16 items (Cladophialophora yegresii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Your Input:
	A1O7_02239	MoaC domain-containing protein. (363 aa)
	A1O7_10138	Cysteine desulfurase. (511 aa)
	NCS2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (359 aa)
	A1O7_09448	Sulfurtransferase. (151 aa)
	A1O7_08086	ThiF domain-containing protein. (517 aa)
	A1O7_02238	Elp3 domain-containing protein. (458 aa)
	A1O7_05841	Uncharacterized protein. (811 aa)
	A1O7_04328	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (204 aa)
	A1O7_00593	MOSC domain-containing protein. (206 aa)
	NCS6	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (411 aa)
	A1O7_01292	Uncharacterized protein. (325 aa)
	A1O7_02794	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (165 aa)
	A1O7_02453	Uncharacterized protein. (148 aa)
	URM1	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (105 aa)
	A1O7_01195	Rhodanese domain-containing protein. (742 aa)
	A1O7_00740	Uncharacterized protein. (192 aa)

Your Current Organism:

Cladophialophora yegresii

NCBI taxonomy Id: 1182544
Other names: C. yegresii CBS 114405, Cladophialophora yegresii CBS 114405

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O7_00593	A1O7_00740	W9W834	W9X1N9	MOSC domain-containing protein.	Uncharacterized protein.	0.894
A1O7_00593	A1O7_02238	W9W834	W9W1G3	MOSC domain-containing protein.	Elp3 domain-containing protein.	0.848
A1O7_00593	A1O7_02239	W9W834	W9WU21	MOSC domain-containing protein.	MoaC domain-containing protein.	0.848
A1O7_00740	A1O7_00593	W9X1N9	W9W834	Uncharacterized protein.	MOSC domain-containing protein.	0.894
A1O7_00740	A1O7_01195	W9X1N9	W9WJU0	Uncharacterized protein.	Rhodanese domain-containing protein.	0.969
A1O7_00740	A1O7_01292	W9X1N9	W9WAJ5	Uncharacterized protein.	Uncharacterized protein.	0.815
A1O7_00740	A1O7_02238	W9X1N9	W9W1G3	Uncharacterized protein.	Elp3 domain-containing protein.	0.948
A1O7_00740	A1O7_02239	W9X1N9	W9WU21	Uncharacterized protein.	MoaC domain-containing protein.	0.949
A1O7_00740	A1O7_02453	W9X1N9	W9WBS3	Uncharacterized protein.	Uncharacterized protein.	0.828
A1O7_00740	A1O7_05841	W9X1N9	W9W1N4	Uncharacterized protein.	Uncharacterized protein.	0.815
A1O7_00740	A1O7_09448	W9X1N9	W9VPP6	Uncharacterized protein.	Sulfurtransferase.	0.903
A1O7_00740	NCS6	W9X1N9	W9W9V8	Uncharacterized protein.	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.	0.406
A1O7_00740	URM1	W9X1N9	W9WDS0	Uncharacterized protein.	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]	0.773
A1O7_01195	A1O7_00740	W9WJU0	W9X1N9	Rhodanese domain-containing protein.	Uncharacterized protein.	0.969
A1O7_01195	A1O7_01292	W9WJU0	W9WAJ5	Rhodanese domain-containing protein.	Uncharacterized protein.	0.908
A1O7_01195	A1O7_02238	W9WJU0	W9W1G3	Rhodanese domain-containing protein.	Elp3 domain-containing protein.	0.764
A1O7_01195	A1O7_02239	W9WJU0	W9WU21	Rhodanese domain-containing protein.	MoaC domain-containing protein.	0.816
A1O7_01195	A1O7_02453	W9WJU0	W9WBS3	Rhodanese domain-containing protein.	Uncharacterized protein.	0.510
A1O7_01195	A1O7_04328	W9WJU0	W9W6M1	Rhodanese domain-containing protein.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.500
A1O7_01195	A1O7_05841	W9WJU0	W9W1N4	Rhodanese domain-containing protein.	Uncharacterized protein.	0.854