(69 nodes) Progesterone-mediated oocyte maturation network (Picoides pubescens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N307_01730	Adenylate cyclase type 1. (1090 aa)
	N307_14735	Ribosomal protein S6 kinase 2 alpha. (725 aa)
	N307_13642	Putative peptidyl-tRNA hydrolase PTRHD1. (144 aa)
	N307_01924	Serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. (349 aa)
	N307_09653	Cyclin-A1; Belongs to the cyclin family. (317 aa)
	N307_01039	Guanine nucleotide-binding protein G(K) subunit alpha. (252 aa)
	N307_02243	Mitotic checkpoint serine/threonine-protein kinase BUB1. (1079 aa)
	N307_00305	GTP-binding protein RAD. (203 aa)
	N307_05772	Phosphatidylinositol 3-kinase regulatory subunit beta. (721 aa)
	N307_05432	Adenylate cyclase type 6. (87 aa)
	N307_13274	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (836 aa)
	N307_13421	Mitogen-activated protein kinase. (323 aa)
	N307_13327	Insulin-like growth factor I. (133 aa)
	N307_15130	Mitotic spindle assembly checkpoint protein MAD2A. (206 aa)
	N307_03899	Transmembrane protein 82. (205 aa)
	N307_03832	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (465 aa)
	N307_10104	Mitogen-activated protein kinase. (424 aa)
	N307_00886	Anaphase-promoting complex subunit 7. (565 aa)
	N307_13640	Adenylate cyclase type 3. (1154 aa)
	N307_02639	Phosphatidylinositol 3-kinase regulatory subunit alpha. (724 aa)
	N307_14854	Guanine nucleotide-binding protein G(I) subunit alpha-2. (315 aa)
	N307_01437	Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
	N307_14513	Anaphase-promoting complex subunit 13. (43 aa)
	N307_04294	Ribosomal protein S6 kinase alpha-2. (549 aa)
	N307_01574	Serine/threonine-protein kinase PLK1. (455 aa)
	N307_06237	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1069 aa)
	N307_13787	Cytoplasmic polyadenylation element-binding protein 4. (734 aa)
	N307_05387	G2/mitotic-specific cyclin-B3. (190 aa)
	N307_12637	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (107 aa)
	N307_12987	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (946 aa)
	N307_00458	Cyclin-dependent kinase 1. (280 aa)
	N307_09408	Mitogen-activated protein kinase. (299 aa)
	N307_01462	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1044 aa)
	N307_11797	RAC-gamma serine/threonine-protein kinase. (248 aa)
	N307_05496	RAF proto-oncogene serine/threonine-protein kinase. (647 aa)
	N307_00719	Cell division cycle protein 23. (584 aa)
	N307_02850	GTP-binding protein GEM. (155 aa)
	N307_13509	Phosphodiesterase. (923 aa)
	N307_13275	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (450 aa)
	N307_09407	Mitogen-activated protein kinase. (320 aa)
	N307_02675	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (368 aa)
	N307_00550	M-phase inducer phosphatase 1. (517 aa)
	N307_05300	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	N307_07244	Cell division cycle protein 16. (623 aa)
	N307_12207	Serine/threonine-protein kinase B-raf. (760 aa)
	N307_00254	Cytoplasmic polyadenylation element-binding protein 1. (562 aa)
	N307_06174	Cytoplasmic polyadenylation element-binding protein 3. (687 aa)
	N307_04778	Phosphatidylinositol 3-kinase regulatory subunit alpha. (722 aa)
	N307_08608	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	N307_06961	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	N307_04440	Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (887 aa)
	N307_06523	G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (389 aa)
	N307_14336	Adenylate cyclase type 2. (1086 aa)
	N307_06121	Mitogen-activated protein kinase. (427 aa)
	N307_11980	Fizzy-related protein. (487 aa)
	N307_13196	Progesterone receptor. (402 aa)
	N307_06897	Ribosomal protein S6 kinase alpha-6. (699 aa)
	N307_10583	Anaphase-promoting complex subunit 2; Belongs to the cullin family. (783 aa)
	N307_10260	Speedy protein A. (310 aa)
	N307_13137	Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (283 aa)
	N307_03868	Heat shock protein HSP 90-alpha. (728 aa)
	N307_15137	Cyclin-A2; Belongs to the cyclin family. (301 aa)
	N307_13420	Mitogen-activated protein kinase. (312 aa)
	N307_07742	Mitotic spindle assembly checkpoint protein MAD1. (532 aa)
	N307_14005	M-phase inducer phosphatase 2. (183 aa)
	N307_00468	Mitogen-activated protein kinase 10. (334 aa)
	N307_05404	Cell division cycle protein 27. (822 aa)
	N307_02401	Guanine nucleotide-binding protein G(I) subunit alpha-1. (365 aa)
	N307_14006	AP-5 complex subunit sigma-1. (137 aa)

Your Current Organism:

Picoides pubescens

NCBI taxonomy Id: 118200
Other names: Dendrocopos pubescens, Downy woodpecker, Dryobates pubescens, P. pubescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N307_00254	N307_00458	A0A093GFQ7	A0A093GQH8	Cytoplasmic polyadenylation element-binding protein 1.	Cyclin-dependent kinase 1.	0.885
N307_00254	N307_01574	A0A093GFQ7	A0A093GVI3	Cytoplasmic polyadenylation element-binding protein 1.	Serine/threonine-protein kinase PLK1.	0.884
N307_00254	N307_01924	A0A093GFQ7	A0A093ITQ8	Cytoplasmic polyadenylation element-binding protein 1.	Serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily.	0.412
N307_00254	N307_05387	A0A093GFQ7	A0A093GTU7	Cytoplasmic polyadenylation element-binding protein 1.	G2/mitotic-specific cyclin-B3.	0.662
N307_00254	N307_06174	A0A093GFQ7	A0A093GEN2	Cytoplasmic polyadenylation element-binding protein 1.	Cytoplasmic polyadenylation element-binding protein 3.	0.873
N307_00254	N307_06523	A0A093GFQ7	A0A093G9F4	Cytoplasmic polyadenylation element-binding protein 1.	G2/mitotic-specific cyclin-B2; Belongs to the cyclin family.	0.867
N307_00254	N307_07244	A0A093GFQ7	A0A093GGD6	Cytoplasmic polyadenylation element-binding protein 1.	Cell division cycle protein 16.	0.673
N307_00254	N307_13137	A0A093GFQ7	A0A093G5F7	Cytoplasmic polyadenylation element-binding protein 1.	Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily.	0.664
N307_00254	N307_13787	A0A093GFQ7	A0A093GU02	Cytoplasmic polyadenylation element-binding protein 1.	Cytoplasmic polyadenylation element-binding protein 4.	0.882
N307_00305	N307_00468	A0A093IMB6	A0A093FYQ9	GTP-binding protein RAD.	Mitogen-activated protein kinase 10.	0.519
N307_00305	N307_01462	A0A093IMB6	A0A093GPR6	GTP-binding protein RAD.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	0.543
N307_00305	N307_01574	A0A093IMB6	A0A093GVI3	GTP-binding protein RAD.	Serine/threonine-protein kinase PLK1.	0.409
N307_00305	N307_01924	A0A093IMB6	A0A093ITQ8	GTP-binding protein RAD.	Serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily.	0.653
N307_00305	N307_02639	A0A093IMB6	A0A093H373	GTP-binding protein RAD.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.447
N307_00305	N307_02675	A0A093IMB6	A0A093GI41	GTP-binding protein RAD.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.561
N307_00305	N307_03832	A0A093IMB6	A0A093I5D6	GTP-binding protein RAD.	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.480
N307_00305	N307_03868	A0A093IMB6	A0A093G5E8	GTP-binding protein RAD.	Heat shock protein HSP 90-alpha.	0.582
N307_00305	N307_04778	A0A093IMB6	A0A093GE76	GTP-binding protein RAD.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.447
N307_00305	N307_05300	A0A093IMB6	A0A093GHE1	GTP-binding protein RAD.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.543
N307_00305	N307_05496	A0A093IMB6	A0A093GP33	GTP-binding protein RAD.	RAF proto-oncogene serine/threonine-protein kinase.	0.605