40 items (Exophiala aquamarina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A1O9_01047	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (421 aa)
	A1O9_00927	RING-type domain-containing protein. (270 aa)
	A1O9_01077	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1076 aa)
	A1O9_01261	RPOL9 domain-containing protein. (111 aa)
	A1O9_03858	CDC73_C domain-containing protein. (443 aa)
	A1O9_02096	Uncharacterized protein. (1240 aa)
	A1O9_01433	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (466 aa)
	A1O9_12264	DNA-directed RNA polymerase II subunit RPB3. (336 aa)
	A1O9_12113	DNA-directed RNA polymerase II subunit RPB7. (167 aa)
	A1O9_11760	Nuclear cap-binding protein subunit 2. (175 aa)
	A1O9_12114	Uncharacterized protein. (552 aa)
	A1O9_12195	DNA excision repair protein ERCC-3. (846 aa)
	A1O9_11685	DNA repair helicase rad15. (774 aa)
	A1O9_11469	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (853 aa)
	A1O9_09465	TFIIS N-terminal domain-containing protein. (396 aa)
	A1O9_08853	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (715 aa)
	A1O9_07640	Uncharacterized protein. (426 aa)
	A1O9_07627	Uncharacterized protein. (80 aa)
	A1O9_06798	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1763 aa)
	A1O9_06795	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1260 aa)
	A1O9_11575	DNA-directed RNA polymerase I, II, and III subunit RPABC1. (238 aa)
	A1O9_07156	DNA-directed RNA polymerase I, II, and III subunit RPABC5. (72 aa)
	A1O9_10841	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	A1O9_05517	Uncharacterized protein. (634 aa)
	A1O9_05960	Uncharacterized protein. (530 aa)
	A1O9_10247	RNA_pol_L_2 domain-containing protein. (412 aa)
	A1O9_04657	Uncharacterized protein. (553 aa)
	A1O9_04999	RPOL4c domain-containing protein. (152 aa)
	A1O9_08385	Uncharacterized protein. (436 aa)
	A1O9_05021	Uncharacterized protein. (119 aa)
	A1O9_07671	Uncharacterized protein. (382 aa)
	A1O9_02018	CYCLIN domain-containing protein; Belongs to the cyclin family. (388 aa)
	A1O9_02543	Uncharacterized protein. (609 aa)
	A1O9_02762	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (118 aa)
	A1O9_03172	Uncharacterized protein. (844 aa)
	A1O9_03342	CFEM domain-containing protein. (281 aa)
	A1O9_00331	Plus3 domain-containing protein. (610 aa)
	A1O9_05740	Uncharacterized protein. (669 aa)
	A1O9_00587	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1424 aa)
	A1O9_00520	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (499 aa)

Your Current Organism:

Exophiala aquamarina

NCBI taxonomy Id: 1182545
Other names: E. aquamarina CBS 119918, Exophiala aquamarina CBS 119918

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1O9_00331	A1O9_00587	A0A072PQJ4	A0A072PR73	Plus3 domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.941
A1O9_00331	A1O9_01077	A0A072PQJ4	A0A072PT93	Plus3 domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.971
A1O9_00331	A1O9_01261	A0A072PQJ4	A0A072PTA1	Plus3 domain-containing protein.	RPOL9 domain-containing protein.	0.904
A1O9_00331	A1O9_02096	A0A072PQJ4	A0A072PY42	Plus3 domain-containing protein.	Uncharacterized protein.	0.995
A1O9_00331	A1O9_02543	A0A072PQJ4	A0A072PLK6	Plus3 domain-containing protein.	Uncharacterized protein.	0.953
A1O9_00331	A1O9_02762	A0A072PQJ4	A0A072PN68	Plus3 domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.941
A1O9_00331	A1O9_03342	A0A072PQJ4	A0A072PQ08	Plus3 domain-containing protein.	CFEM domain-containing protein.	0.915
A1O9_00331	A1O9_03858	A0A072PQJ4	A0A072PTY7	Plus3 domain-containing protein.	CDC73_C domain-containing protein.	0.994
A1O9_00331	A1O9_04657	A0A072PQJ4	A0A072PIA0	Plus3 domain-containing protein.	Uncharacterized protein.	0.995
A1O9_00331	A1O9_04999	A0A072PQJ4	A0A072PJ47	Plus3 domain-containing protein.	RPOL4c domain-containing protein.	0.906
A1O9_00331	A1O9_05021	A0A072PQJ4	A0A072PJV8	Plus3 domain-containing protein.	Uncharacterized protein.	0.882
A1O9_00331	A1O9_05960	A0A072PQJ4	A0A072PE30	Plus3 domain-containing protein.	Uncharacterized protein.	0.999
A1O9_00331	A1O9_06795	A0A072PQJ4	A0A072P9Q1	Plus3 domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.929
A1O9_00331	A1O9_06798	A0A072PQJ4	A0A072P907	Plus3 domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.953
A1O9_00331	A1O9_07156	A0A072PQJ4	A0A072PAR2	Plus3 domain-containing protein.	DNA-directed RNA polymerase I, II, and III subunit RPABC5.	0.894
A1O9_00331	A1O9_07627	A0A072PQJ4	A0A072P849	Plus3 domain-containing protein.	Uncharacterized protein.	0.894
A1O9_00331	A1O9_09465	A0A072PQJ4	A0A072P2J3	Plus3 domain-containing protein.	TFIIS N-terminal domain-containing protein.	0.894
A1O9_00331	A1O9_10247	A0A072PQJ4	A0A072PE77	Plus3 domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.877
A1O9_00331	A1O9_10841	A0A072PQJ4	A0A072PBJ2	Plus3 domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.882
A1O9_00331	A1O9_11575	A0A072PQJ4	A0A072P9X3	Plus3 domain-containing protein.	DNA-directed RNA polymerase I, II, and III subunit RPABC1.	0.884