(66 nodes) Dicarboxylic acid metabolic process network (Cladophialophora yegresii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A1O7_05985	Mur_ligase_M domain-containing protein. (517 aa)
	A1O7_01810	3-carboxy-cis,cis-muconate cycloisomerase. (456 aa)
	A1O7_01509	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (515 aa)
	A1O7_01353	Ornithine aminotransferase. (483 aa)
	A1O7_01072	Aspartate-semialdehyde dehydrogenase. (366 aa)
	A1O7_00470	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
	A1O7_03479	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (499 aa)
	A1O7_03157	Malate dehydrogenase. (332 aa)
	A1O7_05117	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (314 aa)
	A1O7_04456	Uncharacterized protein. (310 aa)
	A1O7_01812	Succinate-semialdehyde dehydrogenase. (508 aa)
	A1O7_06706	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (457 aa)
	A1O7_01896	Succinate-semialdehyde dehydrogenase. (497 aa)
	A1O7_06445	Chorismate synthase. (426 aa)
	A1O7_01269	Kynurenine 3-monooxygenase. (451 aa)
	A1O7_00817	Malate dehydrogenase. (341 aa)
	A1O7_00687	Succinate-semialdehyde dehydrogenase. (512 aa)
	A1O7_05528	Dihydropteroate synthase. (470 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (189 aa)
	A1O7_00256	Uncharacterized protein. (864 aa)
	A1O7_07731	3-carboxy-cis,cis-muconate cycloisomerase. (481 aa)
	A1O7_07606	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1617 aa)
	A1O7_07413	Uncharacterized protein. (356 aa)
	A1O7_03168	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (505 aa)
	A1O7_01793	Uncharacterized protein. (196 aa)
	A1O7_01708	Fe-ADH domain-containing protein. (360 aa)
	A1O7_01428	Uncharacterized protein. (315 aa)
	A1O7_02548	Nitrilase. (297 aa)
	A1O7_02300	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family. (494 aa)
	A1O7_01125	Malic enzyme. (586 aa)
	A1O7_05014	CN hydrolase domain-containing protein. (372 aa)
	A1O7_00419	Uncharacterized protein. (151 aa)
	A1O7_09910	Aspartate aminotransferase. (430 aa)
	A1O7_00257	Shikimate_dh_N domain-containing protein. (307 aa)
	A1O7_04278	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (459 aa)
	A1O7_04457	Uncharacterized protein. (336 aa)
	A1O7_03817	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (527 aa)
	A1O7_03377	Fumarate hydratase, mitochondrial. (468 aa)
	A1O7_03217	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (518 aa)
	A1O7_02946	Aminodeoxychorismate synthase. (801 aa)
	A1O7_03020	M20_dimer domain-containing protein. (426 aa)
	A1O7_06286	Uncharacterized protein. (139 aa)
	A1O7_02616	Hippurate hydrolase. (435 aa)
	A1O7_02510	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (393 aa)
	A1O7_06215	3-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
	A1O7_05195	Uncharacterized protein. (409 aa)
	A1O7_07638	FolB domain-containing protein. (259 aa)
	A1O7_04691	3-dehydroquinate synthase. (503 aa)
	A1O7_04765	Glutamate synthase [NADPH]. (2152 aa)
	A1O7_04615	GTP cyclohydrolase I. (366 aa)
	A1O7_07229	Oxalate decarboxylase. (520 aa)
	A1O7_06979	Malic enzyme. (597 aa)
	A1O7_06338	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (550 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (518 aa)
	A1O7_09121	Oxalate decarboxylase. (442 aa)
	A1O7_05853	Uncharacterized protein. (95 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (488 aa)
	A1O7_08382	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (486 aa)
	A1O7_05592	Aspartate aminotransferase. (422 aa)
	A1O7_09257	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1069 aa)
	A1O7_07412	Uncharacterized protein. (197 aa)
	A1O7_07267	3-carboxy-cis,cis-muconate cycloisomerase. (455 aa)
	A1O7_07216	Uncharacterized protein. (363 aa)
	A1O7_09547	2-oxoglutarate dehydrogenase, mitochondrial. (1005 aa)
	A1O7_08390	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (586 aa)
	A1O7_08144	Chorismate mutase. (275 aa)

Your Current Organism:

Cladophialophora yegresii

NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O7_00256	A1O7_01072	W9WH53	W9X2M4	Uncharacterized protein.	Aspartate-semialdehyde dehydrogenase.	0.467
A1O7_00256	A1O7_01509	W9WH53	W9X3V0	Uncharacterized protein.	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family.	0.469
A1O7_00256	A1O7_01793	W9WH53	W9WBG9	Uncharacterized protein.	Uncharacterized protein.	0.469
A1O7_00256	A1O7_02946	W9WH53	W9W3I5	Uncharacterized protein.	Aminodeoxychorismate synthase.	0.482
A1O7_00256	A1O7_05592	W9WH53	W9VR09	Uncharacterized protein.	Aspartate aminotransferase.	0.504
A1O7_00256	A1O7_06445	W9WH53	W9WKM8	Uncharacterized protein.	Chorismate synthase.	0.771
A1O7_00256	A1O7_08144	W9WH53	W9VI84	Uncharacterized protein.	Chorismate mutase.	0.737
A1O7_00256	A1O7_09910	W9WH53	W9W7N7	Uncharacterized protein.	Aspartate aminotransferase.	0.498
A1O7_00257	A1O7_01072	W9W756	W9X2M4	Shikimate_dh_N domain-containing protein.	Aspartate-semialdehyde dehydrogenase.	0.467
A1O7_00257	A1O7_01509	W9W756	W9X3V0	Shikimate_dh_N domain-containing protein.	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family.	0.469
A1O7_00257	A1O7_01793	W9W756	W9WBG9	Shikimate_dh_N domain-containing protein.	Uncharacterized protein.	0.469
A1O7_00257	A1O7_02946	W9W756	W9W3I5	Shikimate_dh_N domain-containing protein.	Aminodeoxychorismate synthase.	0.482
A1O7_00257	A1O7_04456	W9W756	W9WPH4	Shikimate_dh_N domain-containing protein.	Uncharacterized protein.	0.802
A1O7_00257	A1O7_04691	W9W756	W9VXZ8	Shikimate_dh_N domain-containing protein.	3-dehydroquinate synthase.	0.793
A1O7_00257	A1O7_05592	W9W756	W9VR09	Shikimate_dh_N domain-containing protein.	Aspartate aminotransferase.	0.504
A1O7_00257	A1O7_06445	W9W756	W9WKM8	Shikimate_dh_N domain-containing protein.	Chorismate synthase.	0.809
A1O7_00257	A1O7_07606	W9W756	W9WFF7	Shikimate_dh_N domain-containing protein.	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family.	0.811
A1O7_00257	A1O7_08144	W9W756	W9VI84	Shikimate_dh_N domain-containing protein.	Chorismate mutase.	0.737
A1O7_00257	A1O7_09910	W9W756	W9W7N7	Shikimate_dh_N domain-containing protein.	Aspartate aminotransferase.	0.498
A1O7_00470	A1O7_00817	W9X0W1	W9WIN9	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Malate dehydrogenase.	0.829