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pdtaR1 pdtaR1 pdtaS1 pdtaS1 MCBB_0286 MCBB_0286 pdtaS3 pdtaS3 MCBB_0628 MCBB_0628 pdtaS7 pdtaS7 MCBB_0916 MCBB_0916 yhdG yhdG pdtaR3 pdtaR3 MCBB_1258 MCBB_1258 msmS msmS pdtaR5 pdtaR5 pdtaS11 pdtaS11 HK1 HK1 MCBB_1550 MCBB_1550 aphA1 aphA1 phyR phyR filI filI pdtaS13 pdtaS13 MCBB_1773 MCBB_1773 pdtaS15 pdtaS15 dhaT dhaT pdtaR7 pdtaR7 MCBB_2059 MCBB_2059 pdtaS17 pdtaS17 MCBB_2064 MCBB_2064 pdtaS19 pdtaS19 MCBB_2315 MCBB_2315 MCBB_2353 MCBB_2353
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pdtaR1Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-011; PctID=35.64; score=70.1. (250 aa)
pdtaS1Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-021; PctID=33.33; score=105. (932 aa)
MCBB_0286Putative PAS/PAC sensor protein; tr|F6D3Z3|F6D3Z3_METPW;evalue=0.0; PctID=70.80; score=732; {ECO:0000313|EMBL:AEG19170,1}. (715 aa)
pdtaS3Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-018; PctID=28.02; score=93.2. (331 aa)
MCBB_0628Signal transduction histidine kinase; tr|F0T978|F0T978_METLA;evalue=7e-106; PctID=60.21; score=391; {ECO:0000313|EMBL:ADZ08700,1}. (572 aa)
pdtaS7Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=7e-024; PctID=30.45; score=113. (814 aa)
MCBB_0916Signal transduction histidine kinase; tr|F0T830|F0T830_METLA;evalue=1e-132; PctID=47.90; score=480; {ECO:0000313|EMBL:ADZ09656,1}. (583 aa)
yhdGPutative amino acid permease YhdG; sp|O07576|YHDG_BACSU;evalue=1e-121; PctID=47.20; score=437. (467 aa)
pdtaR3Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=9e-016; PctID=31.88; score=85.1. (418 aa)
MCBB_1258Putative protein AZC_3085; sp|Q04855|Y3085_AZOC5;evalue=3e-013; PctID=31.97; score=78.2. (850 aa)
msmSHeme-binding sensor kinase component part of a two-component regulatory system involved in methyl sulfide metabolism. Does not act as a phytochrome-like photoreceptor. phospho-L-histidine. Name=heme; Xref=ChEBI:CHEBI:30413; Evidence=; Note=Heme-binding is redox-active and coordinates various ligands such as imidazole, dimethyl sulfide, and carbon monoxide depending on the redox state. The redox state of the heme cofactor influences on autophosphorylation activity: while reduced protein does not autophosphorylate, oxidized protein promotes autophosphorylation signal; redox state of heme [...] (751 aa)
pdtaR5Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=4e-011; PctID=31.90; score=68.9. (280 aa)
pdtaS11Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=1e-016; PctID=28.40; score=89.0. (673 aa)
HK1Putative histidine kinase 1; Cytokinin receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. phospho-L-histidine. an active histidine that mediates the phosphotransfer. between a His in the transmitter domain and an Asp of the receiver domain. Sequence=BAD37425.1; Type=Erroneous gene model prediction; Evidence=; Sequence=BAD37547.1; Type=Erroneous gene model prediction; Evidence=; Sequence=BAF20158.1; Type=Erroneous gene model prediction; Evidence=; sp|A2YFR6|OHK1_ORYSI,sp|A3BE68|OHK1_ORYSJ; [...] (140 aa)
MCBB_1550CheY-like receiver domain-containing protein; tr|K6T239|K6T239_9EURY;evalue=5e-013; PctID=36.96; score=79.3; {ECO:0000313|EMBL:EKQ53248,1}. (106 aa)
aphA1Cyanobacterial phytochrome A; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. phospho-L-histidine. family; sp|Q9LCC2|PHYA_NOSS1;evalue=2e-065; PctID=52.65; score=250. (536 aa)
phyRPhyllosphere-induced regulator PhyR; Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE, sodA, hsp20, dps and gloA. However,it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases. is the same as in the wild-type strain when plant colonization is mimicked in vitro in the presence of succinate and methanol. However, in planta colonization experiments show a severe growth defect of the phyR deletion mutant. Sequence=ACS40857.1; Type=Erroneous initiation; Evidence=; [...] (121 aa)
filIMethanogenesis regulatory histidine kinase FilI; Could also catalyze the synthesis of the quorum sensing (QS) signal molecules carboxyl-acyl homoserine lactones (AHLs), which regulate the transition of the cellular morphology from short cells to filaments and of the carbon metabolic flux from biomass formation to methane production. phospho-L-histidine. Multi-pass membrane protein Transcript level increases with cell density. ProRule:PRU00102}; sp|E5KK10|FILI_METH6;evalue=6e-010; PctID=31.54; score=66.2; {ECO:0000305}. (548 aa)
pdtaS13Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=6e-021; PctID=33.18; score=102. (562 aa)
MCBB_1773Putative protein; tr|F0T9K7|F0T9K7_METLA;evalue=1e-139; PctID=60.85; score=503; {ECO:0000313|EMBL:ADZ08755,1}. (415 aa)
pdtaS15Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=1e-016; PctID=30.43; score=87.8. (373 aa)
dhaT1,3-propanediol dehydrogenase; Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate. + NADH. Name=Fe cation; Xref=ChEBI:CHEBI:24875; family; sp|P45513|DHAT_CITFR;evalue=4e-074; PctID=37.20; score=278. (388 aa)
pdtaR7Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-014; PctID=35.77; score=83.2. (1022 aa)
MCBB_2059UPF0118 membrane protein; sp|O27279|Y1211_METTH;evalue=4e-069; PctID=53.39; score=262. (367 aa)
pdtaS17Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-023; PctID=33.02; score=110. (471 aa)
MCBB_2064Putative protein; tr|F6D3F1|F6D3F1_METPW;evalue=3e-023; PctID=82.35; score=113; {ECO:0000313|EMBL:AEG19127,1}. (93 aa)
pdtaS19Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=3e-019; PctID=31.67; score=97.1. (570 aa)
MCBB_2315Hypothetical protein. (77 aa)
MCBB_2353PAS domain S-box; tr|K6U9S1|K6U9S1_9EURY;evalue=5e-069; PctID=43.84; score=269; {ECO:0000313|EMBL:EKQ54049,1}. (756 aa)
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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