STRINGSTRING
AFY76568.1 AFY76568.1 ilvC ilvC murB murB AFY79510.1 AFY79510.1 zwf zwf AFY79278.1 AFY79278.1 hisD-2 hisD-2 AFY79155.1 AFY79155.1 hisD hisD AFY78616.1 AFY78616.1 fcl fcl aroE aroE ldh ldh AFY78362.1 AFY78362.1 AFY78358.1 AFY78358.1 AFY78306.1 AFY78306.1 AFY78301.1 AFY78301.1 AFY78135.1 AFY78135.1 pdxA pdxA AFY77803.1 AFY77803.1 AFY77742.1 AFY77742.1 AFY77455.1 AFY77455.1 AFY77360.1 AFY77360.1 mdh mdh AFY77245.1 AFY77245.1 AFY77022.1 AFY77022.1 AFY76911.1 AFY76911.1 dxr dxr AFY75821.1 AFY75821.1 leuB leuB AFY76031.1 AFY76031.1 gpsA gpsA AFY76312.1 AFY76312.1 AFY76319.1 AFY76319.1 AFY76449.1 AFY76449.1 AFY76479.1 AFY76479.1 AFY76534.1 AFY76534.1 AFY76555.1 AFY76555.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
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Your Input:
AFY76568.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (245 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (309 aa)
AFY79510.1Zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES-like domain. (330 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa)
AFY79278.1Pyrimidine reductase, riboflavin biosynthesis; PFAM: RibD C-terminal domain. (274 aa)
hisD-2Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
AFY79155.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (266 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
AFY78616.1Glycerol dehydrogenase-like oxidoreductase; PFAM: Iron-containing alcohol dehydrogenase. (376 aa)
fclNucleoside-diphosphate-sugar epimerase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (312 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (366 aa)
AFY78362.1Putative oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: Aldo/keto reductase family. (326 aa)
AFY78358.1PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (800 aa)
AFY78306.1Isocitrate dehydrogenase, NADP-dependent, prokaryotic type; PFAM: Isocitrate/isopropylmalate dehydrogenase. (475 aa)
AFY78301.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (377 aa)
AFY78135.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (333 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (361 aa)
AFY77803.1PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase. (349 aa)
AFY77742.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (432 aa)
AFY77455.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (473 aa)
AFY77360.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (297 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (333 aa)
AFY77245.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; ACT domain. (463 aa)
AFY77022.1Alcohol dehydrogenase, class IV; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (893 aa)
AFY76911.1PFAM: NAD dependent epimerase/dehydratase family. (354 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (397 aa)
AFY75821.1PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase. (326 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (366 aa)
AFY76031.1Hopanoid-associated sugar epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase. (328 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (314 aa)
AFY76312.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (333 aa)
AFY76319.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (526 aa)
AFY76449.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase. (462 aa)
AFY76479.13-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
AFY76534.1dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase. (292 aa)
AFY76555.1PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein. (389 aa)
Your Current Organism:
Pleurocapsa sp. PCC7327
NCBI taxonomy Id: 118163
Other names: P. sp. PCC 7327, Pleurocapsa minor OH-69-pm, Pleurocapsa sp. ATCC 29393, Pleurocapsa sp. PCC 7327
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