node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALS35707.1 | ALS35737.1 | ATZ35_00600 | ATZ35_00755 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
ALS35707.1 | ALS36596.1 | ATZ35_00600 | ATZ35_05295 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | 0.473 |
ALS35707.1 | ALS38090.1 | ATZ35_00600 | ATZ35_13330 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.499 |
ALS35707.1 | mutM | ATZ35_00600 | ATZ35_14635 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.514 |
ALS35707.1 | nth | ATZ35_00600 | ATZ35_12265 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.661 |
ALS35707.1 | polA | ATZ35_00600 | ATZ35_14640 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.529 |
ALS35737.1 | ALS35707.1 | ATZ35_00755 | ATZ35_00600 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.962 |
ALS35737.1 | ALS36596.1 | ATZ35_00755 | ATZ35_05295 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | 0.455 |
ALS35737.1 | ALS38090.1 | ATZ35_00755 | ATZ35_13330 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.463 |
ALS35737.1 | nfo | ATZ35_00755 | ATZ35_11200 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.923 |
ALS35737.1 | nth | ATZ35_00755 | ATZ35_12265 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.995 |
ALS35737.1 | polA | ATZ35_00755 | ATZ35_14640 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.986 |
ALS35737.1 | ung | ATZ35_00755 | ATZ35_08720 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.921 |
ALS36009.1 | ALS36804.1 | ATZ35_02195 | ATZ35_06435 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
ALS36009.1 | ALS38821.1 | ATZ35_02195 | ATZ35_12790 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
ALS36009.1 | polA | ATZ35_02195 | ATZ35_14640 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.522 |
ALS36596.1 | ALS35707.1 | ATZ35_05295 | ATZ35_00600 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.473 |
ALS36596.1 | ALS35737.1 | ATZ35_05295 | ATZ35_00755 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.455 |
ALS36596.1 | ALS37802.1 | ATZ35_05295 | ATZ35_11775 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.485 |
ALS36596.1 | ALS38090.1 | ATZ35_05295 | ATZ35_13330 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. | single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.492 |