(28 nodes) Terpenoid backbone biosynthesis network (Capronia coronata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	A1O1_01661	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (390 aa)
	A1O1_07938	Undecaprenyl diphosphate synthase. (425 aa)
	A1O1_06916	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1149 aa)
	A1O1_06196	Prenylcys_lyase domain-containing protein. (599 aa)
	A1O1_04678	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (436 aa)
	A1O1_04844	Uncharacterized protein. (865 aa)
	A1O1_09186	Isopentenyl-diphosphate delta-isomerase. (278 aa)
	A1O1_03342	Hexaprenyl pyrophosphate synthase, mitochondrial; Belongs to the FPP/GGPP synthase family. (459 aa)
	A1O1_04580	Abhydrolase_3 domain-containing protein. (172 aa)
	A1O1_04843	Uncharacterized protein. (586 aa)
	A1O1_05351	Uncharacterized protein. (379 aa)
	A1O1_05582	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	A1O1_01949	Prenyl protein peptidase. (331 aa)
	A1O1_02325	Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (347 aa)
	A1O1_06940	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1027 aa)
	A1O1_03048	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (464 aa)
	A1O1_04482	Uncharacterized protein. (425 aa)
	A1O1_02909	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (468 aa)
	A1O1_03221	Mitochondrial import receptor subunit tom-70. (625 aa)
	A1O1_01278	Uncharacterized protein. (369 aa)
	A1O1_01328	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (491 aa)
	A1O1_06278	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (398 aa)
	A1O1_00512	Peptidase_M48 domain-containing protein. (373 aa)
	A1O1_02835	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (462 aa)
	A1O1_00097	Uncharacterized protein. (424 aa)
	A1O1_00273	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (290 aa)
	A1O1_00726	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (868 aa)
	A1O1_01350	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (476 aa)

Your Current Organism:

Capronia coronata

NCBI taxonomy Id: 1182541
Other names: C. coronata CBS 617.96, Capronia coronata CBS 617.96

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O1_00097	A1O1_01661	W9ZKE9	W9ZFH1	Uncharacterized protein.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.761
A1O1_00097	A1O1_02325	W9ZKE9	W9YM16	Uncharacterized protein.	Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.761
A1O1_00097	A1O1_03342	W9ZKE9	W9YCI5	Uncharacterized protein.	Hexaprenyl pyrophosphate synthase, mitochondrial; Belongs to the FPP/GGPP synthase family.	0.769
A1O1_00097	A1O1_07938	W9ZKE9	W9XNV2	Uncharacterized protein.	Undecaprenyl diphosphate synthase.	0.771
A1O1_00273	A1O1_00512	W9ZKW1	W9Z1F8	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	Peptidase_M48 domain-containing protein.	0.824
A1O1_00273	A1O1_01278	W9ZKW1	W9YTC3	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	Uncharacterized protein.	0.512
A1O1_00273	A1O1_01328	W9ZKW1	W9YTH0	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.896
A1O1_00273	A1O1_01949	W9ZKW1	W9YKW9	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	Prenyl protein peptidase.	0.900
A1O1_00273	A1O1_03048	W9ZKW1	W9YNY5	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.512
A1O1_00273	A1O1_04580	W9ZKW1	W9YEG0	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	Abhydrolase_3 domain-containing protein.	0.755
A1O1_00512	A1O1_00273	W9Z1F8	W9ZKW1	Peptidase_M48 domain-containing protein.	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	0.824
A1O1_00512	A1O1_01278	W9Z1F8	W9YTC3	Peptidase_M48 domain-containing protein.	Uncharacterized protein.	0.784
A1O1_00512	A1O1_01328	W9Z1F8	W9YTH0	Peptidase_M48 domain-containing protein.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.481
A1O1_00512	A1O1_01949	W9Z1F8	W9YKW9	Peptidase_M48 domain-containing protein.	Prenyl protein peptidase.	0.885
A1O1_00512	A1O1_03048	W9Z1F8	W9YNY5	Peptidase_M48 domain-containing protein.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.806
A1O1_00726	A1O1_03221	W9ZM85	W9YQJ9	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Mitochondrial import receptor subunit tom-70.	0.436
A1O1_01278	A1O1_00273	W9YTC3	W9ZKW1	Uncharacterized protein.	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	0.512
A1O1_01278	A1O1_00512	W9YTC3	W9Z1F8	Uncharacterized protein.	Peptidase_M48 domain-containing protein.	0.784
A1O1_01278	A1O1_01328	W9YTC3	W9YTH0	Uncharacterized protein.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.882
A1O1_01278	A1O1_01350	W9YTC3	W9ZNZ4	Uncharacterized protein.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.432