (695 aa)
tufElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (209 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (207 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (115 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (218 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa)
rpmC50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (62 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (102 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (121 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa)
rpmD50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. (59 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpmJ50S ribosomal protein L36; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL36 family. (38 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (312 aa)
rplQ50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
truAPseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (248 aa)
ALS36115.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
ALS36063.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
ALS36027.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (202 aa)
ALS35966.1S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (401 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (881 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (556 aa)
ALS35919.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0356 family. (70 aa)
ALS35862.1General stress protein; Induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
ALS35841.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
tmcALHypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (389 aa)
thrSthreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (646 aa)
rpmG-250S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
ALS35789.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
ALS35773.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
rsmI16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (288 aa)
ALS35748.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
ALS35747.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ALS35744.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
rpmG50S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family. (50 aa)
nusGAntitermination protein NusG; Participates in transcription elongation, termination and antitermination. (180 aa)
ALS35724.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (286 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (140 aa)
Your Current Organism:
Enterococcus rotai
NCBI taxonomy Id: 118060
Other names: CCM 4630, CCUG 61593, E. rotai, Enterococcus rotai Sedlacek et al. 2013, Enterococcus sp. CCM 4360, LMG 26678, LMG:26678
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