STRINGSTRING
A1O7_00156 A1O7_00156 A1O7_09173 A1O7_09173 A1O7_09305 A1O7_09305 A1O7_09766 A1O7_09766 A1O7_09857 A1O7_09857 A1O7_10083 A1O7_10083 A1O7_08032 A1O7_08032 A1O7_08198 A1O7_08198 A1O7_08435 A1O7_08435 A1O7_08646 A1O7_08646 A1O7_08909 A1O7_08909 FEN1 FEN1 A1O7_07639 A1O7_07639 A1O7_09152 A1O7_09152 A1O7_10061 A1O7_10061 A1O7_07962 A1O7_07962 A1O7_09558 A1O7_09558 A1O7_05405 A1O7_05405 A1O7_09831 A1O7_09831 A1O7_05517 A1O7_05517 A1O7_05532 A1O7_05532 A1O7_08559 A1O7_08559 A1O7_05752 A1O7_05752 A1O7_08725 A1O7_08725 A1O7_08916 A1O7_08916 A1O7_06117 A1O7_06117 A1O7_06267 A1O7_06267 A1O7_06479 A1O7_06479 A1O7_07024 A1O7_07024 A1O7_08862 A1O7_08862 A1O7_09072 A1O7_09072 A1O7_04071 A1O7_04071 A1O7_04671 A1O7_04671 A1O7_07496 A1O7_07496 A1O7_07854 A1O7_07854 A1O7_02247 A1O7_02247 A1O7_05947 A1O7_05947 A1O7_02904 A1O7_02904 A1O7_03025 A1O7_03025 A1O7_03548 A1O7_03548 A1O7_04368 A1O7_04368 A1O7_00167 A1O7_00167 A1O7_09768 A1O7_09768 A1O7_00317 A1O7_00317 A1O7_00508 A1O7_00508 A1O7_04899 A1O7_04899 A1O7_00549 A1O7_00549 A1O7_00784 A1O7_00784 A1O7_08034 A1O7_08034 A1O7_08286 A1O7_08286 A1O7_08462 A1O7_08462 A1O7_01398 A1O7_01398 A1O7_08820 A1O7_08820 MCM7 MCM7 A1O7_09045 A1O7_09045 A1O7_02599 A1O7_02599 A1O7_03235 A1O7_03235 A1O7_07258 A1O7_07258 A1O7_00606 A1O7_00606 A1O7_05674 A1O7_05674 A1O7_06274 A1O7_06274 A1O7_06480 A1O7_06480 A1O7_06701 A1O7_06701 A1O7_04016 A1O7_04016 A1O7_04157 A1O7_04157 A1O7_04581 A1O7_04581 A1O7_02274 A1O7_02274 A1O7_01253 A1O7_01253 A1O7_01645 A1O7_01645
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O7_00156Zds_C domain-containing protein. (815 aa)
A1O7_09173DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (265 aa)
A1O7_09305DNA ligase. (867 aa)
A1O7_09766Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (263 aa)
A1O7_09857DNA helicase; Belongs to the MCM family. (1006 aa)
A1O7_10083Replication factor C subunit 1. (1080 aa)
A1O7_08032J domain-containing protein. (313 aa)
A1O7_08198Uncharacterized protein. (367 aa)
A1O7_08435AAA domain-containing protein. (1102 aa)
A1O7_08646Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
A1O7_08909CBFD_NFYB_HMF domain-containing protein. (182 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)
A1O7_07639XPGI domain-containing protein. (815 aa)
A1O7_09152Uncharacterized protein. (445 aa)
A1O7_10061Replication factor C subunit 5. (354 aa)
A1O7_07962Zf-primase domain-containing protein. (751 aa)
A1O7_09558DNA helicase; Belongs to the MCM family. (910 aa)
A1O7_05405DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2237 aa)
A1O7_09831DNA_pol_E_B domain-containing protein. (844 aa)
A1O7_05517DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (226 aa)
A1O7_05532Uncharacterized protein. (792 aa)
A1O7_08559Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (670 aa)
A1O7_05752DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (503 aa)
A1O7_08725Uncharacterized protein. (131 aa)
A1O7_08916Uncharacterized protein. (236 aa)
A1O7_06117GINS complex subunit 1. (227 aa)
A1O7_06267DNA replication ATP-dependent helicase Dna2. (1693 aa)
A1O7_06479BZIP domain-containing protein. (263 aa)
A1O7_07024AAA domain-containing protein. (419 aa)
A1O7_08862DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (650 aa)
A1O7_09072DNA polymerase. (1107 aa)
A1O7_04071CDC7 protein kinase. (476 aa)
A1O7_04671Replication factor C subunit 3/5. (408 aa)
A1O7_07496ORC_WH_C domain-containing protein. (694 aa)
A1O7_07854Cell division control protein 45. (848 aa)
A1O7_02247Uncharacterized protein. (455 aa)
A1O7_05947UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (326 aa)
A1O7_02904Uncharacterized protein. (652 aa)
A1O7_03025RING-box protein 1. (123 aa)
A1O7_03548Replication factor C subunit 4. (353 aa)
A1O7_04368Ubiquitin-40S ribosomal protein S27a. (154 aa)
A1O7_00167DBF4-type domain-containing protein. (639 aa)
A1O7_09768Vezatin domain-containing protein. (590 aa)
A1O7_00317DNA helicase; Belongs to the MCM family. (865 aa)
A1O7_00508CMGC/CDK/CDK5 protein kinase; Belongs to the protein kinase superfamily. (337 aa)
A1O7_04899Uncharacterized protein. (503 aa)
A1O7_00549Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
A1O7_00784CMGC/CDK/CDC2 protein kinase; Belongs to the protein kinase superfamily. (326 aa)
A1O7_08034Stn1 domain-containing protein. (347 aa)
A1O7_08286Uncharacterized protein. (434 aa)
A1O7_08462Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (772 aa)
A1O7_01398Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (411 aa)
A1O7_08820Uncharacterized protein. (521 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (818 aa)
A1O7_09045RPA_C domain-containing protein. (286 aa)
A1O7_02599CBFD_NFYB_HMF domain-containing protein. (358 aa)
A1O7_03235DNA helicase; Belongs to the MCM family. (959 aa)
A1O7_07258Uncharacterized protein. (558 aa)
A1O7_00606DNA replication complex GINS protein psf3. (181 aa)
A1O7_05674DNA polymerase. (1449 aa)
A1O7_06274G2/mitotic-specific cyclin 1/2; Belongs to the cyclin family. (483 aa)
A1O7_06480CIA30 domain-containing protein. (260 aa)
A1O7_06701Uncharacterized protein. (150 aa)
A1O7_04016Histone H2B; Belongs to the histone H2B family. (141 aa)
A1O7_04157DNA primase; Belongs to the eukaryotic-type primase small subunit family. (525 aa)
A1O7_04581DNA helicase; Belongs to the MCM family. (725 aa)
A1O7_02274DNA ligase. (896 aa)
A1O7_01253Cell division control protein; Belongs to the CDC6/cdc18 family. (595 aa)
A1O7_01645DNA polymerase delta subunit 2. (506 aa)
Your Current Organism:
Cladophialophora yegresii
NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.