(25 nodes) Histone methylation network (Capronia coronata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A1O1_04126	Post-SET domain-containing protein. (202 aa)
	A1O1_08808	WD_REPEATS_REGION domain-containing protein. (550 aa)
	A1O1_08863	Uncharacterized protein. (377 aa)
	A1O1_09071	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1281 aa)
	A1O1_06690	Uncharacterized protein. (817 aa)
	A1O1_07055	WD_REPEATS_REGION domain-containing protein. (496 aa)
	A1O1_08716	SET domain-containing protein. (94 aa)
	A1O1_06435	WD_REPEATS_REGION domain-containing protein. (416 aa)
	A1O1_04094	Uncharacterized protein. (1638 aa)
	A1O1_04252	Histone-lysine N-methyltransferase ASH1L. (779 aa)
	A1O1_03598	Uncharacterized protein. (547 aa)
	A1O1_05171	Histone-lysine N-methyltransferase SETD2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (1023 aa)
	A1O1_03734	Uncharacterized protein. (493 aa)
	A1O1_02516	SET domain-containing protein. (443 aa)
	A1O1_02586	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (539 aa)
	A1O1_04463	SET domain-containing protein. (773 aa)
	A1O1_00227	rRNA 2'-O-methyltransferase fibrillarin. (247 aa)
	A1O1_01017	Uncharacterized protein. (831 aa)
	A1O1_00917	Uncharacterized protein. (1463 aa)
	A1O1_02749	Protein arginine N-methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (904 aa)
	A1O1_02896	WD_REPEATS_REGION domain-containing protein. (353 aa)
	A1O1_02987	HAD_SAK_1 domain-containing protein. (585 aa)
	A1O1_00777	Uncharacterized protein. (669 aa)
	A1O1_00492	WD_REPEATS_REGION domain-containing protein. (392 aa)
	A1O1_03979	SET domain-containing protein. (618 aa)

Your Current Organism:

Capronia coronata

NCBI taxonomy Id: 1182541
Other names: C. coronata CBS 617.96, Capronia coronata CBS 617.96

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O1_00227	A1O1_02749	W9YRC6	W9YXH3	rRNA 2'-O-methyltransferase fibrillarin.	Protein arginine N-methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.729
A1O1_00492	A1O1_00777	W9Z1E5	W9Z123	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.484
A1O1_00492	A1O1_00917	W9Z1E5	W9YTB9	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.414
A1O1_00492	A1O1_01017	W9Z1E5	W9YSP2	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.964
A1O1_00492	A1O1_02516	W9Z1E5	W9YNJ1	WD_REPEATS_REGION domain-containing protein.	SET domain-containing protein.	0.484
A1O1_00492	A1O1_02749	W9Z1E5	W9YXH3	WD_REPEATS_REGION domain-containing protein.	Protein arginine N-methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.585
A1O1_00492	A1O1_02896	W9Z1E5	W9YXV2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.908
A1O1_00492	A1O1_03598	W9Z1E5	W9YLE8	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.988
A1O1_00492	A1O1_03979	W9Z1E5	W9Z8Q7	WD_REPEATS_REGION domain-containing protein.	SET domain-containing protein.	0.484
A1O1_00492	A1O1_04094	W9Z1E5	W9YDN4	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.718
A1O1_00492	A1O1_05171	W9Z1E5	W9YG47	WD_REPEATS_REGION domain-containing protein.	Histone-lysine N-methyltransferase SETD2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.519
A1O1_00492	A1O1_06435	W9Z1E5	W9Y9Z1	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.423
A1O1_00492	A1O1_06690	W9Z1E5	W9XR93	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.499
A1O1_00492	A1O1_07055	W9Z1E5	W9XSB4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.997
A1O1_00492	A1O1_08863	W9Z1E5	W9XE51	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.484
A1O1_00492	A1O1_09071	W9Z1E5	W9XMV9	WD_REPEATS_REGION domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.993
A1O1_00777	A1O1_00492	W9Z123	W9Z1E5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.484
A1O1_00777	A1O1_00917	W9Z123	W9YTB9	Uncharacterized protein.	Uncharacterized protein.	0.605
A1O1_00777	A1O1_01017	W9Z123	W9YSP2	Uncharacterized protein.	Uncharacterized protein.	0.435
A1O1_00777	A1O1_02586	W9Z123	W9YNQ3	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.863