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MCBB_0286 MCBB_0286 MCBB_0292 MCBB_0292 pdtaS3 pdtaS3 MCBB_0628 MCBB_0628 pdtaS5 pdtaS5 MCBB_0916 MCBB_0916 pdtaR3 pdtaR3 MCBB_1258 MCBB_1258 pdtaS9 pdtaS9 msmS msmS pdtaS11 pdtaS11 aphA1 aphA1 filI filI pdtaR7 pdtaR7 aphA3 aphA3 MCBB_2353 MCBB_2353 pdtaS1 pdtaS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
MCBB_0286Putative PAS/PAC sensor protein; tr|F6D3Z3|F6D3Z3_METPW;evalue=0.0; PctID=70.80; score=732; {ECO:0000313|EMBL:AEG19170,1}. (715 aa)
MCBB_0292GAF domain protein; tr|F6D219|F6D219_METPW;evalue=5e-174; PctID=60.33; score=617; {ECO:0000313|EMBL:AEG17308,1}. (536 aa)
pdtaS3Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-018; PctID=28.02; score=93.2. (331 aa)
MCBB_0628Signal transduction histidine kinase; tr|F0T978|F0T978_METLA;evalue=7e-106; PctID=60.21; score=391; {ECO:0000313|EMBL:ADZ08700,1}. (572 aa)
pdtaS5Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=4e-017; PctID=31.94; score=91.3. (991 aa)
MCBB_0916Signal transduction histidine kinase; tr|F0T830|F0T830_METLA;evalue=1e-132; PctID=47.90; score=480; {ECO:0000313|EMBL:ADZ09656,1}. (583 aa)
pdtaR3Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=9e-016; PctID=31.88; score=85.1. (418 aa)
MCBB_1258Putative protein AZC_3085; sp|Q04855|Y3085_AZOC5;evalue=3e-013; PctID=31.97; score=78.2. (850 aa)
pdtaS9Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-020; PctID=32.98; score=102. (750 aa)
msmSHeme-binding sensor kinase component part of a two-component regulatory system involved in methyl sulfide metabolism. Does not act as a phytochrome-like photoreceptor. phospho-L-histidine. Name=heme; Xref=ChEBI:CHEBI:30413; Evidence=; Note=Heme-binding is redox-active and coordinates various ligands such as imidazole, dimethyl sulfide, and carbon monoxide depending on the redox state. The redox state of the heme cofactor influences on autophosphorylation activity: while reduced protein does not autophosphorylate, oxidized protein promotes autophosphorylation signal; redox state of heme [...] (751 aa)
pdtaS11Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=1e-016; PctID=28.40; score=89.0. (673 aa)
aphA1Cyanobacterial phytochrome A; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. phospho-L-histidine. family; sp|Q9LCC2|PHYA_NOSS1;evalue=2e-065; PctID=52.65; score=250. (536 aa)
filIMethanogenesis regulatory histidine kinase FilI; Could also catalyze the synthesis of the quorum sensing (QS) signal molecules carboxyl-acyl homoserine lactones (AHLs), which regulate the transition of the cellular morphology from short cells to filaments and of the carbon metabolic flux from biomass formation to methane production. phospho-L-histidine. Multi-pass membrane protein Transcript level increases with cell density. ProRule:PRU00102}; sp|E5KK10|FILI_METH6;evalue=6e-010; PctID=31.54; score=66.2; {ECO:0000305}. (548 aa)
pdtaR7Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-014; PctID=35.77; score=83.2. (1022 aa)
aphA3Cyanobacterial phytochrome A; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. phospho-L-histidine. family; sp|Q9LCC2|PHYA_NOSS1;evalue=3e-037; PctID=36.96; score=157. (761 aa)
MCBB_2353PAS domain S-box; tr|K6U9S1|K6U9S1_9EURY;evalue=5e-069; PctID=43.84; score=269; {ECO:0000313|EMBL:EKQ54049,1}. (756 aa)
pdtaS1Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-021; PctID=33.33; score=105. (932 aa)
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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