STRINGSTRING
A1O7_06519 A1O7_06519 PAN2 PAN2 A1O7_09636 A1O7_09636 A1O7_08230 A1O7_08230 A1O7_08285 A1O7_08285 A1O7_08451 A1O7_08451 A1O7_08491 A1O7_08491 A1O7_08552 A1O7_08552 A1O7_08853 A1O7_08853 A1O7_08984 A1O7_08984 A1O7_08994 A1O7_08994 FEN1 FEN1 A1O7_07056 A1O7_07056 A1O7_07116 A1O7_07116 A1O7_07386 A1O7_07386 A1O7_07417 A1O7_07417 A1O7_07639 A1O7_07639 A1O7_10166 A1O7_10166 A1O7_09323 A1O7_09323 A1O7_07745 A1O7_07745 A1O7_07966 A1O7_07966 A1O7_05405 A1O7_05405 A1O7_09730 A1O7_09730 A1O7_05331 A1O7_05331 A1O7_05381 A1O7_05381 A1O7_08397 A1O7_08397 A1O7_09982 A1O7_09982 A1O7_08569 A1O7_08569 A1O7_06105 A1O7_06105 A1O7_08926 A1O7_08926 A1O7_06267 A1O7_06267 A1O7_06399 A1O7_06399 A1O7_08772 A1O7_08772 A1O7_08852 A1O7_08852 A1O7_09072 A1O7_09072 A1O7_07474 A1O7_07474 A1O7_07105 A1O7_07105 A1O7_04601 A1O7_04601 A1O7_07395 A1O7_07395 A1O7_04656 A1O7_04656 USB1 USB1 A1O7_07578 A1O7_07578 A1O7_07613 A1O7_07613 A1O7_05250 A1O7_05250 A1O7_05241 A1O7_05241 A1O7_05770 A1O7_05770 A1O7_02001 A1O7_02001 A1O7_06067 A1O7_06067 A1O7_02227 A1O7_02227 A1O7_02312 A1O7_02312 A1O7_06607 A1O7_06607 A1O7_02852 A1O7_02852 A1O7_02926 A1O7_02926 A1O7_03360 A1O7_03360 A1O7_03471 A1O7_03471 A1O7_04098 A1O7_04098 A1O7_03674 A1O7_03674 A1O7_03867 A1O7_03867 A1O7_04477 A1O7_04477 A1O7_09321 A1O7_09321 A1O7_04658 A1O7_04658 A1O7_00058 A1O7_00058 A1O7_09773 A1O7_09773 SLX1 SLX1 A1O7_05258 A1O7_05258 A1O7_00684 A1O7_00684 SLX4 SLX4 A1O7_08482 A1O7_08482 A1O7_01297 A1O7_01297 A1O7_01989 A1O7_01989 A1O7_08588 A1O7_08588 A1O7_08618 A1O7_08618 A1O7_01533 A1O7_01533 A1O7_02236 A1O7_02236 A1O7_03255 A1O7_03255 A1O7_02795 A1O7_02795 A1O7_03004 A1O7_03004 A1O7_07228 A1O7_07228 A1O7_03470 A1O7_03470 A1O7_00160 A1O7_00160 A1O7_00230 A1O7_00230 A1O7_07963 A1O7_07963 A1O7_05664 A1O7_05664 A1O7_00762 A1O7_00762 A1O7_01158 A1O7_01158 A1O7_01450 A1O7_01450 A1O7_01455 A1O7_01455 A1O7_01139 A1O7_01139 A1O7_06209 A1O7_06209 A1O7_06244 A1O7_06244 A1O7_06344 A1O7_06344 A1O7_01747 A1O7_01747 A1O7_04396 A1O7_04396 A1O7_05247 A1O7_05247 A1O7_02058 A1O7_02058 A1O7_03418 A1O7_03418 A1O7_03666 A1O7_03666 A1O7_00239 A1O7_00239
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O7_06519Uncharacterized protein. (283 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1183 aa)
A1O7_09636Endo/exonuclease/phosphatase domain-containing protein. (735 aa)
A1O7_08230Uncharacterized protein. (1551 aa)
A1O7_08285DBR1 domain-containing protein. (826 aa)
A1O7_08451Uncharacterized protein. (215 aa)
A1O7_08491Uncharacterized protein. (776 aa)
A1O7_08552Exonuclease domain-containing protein. (311 aa)
A1O7_08853Uncharacterized protein. (269 aa)
A1O7_08984zf-C2HE domain-containing protein. (273 aa)
A1O7_08994DNA polymerase gamma 1. (1154 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)
A1O7_07056TNase-like domain-containing protein. (289 aa)
A1O7_07116Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (938 aa)
A1O7_07386Ribonuclease P/MRP protein subunit RPP1. (336 aa)
A1O7_07417Exonuclease domain-containing protein. (700 aa)
A1O7_07639XPGI domain-containing protein. (815 aa)
A1O7_10166Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1434 aa)
A1O7_09323Uncharacterized protein. (348 aa)
A1O7_077455'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1055 aa)
A1O7_07966RNase III domain-containing protein. (339 aa)
A1O7_05405DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2237 aa)
A1O7_09730Endonuclease. (363 aa)
A1O7_05331Uncharacterized protein. (644 aa)
A1O7_0538118S rRNA biogenesis protein RCL1. (407 aa)
A1O7_08397ERCC4 domain-containing protein. (656 aa)
A1O7_09982RNase III domain-containing protein. (394 aa)
A1O7_08569Uncharacterized protein. (332 aa)
A1O7_06105Uncharacterized protein. (782 aa)
A1O7_08926Uncharacterized protein. (335 aa)
A1O7_06267DNA replication ATP-dependent helicase Dna2. (1693 aa)
A1O7_06399Uncharacterized protein. (231 aa)
A1O7_08772tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (316 aa)
A1O7_08852Uncharacterized protein. (352 aa)
A1O7_09072DNA polymerase. (1107 aa)
A1O7_07474Endo/exonuclease/phosphatase domain-containing protein. (335 aa)
A1O7_07105DRMBL domain-containing protein. (922 aa)
A1O7_046015'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1411 aa)
A1O7_07395Endo/exonuclease/phosphatase domain-containing protein. (747 aa)
A1O7_0465620S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (437 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (314 aa)
A1O7_07578Exonuclease domain-containing protein. (255 aa)
A1O7_07613Uncharacterized protein. (639 aa)
A1O7_05250RNase H domain-containing protein. (510 aa)
A1O7_05241SAE2 domain-containing protein. (403 aa)
A1O7_05770Uncharacterized protein. (302 aa)
A1O7_02001RNB domain-containing protein. (1090 aa)
A1O7_06067RNB domain-containing protein. (1353 aa)
A1O7_02227Endoribonuclease ysh1. (854 aa)
A1O7_02312Uncharacterized protein. (366 aa)
A1O7_06607DNA excision repair protein ERCC-1. (379 aa)
A1O7_02852Uncharacterized protein. (1052 aa)
A1O7_02926RAI1 domain-containing protein. (392 aa)
A1O7_03360Uncharacterized protein. (484 aa)
A1O7_03471Uncharacterized protein. (160 aa)
A1O7_04098Lactamase_B domain-containing protein. (695 aa)
A1O7_03674DNA excision repair protein ERCC-4. (944 aa)
A1O7_03867HRDC domain-containing protein. (824 aa)
A1O7_04477Exonuclease 1. (762 aa)
A1O7_09321Methionyl aminopeptidase. (453 aa)
A1O7_04658tRNA-intron endonuclease, archaea type. (553 aa)
A1O7_00058Uncharacterized protein. (75 aa)
A1O7_09773Exonuclease domain-containing protein. (627 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (419 aa)
A1O7_05258Piwi domain-containing protein. (1010 aa)
A1O7_00684Uncharacterized protein. (351 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (884 aa)
A1O7_08482Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (782 aa)
A1O7_01297Uncharacterized protein. (270 aa)
A1O7_01989Uncharacterized protein. (636 aa)
A1O7_08588tRNA_int_end_N2 domain-containing protein. (514 aa)
A1O7_08618Uncharacterized protein. (717 aa)
A1O7_01533DNA excision repair protein ERCC-5. (1366 aa)
A1O7_02236Uncharacterized protein. (1049 aa)
A1O7_03255Uncharacterized protein. (880 aa)
A1O7_02795Uncharacterized protein. (1100 aa)
A1O7_03004Uncharacterized protein. (159 aa)
A1O7_07228ERCC4 domain-containing protein. (640 aa)
A1O7_03470Uncharacterized protein; Belongs to the argonaute family. (928 aa)
A1O7_00160Uncharacterized protein. (524 aa)
A1O7_00230Uncharacterized protein. (332 aa)
A1O7_07963Uncharacterized protein. (434 aa)
A1O7_05664Exonuclease domain-containing protein. (463 aa)
A1O7_00762Uncharacterized protein. (796 aa)
A1O7_01158Uncharacterized protein. (225 aa)
A1O7_01450Zn(2)-C6 fungal-type domain-containing protein. (702 aa)
A1O7_01455rRNA-processing protein FCF1. (185 aa)
A1O7_01139Uncharacterized protein; Belongs to the RNR ribonuclease family. (1006 aa)
A1O7_06209XPG_I_2 domain-containing protein. (658 aa)
A1O7_06244Uncharacterized protein. (281 aa)
A1O7_06344RNase III domain-containing protein. (165 aa)
A1O7_01747IRE protein kinase. (1192 aa)
A1O7_04396Uncharacterized protein; Belongs to the RNase T2 family. (481 aa)
A1O7_05247Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (339 aa)
A1O7_02058Piwi domain-containing protein. (1246 aa)
A1O7_03418TatD DNase family protein. (315 aa)
A1O7_03666Ydc2-catalyt domain-containing protein. (322 aa)
A1O7_00239Uncharacterized protein; Belongs to the RNase T2 family. (323 aa)
Your Current Organism:
Cladophialophora yegresii
NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405
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