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A1O7_09590 A1O7_09590 A1O7_09868 A1O7_09868 A1O7_08270 A1O7_08270 A1O7_09241 A1O7_09241 A1O7_07086 A1O7_07086 A1O7_07267 A1O7_07267 A1O7_09252 A1O7_09252 A1O7_08146 A1O7_08146 A1O7_08337 A1O7_08337 A1O7_05466 A1O7_05466 A1O7_05979 A1O7_05979 A1O7_05778 A1O7_05778 A1O7_09096 A1O7_09096 A1O7_08308 A1O7_08308 A1O7_08565 A1O7_08565 A1O7_03753 A1O7_03753 A1O7_04811 A1O7_04811 ADK1 ADK1 A1O7_01966 A1O7_01966 AAH1 AAH1 A1O7_06215 A1O7_06215 ADK2 ADK2 A1O7_06008 A1O7_06008 A1O7_02930 A1O7_02930 A1O7_03070 A1O7_03070 A1O7_03046 A1O7_03046 A1O7_06633 A1O7_06633 A1O7_03502 A1O7_03502 A1O7_09652 A1O7_09652 A1O7_10025 A1O7_10025 A1O7_00915 A1O7_00915 A1O7_01251 A1O7_01251 A1O7_08522 A1O7_08522 AAH1-2 AAH1-2 A1O7_03501 A1O7_03501 A1O7_07731 A1O7_07731 A1O7_01044 A1O7_01044 A1O7_01124 A1O7_01124 A1O7_01782 A1O7_01782 A1O7_03760 A1O7_03760 A1O7_04591 A1O7_04591 A1O7_04762 A1O7_04762 A1O7_02587 A1O7_02587 A1O7_03524 A1O7_03524 A1O7_03686 A1O7_03686 A1O7_00470 A1O7_00470 A1O7_01007 A1O7_01007 A1O7_01595 A1O7_01595 A1O7_01810 A1O7_01810
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O7_09590Phosphoribosylaminoimidazole-succinocarboxamide synthase. (306 aa)
A1O7_09868CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (605 aa)
A1O7_08270Uncharacterized protein. (268 aa)
A1O7_09241S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (374 aa)
A1O7_07086AMP deaminase. (1106 aa)
A1O7_072673-carboxy-cis,cis-muconate cycloisomerase. (455 aa)
A1O7_09252Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (610 aa)
A1O7_08146GMP synthase. (548 aa)
A1O7_08337Apyrase; Belongs to the GDA1/CD39 NTPase family. (745 aa)
A1O7_05466Metallophos domain-containing protein. (609 aa)
A1O7_05979Guanylate kinase. (213 aa)
A1O7_05778GRIP domain-containing protein. (587 aa)
A1O7_09096Guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (572 aa)
A1O7_08308Glutamine amidotransferase type-1 domain-containing protein. (256 aa)
A1O7_08565Uncharacterized protein. (328 aa)
A1O7_03753Uncharacterized protein. (135 aa)
A1O7_04811Phosphoribosylformylglycinamidine synthase. (1390 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (273 aa)
A1O7_01966Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (548 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (331 aa)
A1O7_062153-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (257 aa)
A1O7_06008Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (460 aa)
A1O7_02930Amidophosphoribosyltransferase. (593 aa)
A1O7_03070Uncharacterized protein; Belongs to the 5'-nucleotidase family. (640 aa)
A1O7_03046Adenosine kinase. (340 aa)
A1O7_06633Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (393 aa)
A1O7_03502Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (190 aa)
A1O7_09652Formyltetrahydrofolate deformylase. (281 aa)
A1O7_10025Ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3. (716 aa)
A1O7_00915Adenine phosphoribosyltransferase. (213 aa)
A1O7_01251Phosphoribosylglycinamide formyltransferase. (249 aa)
A1O7_08522Uncharacterized protein. (203 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (352 aa)
A1O7_03501Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (194 aa)
A1O7_077313-carboxy-cis,cis-muconate cycloisomerase. (481 aa)
A1O7_01044Uncharacterized protein. (289 aa)
A1O7_01124Uncharacterized protein. (350 aa)
A1O7_01782Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (231 aa)
A1O7_03760Formate-tetrahydrofolate ligase. (939 aa)
A1O7_04591FAD-binding PCMH-type domain-containing protein. (1178 aa)
A1O7_04762Uncharacterized protein. (304 aa)
A1O7_02587A_deaminase domain-containing protein. (612 aa)
A1O7_03524ATP-grasp domain-containing protein. (797 aa)
A1O7_03686Uncharacterized protein. (603 aa)
A1O7_00470Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
A1O7_01007Uncharacterized protein. (737 aa)
A1O7_01595Bifunctional purine biosynthesis protein ADE17. (619 aa)
A1O7_018103-carboxy-cis,cis-muconate cycloisomerase. (456 aa)
Your Current Organism:
Cladophialophora yegresii
NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405
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