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A1O3_02485 A1O3_02485 A1O3_10080 A1O3_10080 A1O3_09559 A1O3_09559 MCM7 MCM7 A1O3_08268 A1O3_08268 A1O3_10168 A1O3_10168 A1O3_09823 A1O3_09823 A1O3_09985 A1O3_09985 A1O3_07286 A1O3_07286 FEN1 FEN1 A1O3_08541 A1O3_08541 A1O3_06537 A1O3_06537 A1O3_06196 A1O3_06196 A1O3_06206 A1O3_06206 A1O3_06502 A1O3_06502 A1O3_07989 A1O3_07989 A1O3_06820 A1O3_06820 A1O3_02636 A1O3_02636 A1O3_02320 A1O3_02320 A1O3_02248 A1O3_02248 A1O3_04027 A1O3_04027 A1O3_01395 A1O3_01395 A1O3_01218 A1O3_01218 A1O3_05959 A1O3_05959 A1O3_00786 A1O3_00786 A1O3_00676 A1O3_00676 A1O3_05719 A1O3_05719 A1O3_00775 A1O3_00775 A1O3_05456 A1O3_05456 A1O3_05213 A1O3_05213 A1O3_05208 A1O3_05208 A1O3_05071 A1O3_05071 A1O3_02973 A1O3_02973 A1O3_01764 A1O3_01764 A1O3_01325 A1O3_01325 A1O3_01593 A1O3_01593 A1O3_01189 A1O3_01189 A1O3_01975 A1O3_01975 A1O3_00922 A1O3_00922 A1O3_02189 A1O3_02189 A1O3_00513 A1O3_00513 A1O3_07594 A1O3_07594 A1O3_08134 A1O3_08134 A1O3_02595 A1O3_02595 A1O3_08620 A1O3_08620 A1O3_05726 A1O3_05726 A1O3_05494 A1O3_05494 A1O3_10397 A1O3_10397 A1O3_04207 A1O3_04207 A1O3_04972 A1O3_04972 A1O3_04852 A1O3_04852 A1O3_06474 A1O3_06474 A1O3_04915 A1O3_04915 A1O3_04694 A1O3_04694
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O3_02485DNA replication complex GINS protein psf3. (181 aa)
A1O3_10080DNA helicase; Belongs to the MCM family. (896 aa)
A1O3_09559Uncharacterized protein. (164 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (811 aa)
A1O3_08268E3 ubiquitin-protein ligase RBX1. (125 aa)
A1O3_10168Replication factor C subunit 5. (354 aa)
A1O3_09823UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (327 aa)
A1O3_09985GINS complex subunit 1. (240 aa)
A1O3_07286DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (246 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (413 aa)
A1O3_08541DNA polymerase delta subunit 2. (511 aa)
A1O3_06537DNA helicase; Belongs to the MCM family. (1008 aa)
A1O3_06196Vezatin domain-containing protein. (588 aa)
A1O3_06206Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (228 aa)
A1O3_06502DNA_pol_E_B domain-containing protein. (859 aa)
A1O3_07989Replication factor C subunit 4. (352 aa)
A1O3_06820Uncharacterized protein. (563 aa)
A1O3_02636Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
A1O3_02320Zds_C domain-containing protein. (935 aa)
A1O3_02248CMGC/CDK/CDC2 protein kinase; Belongs to the protein kinase superfamily. (328 aa)
A1O3_04027AAA domain-containing protein. (397 aa)
A1O3_01395DNA polymerase. (1453 aa)
A1O3_01218Uncharacterized protein. (455 aa)
A1O3_05959BZIP domain-containing protein. (252 aa)
A1O3_00786Replication factor C subunit 3/5. (408 aa)
A1O3_00676DNA helicase; Belongs to the MCM family. (726 aa)
A1O3_05719G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (478 aa)
A1O3_00775DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2242 aa)
A1O3_05456Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (768 aa)
A1O3_05213Uncharacterized protein. (132 aa)
A1O3_05208Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (701 aa)
A1O3_05071Uncharacterized protein. (237 aa)
A1O3_02973DNA primase; Belongs to the eukaryotic-type primase small subunit family. (535 aa)
A1O3_01764Uncharacterized protein. (375 aa)
A1O3_01325DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (503 aa)
A1O3_01593DNA ligase. (867 aa)
A1O3_01189CBFD_NFYB_HMF domain-containing protein. (330 aa)
A1O3_01975Ubiquitin-40S ribosomal protein S27a. (154 aa)
A1O3_00922Uncharacterized protein. (478 aa)
A1O3_02189DNA helicase; Belongs to the MCM family. (821 aa)
A1O3_00513DNA_LIGASE_A3 domain-containing protein. (1093 aa)
A1O3_07594Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (411 aa)
A1O3_08134DNA helicase; Belongs to the MCM family. (957 aa)
A1O3_02595CMGC/CDK/CDK5 protein kinase; Belongs to the protein kinase superfamily. (414 aa)
A1O3_08620Cell division control protein; Belongs to the CDC6/cdc18 family. (610 aa)
A1O3_05726DNA replication ATP-dependent helicase Dna2. (1687 aa)
A1O3_05494AAA domain-containing protein. (963 aa)
A1O3_10397Replication factor C subunit 1. (1083 aa)
A1O3_04207DNA ligase. (900 aa)
A1O3_04972CBFD_NFYB_HMF domain-containing protein. (187 aa)
A1O3_04852DNA polymerase. (1107 aa)
A1O3_06474DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (298 aa)
A1O3_04915DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (649 aa)
A1O3_04694Uncharacterized protein. (506 aa)
Your Current Organism:
Capronia epimyces
NCBI taxonomy Id: 1182542
Other names: C. epimyces CBS 606.96, Capronia epimyces CBS 606.96
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