(54 nodes) Extrinsic component of membrane network (Cladophialophora yegresii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A1O7_00938	zf-Mss51 domain-containing protein. (550 aa)
	A1O7_06082	Uncharacterized protein. (325 aa)
	A1O7_01866	ULK/ULK protein kinase. (989 aa)
	A1O7_10152	Guanine nucleotide-binding protein subunit alpha. (353 aa)
	A1O7_06317	Guanine nucleotide-binding protein subunit alpha, other. (343 aa)
	A1O7_06423	Uncharacterized protein. (321 aa)
	A1O7_06834	Uncharacterized protein. (809 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (523 aa)
	A1O7_03954	Uncharacterized protein. (355 aa)
	A1O7_03964	Uncharacterized protein. (754 aa)
	A1O7_04178	Uncharacterized protein. (508 aa)
	A1O7_02284	Uncharacterized protein. (77 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (240 aa)
	A1O7_07374	Uncharacterized protein. (269 aa)
	A1O7_04459	PRELI/MSF1 domain-containing protein. (241 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (346 aa)
	A1O7_07908	Rav1p_C domain-containing protein. (1318 aa)
	A1O7_02844	FAD-binding FR-type domain-containing protein. (407 aa)
	A1O7_03357	Uncharacterized protein. (400 aa)
	A1O7_01268	1-phosphatidylinositol-3-phosphate 5-kinase. (2467 aa)
	A1O7_05398	SAP30_Sin3_bdg domain-containing protein. (307 aa)
	A1O7_05364	26S proteasome regulatory subunit N3. (864 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (300 aa)
	A1O7_09635	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3194 aa)
	A1O7_08058	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (168 aa)
	A1O7_08093	Phosphatidylinositol 3-kinase VPS34. (936 aa)
	A1O7_08622	Guanine nucleotide-binding protein subunit beta. (353 aa)
	A1O7_09113	Dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (913 aa)
	A1O7_07624	ATG11 domain-containing protein. (1426 aa)
	A1O7_07775	OBG-type G domain-containing protein. (623 aa)
	A1O7_07875	Uncharacterized protein. (527 aa)
	A1O7_06372	Uncharacterized protein. (750 aa)
	A1O7_06577	G protein beta subunit-like protein. (412 aa)
	A1O7_04267	DNA repair and recombination protein RAD54 and RAD54-like protein. (980 aa)
	A1O7_00048	Uncharacterized protein. (336 aa)
	A1O7_00337	Guanine nucleotide-binding protein alpha-3 subunit. (357 aa)
	A1O7_09975	Uncharacterized protein. (377 aa)
	A1O7_05104	Uncharacterized protein. (386 aa)
	A1O7_05214	Uncharacterized protein. (290 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (302 aa)
	A1O7_08236	SAC domain-containing protein. (1076 aa)
	A1O7_01051	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (191 aa)
	A1O7_07895	Uncharacterized protein. (105 aa)
	A1O7_08025	Uncharacterized protein. (358 aa)
	A1O7_08341	VPS15 protein kinase. (1631 aa)
	A1O7_01648	UBX domain-containing protein. (502 aa)
	A1O7_02604	Methyltranfer_dom domain-containing protein. (282 aa)
	A1O7_03389	Uncharacterized protein. (253 aa)
	A1O7_03490	GTP-binding protein rhb1. (188 aa)
	A1O7_05395	Molecular chaperone DnaJ. (548 aa)
	A1O7_03550	Erf4 domain-containing protein. (559 aa)
	A1O7_07526	Guanine nucleotide-binding protein subunit gamma. (93 aa)
	A1O7_00886	AarF domain-containing kinase. (784 aa)
	A1O7_05869	Uncharacterized protein. (592 aa)

Your Current Organism:

Cladophialophora yegresii

NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O7_00048	A1O7_07875	W9W6W1	W9VP77	Uncharacterized protein.	Uncharacterized protein.	0.447
A1O7_00337	A1O7_03490	W9W7C1	W9WDH0	Guanine nucleotide-binding protein alpha-3 subunit.	GTP-binding protein rhb1.	0.541
A1O7_00337	A1O7_07526	W9W7C1	W9WF82	Guanine nucleotide-binding protein alpha-3 subunit.	Guanine nucleotide-binding protein subunit gamma.	0.751
A1O7_00337	A1O7_08025	W9W7C1	W9VQ12	Guanine nucleotide-binding protein alpha-3 subunit.	Uncharacterized protein.	0.711
A1O7_00337	A1O7_08622	W9W7C1	W9VJK5	Guanine nucleotide-binding protein alpha-3 subunit.	Guanine nucleotide-binding protein subunit beta.	0.948
A1O7_00337	A1O7_10152	W9W7C1	W9VRM0	Guanine nucleotide-binding protein alpha-3 subunit.	Guanine nucleotide-binding protein subunit alpha.	0.695
A1O7_00886	A1O7_02604	W9WHU2	W9WC80	AarF domain-containing kinase.	Methyltranfer_dom domain-containing protein.	0.724
A1O7_00886	A1O7_03389	W9WHU2	W9WD69	AarF domain-containing kinase.	Uncharacterized protein.	0.724
A1O7_00886	A1O7_05364	W9WHU2	W9W0B3	AarF domain-containing kinase.	26S proteasome regulatory subunit N3.	0.524
A1O7_00886	A1O7_07374	W9WHU2	W9VWG3	AarF domain-containing kinase.	Uncharacterized protein.	0.724
A1O7_00886	COQ3	W9WHU2	W9VXA6	AarF domain-containing kinase.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.877
A1O7_00886	COQ4	W9WHU2	W9W2J4	AarF domain-containing kinase.	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	0.652
A1O7_00886	COQ5	W9WHU2	W9VF72	AarF domain-containing kinase.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.846
A1O7_00886	COQ6	W9WHU2	W9VU86	AarF domain-containing kinase.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.696
A1O7_00886	COQ7	W9WHU2	W9VVZ9	AarF domain-containing kinase.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.692
A1O7_01051	A1O7_03490	W9W9T3	W9WDH0	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	GTP-binding protein rhb1.	0.407
A1O7_01268	A1O7_04267	W9X369	W9W541	1-phosphatidylinositol-3-phosphate 5-kinase.	DNA repair and recombination protein RAD54 and RAD54-like protein.	0.981
A1O7_01268	A1O7_06834	W9X369	W9VTY9	1-phosphatidylinositol-3-phosphate 5-kinase.	Uncharacterized protein.	0.661
A1O7_01268	A1O7_08093	W9X369	W9VI43	1-phosphatidylinositol-3-phosphate 5-kinase.	Phosphatidylinositol 3-kinase VPS34.	0.913
A1O7_01268	A1O7_08236	W9X369	W9W9S5	1-phosphatidylinositol-3-phosphate 5-kinase.	SAC domain-containing protein.	0.996