STRINGSTRING
A1O9_04827 A1O9_04827 A1O9_04582 A1O9_04582 A1O9_08185 A1O9_08185 A1O9_08215 A1O9_08215 A1O9_04924 A1O9_04924 A1O9_04147 A1O9_04147 A1O9_04916 A1O9_04916 A1O9_08531 A1O9_08531 A1O9_04686 A1O9_04686 A1O9_02203 A1O9_02203 A1O9_05093 A1O9_05093 A1O9_03012 A1O9_03012 A1O9_02928 A1O9_02928 A1O9_05442 A1O9_05442 A1O9_05761 A1O9_05761 A1O9_00457 A1O9_00457 A1O9_03343 A1O9_03343 A1O9_03490 A1O9_03490 A1O9_01565 A1O9_01565 A1O9_04813 A1O9_04813 A1O9_03077 A1O9_03077 A1O9_00613 A1O9_00613 A1O9_01247 A1O9_01247 A1O9_10265 A1O9_10265 A1O9_09524 A1O9_09524 A1O9_08669 A1O9_08669 A1O9_08192 A1O9_08192 A1O9_08776 A1O9_08776 A1O9_08417 A1O9_08417 A1O9_07536 A1O9_07536 FEN1 FEN1 A1O9_08053 A1O9_08053 A1O9_07001 A1O9_07001 A1O9_07076 A1O9_07076 A1O9_08024 A1O9_08024 A1O9_07133 A1O9_07133 A1O9_05354 A1O9_05354 A1O9_10535 A1O9_10535 A1O9_09895 A1O9_09895 A1O9_06318 A1O9_06318 A1O9_08668 A1O9_08668 A1O9_09520 A1O9_09520 A1O9_09495 A1O9_09495 A1O9_09884 A1O9_09884 A1O9_10052 A1O9_10052 A1O9_09789 A1O9_09789 A1O9_10071 A1O9_10071 A1O9_10770 A1O9_10770 A1O9_10449 A1O9_10449 A1O9_10379 A1O9_10379 A1O9_11365 A1O9_11365 A1O9_10777 A1O9_10777 A1O9_11825 A1O9_11825 A1O9_11181 A1O9_11181 A1O9_12186 A1O9_12186 A1O9_11758 A1O9_11758 A1O9_12214 A1O9_12214 MCM7 MCM7 A1O9_13085 A1O9_13085 A1O9_04555 A1O9_04555
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1O9_04827CMGC/CDK/CDK5 protein kinase; Belongs to the protein kinase superfamily. (413 aa)
A1O9_04582DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
A1O9_08185Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (673 aa)
A1O9_08215Uncharacterized protein. (364 aa)
A1O9_04924DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (503 aa)
A1O9_04147AAA domain-containing protein. (397 aa)
A1O9_04916AAA domain-containing protein. (558 aa)
A1O9_08531DNA polymerase. (1105 aa)
A1O9_04686DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (246 aa)
A1O9_02203RING-box protein 1. (123 aa)
A1O9_05093Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
A1O9_03012BTB domain-containing protein. (404 aa)
A1O9_02928Uncharacterized protein. (532 aa)
A1O9_05442DNA replication complex GINS protein psf3. (181 aa)
A1O9_05761DNA helicase; Belongs to the MCM family. (848 aa)
A1O9_00457DNA primase; Belongs to the eukaryotic-type primase small subunit family. (528 aa)
A1O9_03343Replication factor C subunit 4. (351 aa)
A1O9_03490Rad21_Rec8 domain-containing protein. (617 aa)
A1O9_01565DNA helicase; Belongs to the MCM family. (722 aa)
A1O9_04813CMGC/CDK/CDC2 protein kinase. (329 aa)
A1O9_03077DNA helicase; Belongs to the MCM family. (958 aa)
A1O9_00613Ubiquitin-40S ribosomal protein S27a. (154 aa)
A1O9_01247Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (403 aa)
A1O9_10265Cell division control protein; Belongs to the CDC6/cdc18 family. (628 aa)
A1O9_09524DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (255 aa)
A1O9_08669Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (221 aa)
A1O9_08192Uncharacterized protein. (132 aa)
A1O9_08776DNA helicase; Belongs to the MCM family. (904 aa)
A1O9_08417DNA polymerase delta subunit 4. (225 aa)
A1O9_07536Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (280 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (357 aa)
A1O9_08053BZIP domain-containing protein. (262 aa)
A1O9_07001CBFD_NFYB_HMF domain-containing protein. (333 aa)
A1O9_07076DNA ligase. (899 aa)
A1O9_08024GINS complex subunit 1. (229 aa)
A1O9_07133Uncharacterized protein. (469 aa)
A1O9_05354Replication factor C subunit 5. (354 aa)
A1O9_10535DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (652 aa)
A1O9_09895AAA domain-containing protein. (1070 aa)
A1O9_06318Replication factor C subunit 1. (1076 aa)
A1O9_08668Vezatin domain-containing protein. (589 aa)
A1O9_09520Uncharacterized protein. (347 aa)
A1O9_09495Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (104 aa)
A1O9_09884Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (752 aa)
A1O9_10052Uncharacterized protein. (513 aa)
A1O9_09789Uncharacterized protein. (406 aa)
A1O9_10071DNA polymerase delta subunit 2. (508 aa)
A1O9_10770DNA replication ATP-dependent helicase Dna2. (1701 aa)
A1O9_10449Uncharacterized protein. (508 aa)
A1O9_10379CBFD_NFYB_HMF domain-containing protein. (189 aa)
A1O9_11365DNA helicase; Belongs to the MCM family. (1005 aa)
A1O9_10777G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (472 aa)
A1O9_11825DNA ligase. (864 aa)
A1O9_11181Uncharacterized protein. (147 aa)
A1O9_12186Zds_C domain-containing protein. (820 aa)
A1O9_11758DNA_pol_E_B domain-containing protein. (852 aa)
A1O9_12214Replication factor C subunit 3/5. (408 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
A1O9_13085Uncharacterized protein; Belongs to the SKP1 family. (637 aa)
A1O9_04555DNA polymerase. (1449 aa)
Your Current Organism:
Exophiala aquamarina
NCBI taxonomy Id: 1182545
Other names: E. aquamarina CBS 119918, Exophiala aquamarina CBS 119918
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.