STRINGSTRING
A1O3_03320 A1O3_03320 A1O3_09384 A1O3_09384 A1O3_08254 A1O3_08254 FEN1 FEN1 A1O3_07717 A1O3_07717 A1O3_03294 A1O3_03294 A1O3_03671 A1O3_03671 SLX4 SLX4 A1O3_05351 A1O3_05351 A1O3_05726 A1O3_05726 A1O3_01891 A1O3_01891 A1O3_08710 A1O3_08710 A1O3_01519 A1O3_01519 SLX1 SLX1 A1O3_06786 A1O3_06786 A1O3_05157 A1O3_05157
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O3_03320Ydc2-catalyt domain-containing protein. (335 aa)
A1O3_09384Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (974 aa)
A1O3_08254Uncharacterized protein. (350 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (413 aa)
A1O3_07717DNA excision repair protein ERCC-5. (1309 aa)
A1O3_03294DNA excision repair protein ERCC-4. (943 aa)
A1O3_03671XPGI domain-containing protein. (794 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (919 aa)
A1O3_05351Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (758 aa)
A1O3_05726DNA replication ATP-dependent helicase Dna2. (1687 aa)
A1O3_01891Uncharacterized protein. (772 aa)
A1O3_08710Zn(2)-C6 fungal-type domain-containing protein. (707 aa)
A1O3_01519Endonuclease. (356 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (412 aa)
A1O3_06786Crossover junction endonuclease MUS81. (617 aa)
A1O3_05157Uncharacterized protein. (742 aa)
Your Current Organism:
Capronia epimyces
NCBI taxonomy Id: 1182542
Other names: C. epimyces CBS 606.96, Capronia epimyces CBS 606.96
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