116 items (Cladophialophora yegresii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A1O7_02929	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (625 aa)
	A1O7_01338	Uncharacterized protein. (397 aa)
	A1O7_00825	DUF2428 domain-containing protein. (1573 aa)
	A1O7_00765	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA. (690 aa)
	A1O7_00089	A to I editase domain-containing protein. (437 aa)
	A1O7_03696	Fe2OG dioxygenase domain-containing protein. (353 aa)
	A1O7_02927	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (474 aa)
	A1O7_02163	TRUD domain-containing protein. (810 aa)
	A1O7_01632	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (353 aa)
	A1O7_06244	Uncharacterized protein. (281 aa)
	A1O7_01195	Rhodanese domain-containing protein. (742 aa)
	A1O7_06148	CMP/dCMP-type deaminase domain-containing protein. (219 aa)
	A1O7_01545	Uncharacterized protein. (975 aa)
	A1O7_06138	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1358 aa)
	TRM8	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (302 aa)
	A1O7_00907	Uncharacterized protein. (303 aa)
	A1O7_05472	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (772 aa)
	A1O7_00056	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
	A1O7_00310	Uncharacterized protein. (288 aa)
	A1O7_03390	TYW3 domain-containing protein. (453 aa)
	URM1	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (105 aa)
	A1O7_03004	Uncharacterized protein. (159 aa)
	A1O7_02471	Small nuclear ribonucleoprotein. (133 aa)
	A1O7_02795	Uncharacterized protein. (1100 aa)
	A1O7_01729	Small nuclear ribonucleoprotein. (95 aa)
	A1O7_02830	Uncharacterized protein. (380 aa)
	A1O7_02236	Uncharacterized protein. (1049 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	A1O7_02578	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (751 aa)
	A1O7_08588	tRNA_int_end_N2 domain-containing protein. (514 aa)
	NBP35	Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (346 aa)
	A1O7_01362	Uncharacterized protein. (146 aa)
	A1O7_01292	Uncharacterized protein. (325 aa)
	A1O7_01272	Uncharacterized protein. (199 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (150 aa)
	A1O7_02305	Uncharacterized protein. (247 aa)
	A1O7_08301	ATP_bind_3 domain-containing protein. (479 aa)
	NCS6	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (411 aa)
	KAE1	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (375 aa)
	A1O7_02013	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (200 aa)
	A1O7_05234	Methyltransf_11 domain-containing protein. (252 aa)
	A1O7_00959	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (117 aa)
	A1O7_10030	Uncharacterized protein. (516 aa)
	A1O7_04699	Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (474 aa)
	A1O7_00288	Uncharacterized protein. (1147 aa)
	A1O7_00198	tRNA pseudouridine38-40 synthase. (644 aa)
	A1O7_04673	Uncharacterized protein. (665 aa)
	A1O7_04658	tRNA-intron endonuclease, archaea type. (553 aa)
	A1O7_09351	BUD32 protein kinase. (346 aa)
	A1O7_03665	Uncharacterized protein. (246 aa)
	A1O7_03397	tRNA (Adenine57-N1/adenine58-N1)-methyltransferase. (517 aa)
	A1O7_03476	Uncharacterized protein. (624 aa)
	A1O7_03248	Uncharacterized protein. (199 aa)
	A1O7_03334	Initiator tRNA phosphoribosyl transferase. (467 aa)
	A1O7_03141	Uncharacterized protein. (884 aa)
	A1O7_03071	Uncharacterized protein. (372 aa)
	A1O7_06276	UPF0020 domain-containing protein. (514 aa)
	A1O7_09812	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (308 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (145 aa)
	A1O7_10138	Cysteine desulfurase. (511 aa)
	A1O7_08037	Uncharacterized protein. (570 aa)
	A1O7_08018	tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (310 aa)
	A1O7_08626	TruB_N domain-containing protein. (422 aa)
	A1O7_08451	Uncharacterized protein. (215 aa)
	NCS2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (359 aa)
	A1O7_08773	Ribonuclease P protein subunit. (252 aa)
	A1O7_08934	JmjC domain-containing protein. (1142 aa)
	A1O7_06976	tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (453 aa)
	A1O7_06996	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1030 aa)
	A1O7_07021	tRNA-dihydrouridine synthase 2. (424 aa)
	A1O7_06857	DPH-type MB domain-containing protein. (132 aa)
	A1O7_06927	Uncharacterized protein. (503 aa)
	A1O7_07166	DUF3453 domain-containing protein. (768 aa)
	A1O7_09517	Uncharacterized protein. (546 aa)
	TRM5	tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (467 aa)
	A1O7_09648	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (424 aa)
	A1O7_07386	Ribonuclease P/MRP protein subunit RPP1. (336 aa)
	ALA1	Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (962 aa)
	A1O7_07417	Exonuclease domain-containing protein. (700 aa)
	TRM82	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (565 aa)
	A1O7_07664	PseudoU_synth_1 domain-containing protein. (693 aa)
	A1O7_10021	Uncharacterized protein. (505 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1137 aa)
	A1O7_09659	YrdC-like domain-containing protein. (547 aa)
	A1O7_08232	SAM_MT_TRM5_TYW2 domain-containing protein. (506 aa)
	A1O7_05450	Uncharacterized protein. (664 aa)
	A1O7_08574	Flavodoxin-like domain-containing protein. (792 aa)
	A1O7_05877	Uncharacterized protein. (269 aa)
	A1O7_06004	Alanyl-tRNA synthetase. (276 aa)
	A1O7_08771	Elongator complex protein 4. (386 aa)
	A1O7_08086	ThiF domain-containing protein. (517 aa)
	A1O7_09081	Protein phosphatase. (483 aa)
	A1O7_06273	tRNA ligase. (822 aa)
	A1O7_06399	Uncharacterized protein. (231 aa)
	A1O7_08585	Queuosine salvage protein; Involved in salvaging queuosine. (373 aa)
	A1O7_02476	Uncharacterized protein. (272 aa)
	A1O7_06494	Uncharacterized protein. (331 aa)
	A1O7_06684	Uncharacterized protein. (421 aa)
	A1O7_08671	Pseudouridylate synthase. (563 aa)
	A1O7_06584	Uncharacterized protein. (266 aa)
	A1O7_08772	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (316 aa)
	A1O7_07119	Uncharacterized protein. (132 aa)
	A1O7_08952	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (701 aa)
	A1O7_04090	Lysyl-tRNA synthetase, class II. (399 aa)
	A1O7_04227	SAM-dependent MTase TRM10-type domain-containing protein. (573 aa)
	A1O7_04400	THUMP domain-containing protein. (319 aa)
	A1O7_06551	Formyl_trans_N domain-containing protein. (427 aa)
	A1O7_04730	Uncharacterized protein. (259 aa)
	A1O7_07848	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (889 aa)
	A1O7_04805	HD_domain domain-containing protein. (234 aa)
	CFD1	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (322 aa)
	AIM41	Altered inheritance of mitochondria protein 41. (203 aa)
	A1O7_05488	Uncharacterized protein. (442 aa)
	A1O7_05695	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (403 aa)
	A1O7_02364	tRNA-dihydrouridine synthase 1. (533 aa)
	A1O7_06421	Sen15 domain-containing protein. (259 aa)

Your Current Organism:

Cladophialophora yegresii

NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O7_00056	A1O7_00198	W9WGL0	W9W7D5	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	tRNA pseudouridine38-40 synthase.	0.513
A1O7_00056	A1O7_00907	W9WGL0	W9WHW2	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.961
A1O7_00056	A1O7_01195	W9WGL0	W9WJU0	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Rhodanese domain-containing protein.	0.698
A1O7_00056	A1O7_01272	W9WGL0	W9WAH5	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.843
A1O7_00056	A1O7_01338	W9WGL0	W9X3D6	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.823
A1O7_00056	A1O7_01362	W9WGL0	W9WAR1	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.482
A1O7_00056	A1O7_01545	W9WGL0	W9WJP2	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.483
A1O7_00056	A1O7_02163	W9WGL0	W9WTS8	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	TRUD domain-containing protein.	0.422
A1O7_00056	A1O7_02236	W9WGL0	W9WB78	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.456
A1O7_00056	A1O7_02364	W9WGL0	W9W1W6	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	tRNA-dihydrouridine synthase 1.	0.458
A1O7_00056	A1O7_02830	W9WGL0	W9WBN9	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.895
A1O7_00056	A1O7_03141	W9WGL0	W9W419	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.989
A1O7_00056	A1O7_03665	W9WGL0	W9W5H9	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.579
A1O7_00056	A1O7_05234	W9WGL0	W9W972	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Methyltransf_11 domain-containing protein.	0.504
A1O7_00056	A1O7_05450	W9WGL0	W9VQM8	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.843
A1O7_00056	A1O7_05472	W9WGL0	W9WHS0	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.	0.551
A1O7_00056	A1O7_05488	W9WGL0	W9VZC7	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.492
A1O7_00056	A1O7_06138	W9WGL0	W9WJN5	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	0.997
A1O7_00056	A1O7_06276	W9WGL0	W9W2V3	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	UPF0020 domain-containing protein.	0.460
A1O7_00056	A1O7_06857	W9WGL0	W9VLX6	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	DPH-type MB domain-containing protein.	0.757