STRINGSTRING
A1O7_09868 A1O7_09868 A1O7_08270 A1O7_08270 A1O7_09241 A1O7_09241 A1O7_07086 A1O7_07086 A1O7_08146 A1O7_08146 A1O7_08337 A1O7_08337 A1O7_05979 A1O7_05979 A1O7_05778 A1O7_05778 A1O7_09096 A1O7_09096 ADK1 ADK1 A1O7_01966 A1O7_01966 AAH1 AAH1 ADK2 ADK2 A1O7_03070 A1O7_03070 A1O7_03046 A1O7_03046 A1O7_06633 A1O7_06633 A1O7_03502 A1O7_03502 A1O7_10025 A1O7_10025 A1O7_00915 A1O7_00915 A1O7_08522 A1O7_08522 AAH1-2 AAH1-2 A1O7_03501 A1O7_03501 A1O7_01782 A1O7_01782 A1O7_04591 A1O7_04591 A1O7_04762 A1O7_04762 A1O7_02587 A1O7_02587 A1O7_03686 A1O7_03686
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O7_09868CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (605 aa)
A1O7_08270Uncharacterized protein. (268 aa)
A1O7_09241S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (374 aa)
A1O7_07086AMP deaminase. (1106 aa)
A1O7_08146GMP synthase. (548 aa)
A1O7_08337Apyrase; Belongs to the GDA1/CD39 NTPase family. (745 aa)
A1O7_05979Guanylate kinase. (213 aa)
A1O7_05778GRIP domain-containing protein. (587 aa)
A1O7_09096Guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (572 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (273 aa)
A1O7_01966Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (548 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (331 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (257 aa)
A1O7_03070Uncharacterized protein; Belongs to the 5'-nucleotidase family. (640 aa)
A1O7_03046Adenosine kinase. (340 aa)
A1O7_06633Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (393 aa)
A1O7_03502Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (190 aa)
A1O7_10025Ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3. (716 aa)
A1O7_00915Adenine phosphoribosyltransferase. (213 aa)
A1O7_08522Uncharacterized protein. (203 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (352 aa)
A1O7_03501Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (194 aa)
A1O7_01782Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (231 aa)
A1O7_04591FAD-binding PCMH-type domain-containing protein. (1178 aa)
A1O7_04762Uncharacterized protein. (304 aa)
A1O7_02587A_deaminase domain-containing protein. (612 aa)
A1O7_03686Uncharacterized protein. (603 aa)
Your Current Organism:
Cladophialophora yegresii
NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405
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