STRINGSTRING
A1O9_10330 A1O9_10330 A1O9_06108 A1O9_06108 A1O9_08265 A1O9_08265 A1O9_03476 A1O9_03476 A1O9_10796 A1O9_10796 A1O9_10059 A1O9_10059 A1O9_10046 A1O9_10046 A1O9_09817 A1O9_09817 A1O9_07842 A1O9_07842 A1O9_07364 A1O9_07364
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O9_10330Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2921 aa)
A1O9_06108Uncharacterized protein. (1606 aa)
A1O9_08265Telo_bind domain-containing protein. (652 aa)
A1O9_03476Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (298 aa)
A1O9_10796Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (484 aa)
A1O9_10059HUN domain-containing protein. (583 aa)
A1O9_10046Histone H2B; Belongs to the histone H2B family. (140 aa)
A1O9_09817Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (767 aa)
A1O9_07842DNA repair protein RAD50. (1305 aa)
A1O9_07364Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (985 aa)
Your Current Organism:
Exophiala aquamarina
NCBI taxonomy Id: 1182545
Other names: E. aquamarina CBS 119918, Exophiala aquamarina CBS 119918
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