(37 nodes) Cortical cytoskeleton organization network (Capronia coronata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A1O1_08710	Uncharacterized protein. (914 aa)
	A1O1_04903	Uncharacterized protein. (207 aa)
	A1O1_07986	MHD domain-containing protein. (873 aa)
	A1O1_01141	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	A1O1_03769	Uncharacterized protein. (671 aa)
	A1O1_01930	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
	A1O1_02300	Uncharacterized protein. (147 aa)
	A1O1_02605	Uncharacterized protein. (430 aa)
	A1O1_04097	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (320 aa)
	A1O1_04325	Chitin synthase 1. (1129 aa)
	A1O1_07548	Myosin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1335 aa)
	A1O1_04356	Profilin; Belongs to the profilin family. (150 aa)
	A1O1_02964	Actin-like protein 3; Belongs to the actin family. (402 aa)
	A1O1_03105	DUF2013 domain-containing protein. (887 aa)
	A1O1_01022	NAK protein kinase. (992 aa)
	A1O1_05808	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
	A1O1_01603	Uncharacterized protein. (165 aa)
	A1O1_01344	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	A1O1_06569	GTP-binding protein rhoA. (193 aa)
	A1O1_02384	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (146 aa)
	A1O1_00497	Uncharacterized protein. (506 aa)
	A1O1_01162	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (391 aa)
	A1O1_08471	Uncharacterized protein. (436 aa)
	A1O1_08179	Uncharacterized protein. (766 aa)
	A1O1_08616	Actin, gamma. (375 aa)
	A1O1_08561	Cytokinesis protein. (1805 aa)
	A1O1_08711	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	A1O1_06842	Uncharacterized protein. (423 aa)
	A1O1_08463	GTP-binding protein rhoC. (279 aa)
	A1O1_07962	Uncharacterized protein. (1060 aa)
	A1O1_09082	Uncharacterized protein. (252 aa)
	A1O1_06790	Cell division cycle 14. (667 aa)
	A1O1_04895	GTP-binding protein rho2. (202 aa)
	A1O1_05387	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1279 aa)
	A1O1_05669	Uncharacterized protein. (1166 aa)
	A1O1_06491	GTP-binding protein RHO3. (202 aa)
	A1O1_04605	Uncharacterized protein. (999 aa)

Your Current Organism:

Capronia coronata

NCBI taxonomy Id: 1182541
Other names: C. coronata CBS 617.96, Capronia coronata CBS 617.96

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O1_00497	A1O1_01162	W9Z1E8	W9Z379	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.577
A1O1_00497	A1O1_01603	W9Z1E8	W9YUA0	Uncharacterized protein.	Uncharacterized protein.	0.526
A1O1_00497	A1O1_02300	W9Z1E8	W9YLZ7	Uncharacterized protein.	Uncharacterized protein.	0.464
A1O1_00497	A1O1_02964	W9Z1E8	W9YPT8	Uncharacterized protein.	Actin-like protein 3; Belongs to the actin family.	0.574
A1O1_00497	A1O1_04356	W9Z1E8	W9YPS4	Uncharacterized protein.	Profilin; Belongs to the profilin family.	0.844
A1O1_00497	A1O1_04605	W9Z1E8	W9YEI7	Uncharacterized protein.	Uncharacterized protein.	0.836
A1O1_00497	A1O1_04895	W9Z1E8	W9Y614	Uncharacterized protein.	GTP-binding protein rho2.	0.751
A1O1_00497	A1O1_04903	W9Z1E8	W9YFF2	Uncharacterized protein.	Uncharacterized protein.	0.751
A1O1_00497	A1O1_05387	W9Z1E8	W9Y6J7	Uncharacterized protein.	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.449
A1O1_00497	A1O1_05669	W9Z1E8	W9Y7B6	Uncharacterized protein.	Uncharacterized protein.	0.552
A1O1_00497	A1O1_06491	W9Z1E8	W9YA35	Uncharacterized protein.	GTP-binding protein RHO3.	0.751
A1O1_00497	A1O1_06569	W9Z1E8	W9YV93	Uncharacterized protein.	GTP-binding protein rhoA.	0.854
A1O1_00497	A1O1_06790	W9Z1E8	W9Y1P6	Uncharacterized protein.	Cell division cycle 14.	0.411
A1O1_00497	A1O1_07548	W9Z1E8	W9YNT6	Uncharacterized protein.	Myosin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.562
A1O1_00497	A1O1_08463	W9Z1E8	W9XSK5	Uncharacterized protein.	GTP-binding protein rhoC.	0.840
A1O1_00497	A1O1_08616	W9Z1E8	W9XU12	Uncharacterized protein.	Actin, gamma.	0.799
A1O1_01022	A1O1_01344	W9YSP7	W9YUL5	NAK protein kinase.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.867
A1O1_01022	A1O1_04605	W9YSP7	W9YEI7	NAK protein kinase.	Uncharacterized protein.	0.731
A1O1_01022	A1O1_05387	W9YSP7	W9Y6J7	NAK protein kinase.	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.423
A1O1_01022	A1O1_05669	W9YSP7	W9Y7B6	NAK protein kinase.	Uncharacterized protein.	0.581