STRINGSTRING
AIZ46390.1 AIZ46390.1 AIZ44198.1 AIZ44198.1 AIZ44227.1 AIZ44227.1 AIZ44291.1 AIZ44291.1 pckA pckA sucD sucD sucC sucC gabD gabD ppc ppc AIZ45351.1 AIZ45351.1 AIZ45352.1 AIZ45352.1 AIZ45353.1 AIZ45353.1 AIZ45354.1 AIZ45354.1 AIZ45579.1 AIZ45579.1 AIZ45697.1 AIZ45697.1 AIZ45783.1 AIZ45783.1 AIZ45864.1 AIZ45864.1 pdhA pdhA AIZ45876.1 AIZ45876.1 AIZ45877.1 AIZ45877.1 AIZ46692.1 AIZ46692.1 AIZ45908.1 AIZ45908.1 AIZ46022.1 AIZ46022.1 AIZ46023.1 AIZ46023.1 sucA sucA AIZ46063.1 AIZ46063.1 mdh mdh AIZ46215.1 AIZ46215.1 gabD-2 gabD-2 AIZ46255.1 AIZ46255.1 AIZ46257.1 AIZ46257.1 AIZ46260.1 AIZ46260.1 fumC fumC AIZ46767.1 AIZ46767.1 AIZ46303.1 AIZ46303.1 AIZ46304.1 AIZ46304.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIZ46390.1Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
AIZ44198.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
AIZ44227.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (431 aa)
AIZ44291.1E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
sucDsuccinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
gabDSuccinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (824 aa)
AIZ45351.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
AIZ45352.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
AIZ45353.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
AIZ45354.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AIZ45579.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AIZ45697.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (907 aa)
AIZ45783.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AIZ45864.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (387 aa)
AIZ45876.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
AIZ45877.1Branched-chain amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (343 aa)
AIZ46692.1Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AIZ45908.1Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
AIZ46022.1Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AIZ46023.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (909 aa)
sucASucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (950 aa)
AIZ46063.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa)
AIZ46215.1malyl-CoA thiolesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (290 aa)
gabD-2Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AIZ46255.1Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (526 aa)
AIZ46257.1Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AIZ46260.1Malate dehydrogenase; Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
AIZ46767.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
AIZ46303.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AIZ46304.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
Your Current Organism:
Deinococcus swuensis
NCBI taxonomy Id: 1182571
Other names: D. swuensis, Deinococcus sp. DY59, Deinococcus swuensis Lee et al. 2015, JCM 18581, KCTC 33033, strain DY59
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