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A1O9_12661 A1O9_12661 A1O9_12682 A1O9_12682 COQ6 COQ6 A1O9_09357 A1O9_09357 A1O9_12774 A1O9_12774 A1O9_05449 A1O9_05449 A1O9_10106 A1O9_10106 A1O9_06147 A1O9_06147 A1O9_04388 A1O9_04388 A1O9_04796 A1O9_04796 A1O9_07981 A1O9_07981 COQ4 COQ4 A1O9_03460 A1O9_03460 A1O9_01075 A1O9_01075 COQ7 COQ7 A1O9_01382 A1O9_01382 A1O9_03798 A1O9_03798 COQ5 COQ5 COQ3 COQ3 A1O9_00603 A1O9_00603
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O9_12661NmrA domain-containing protein. (302 aa)
A1O9_12682Methyltransf_25 domain-containing protein. (250 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (529 aa)
A1O9_093572Fe-2S ferredoxin-type domain-containing protein. (215 aa)
A1O9_127744-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (328 aa)
A1O9_05449NADPH:adrenodoxin oxidoreductase, mitochondrial. (448 aa)
A1O9_10106NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial. (378 aa)
A1O9_06147AarF domain-containing kinase. (779 aa)
A1O9_04388Uncharacterized protein. (259 aa)
A1O9_04796NAD(P)-bd_dom domain-containing protein. (292 aa)
A1O9_07981Uncharacterized protein. (157 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (261 aa)
A1O9_03460Uncharacterized protein. (223 aa)
A1O9_01075Polyketide_cyc domain-containing protein. (143 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (205 aa)
A1O9_01382Methyltranfer_dom domain-containing protein. (290 aa)
A1O9_03798Hexaprenyl pyrophosphate synthase, mitochondrial; Belongs to the FPP/GGPP synthase family. (456 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (302 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (311 aa)
A1O9_00603Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (253 aa)
Your Current Organism:
Exophiala aquamarina
NCBI taxonomy Id: 1182545
Other names: E. aquamarina CBS 119918, Exophiala aquamarina CBS 119918
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