(12 nodes) Helicase, C-terminal network (Enterococcus rotai)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	recG	ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (678 aa)
	priA	Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (810 aa)
	mfd	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1177 aa)
	cshA	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (513 aa)
	ALS37319.1	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
	ALS37650.1	Competence protein ComF; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
	secA	Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (843 aa)
	cshB	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (450 aa)
	dbpA	RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (482 aa)
	ALS38009.1	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
	ALS38637.1	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1065 aa)
	uvrB	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (664 aa)

Your Current Organism:

Enterococcus rotai

NCBI taxonomy Id: 118060
Other names: CCM 4630, CCUG 61593, E. rotai, Enterococcus rotai Sedlacek et al. 2013, Enterococcus sp. CCM 4360, LMG 26678, LMG:26678

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALS37319.1	ALS38009.1	ATZ35_09155	ATZ35_12910	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.813
ALS37319.1	ALS38637.1	ATZ35_09155	ATZ35_16225	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.743
ALS37319.1	cshB	ATZ35_09155	ATZ35_11465	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.	0.538
ALS38009.1	ALS37319.1	ATZ35_12910	ATZ35_09155	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.813
ALS38009.1	ALS38637.1	ATZ35_12910	ATZ35_16225	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
ALS38009.1	cshA	ATZ35_12910	ATZ35_08065	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.	0.942
ALS38009.1	cshB	ATZ35_12910	ATZ35_11465	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.	0.647
ALS38009.1	dbpA	ATZ35_12910	ATZ35_12490	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.	0.870
ALS38009.1	recG	ATZ35_12910	ATZ35_04230	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.	0.541
ALS38637.1	ALS37319.1	ATZ35_16225	ATZ35_09155	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.743
ALS38637.1	ALS38009.1	ATZ35_16225	ATZ35_12910	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
ALS38637.1	cshA	ATZ35_16225	ATZ35_08065	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.	0.741
ALS38637.1	cshB	ATZ35_16225	ATZ35_11465	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.	0.739
ALS38637.1	dbpA	ATZ35_16225	ATZ35_12490	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.	0.743
cshA	ALS38009.1	ATZ35_08065	ATZ35_12910	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
cshA	ALS38637.1	ATZ35_08065	ATZ35_16225	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.	Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.741
cshA	cshB	ATZ35_08065	ATZ35_11465	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.	0.459
cshA	dbpA	ATZ35_08065	ATZ35_12490	DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.	RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.	0.812
cshB	ALS37319.1	ATZ35_11465	ATZ35_09155	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538
cshB	ALS38009.1	ATZ35_11465	ATZ35_12910	DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.	Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.647