STRINGSTRING
Py04_0014 Py04_0014 secG secG secE secE Py04_0096 Py04_0096 Py04_0283 Py04_0283 secF secF secD secD Py04_0347 Py04_0347 Py04_0348 Py04_0348 Py04_0413 Py04_0413 cobD cobD cobQ cobQ Py04_0551 Py04_0551 Py04_0554 Py04_0554 Py04_0555 Py04_0555 Py04_0696 Py04_0696 Py04_0718 Py04_0718 Py04_0753 Py04_0753 Py04_0916 Py04_0916 Py04_0925 Py04_0925 Py04_0928 Py04_0928 Py04_0938 Py04_0938 Py04_0967 Py04_0967 Py04_0983 Py04_0983 Py04_1014 Py04_1014 Py04_1015 Py04_1015 Py04_1065 Py04_1065 Py04_1088 Py04_1088 Py04_1219 Py04_1219 Py04_1223 Py04_1223 Py04_1237 Py04_1237 Py04_1339 Py04_1339 Py04_1340 Py04_1340 nac nac Py04_1421 Py04_1421 Py04_1423 Py04_1423 ftsY ftsY srp54 srp54 Py04_1674 Py04_1674 secY secY Py04_1776 Py04_1776 srp19 srp19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Py04_0014Hypothetical protein; COG0457. (364 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. (56 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (61 aa)
Py04_0096Putative biotin biosynthesis protein; COG1268. (168 aa)
Py04_0283Putative Multiple antibiotic resistance (Mar)-related protein; COG2095. (202 aa)
secFPutative preprotein translocase subunit SecF; Involved in protein export. (282 aa)
secDPutative preprotein translocase subunit SecD; Involved in protein export. (505 aa)
Py04_0347ABC transport ATP binding protein; COG0444. (282 aa)
Py04_0348Dipeptide ABC transporter ATP-binding protein; COG4608. (335 aa)
Py04_0413putativeMembrane transport protein, MMPL type; COG1033. (745 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (291 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (463 aa)
Py04_0551Putative dipeptide transport protein precursor; COG0747. (634 aa)
Py04_0554Putative peptide ABC uptake protein; COG0444. (321 aa)
Py04_0555Dipeptide ABC transporter ATP-binding protein; COG4608. (246 aa)
Py04_0696Hypothetical protein containing Sodium:alanine symporter domain; COG1115. (517 aa)
Py04_0718Multiple antibiotic resistance protein related protein; COG2095. (200 aa)
Py04_0753Putative multidrug ABC transporter ATPase; COG1131. (233 aa)
Py04_0916Multidrug ABC transporter ATPase; COG1131. (283 aa)
Py04_0925ABC transporter ATP-binding protein; COG1131. (228 aa)
Py04_0928Putative nonsense-mediated mRNA decay protein; COG1499. (387 aa)
Py04_0938Hydroxymethylpyrimidine transporter CytX; COG1457. (416 aa)
Py04_0967ABC transporter ATP-binding protein; COG1131. (255 aa)
Py04_0983Proline permease; COG0591; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (492 aa)
Py04_1014Dipeptide ABC transporter ATPase; COG4608. (329 aa)
Py04_1015Dipeptide ABC transporter ATPase; COG0444. (303 aa)
Py04_1065Xanthine/uracilpermease; COG2252. (443 aa)
Py04_1088Hypothetical protein; COG2431. (197 aa)
Py04_1219Multidrug ABC transporter ATPase; COG1131. (307 aa)
Py04_1223Proline permease (putP-2); COG0591; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (480 aa)
Py04_1237Putative thiamin-binding periplasmic protein; COG4143. (351 aa)
Py04_1339Dipeptide ABC transporter ATP-binding protein; COG4608. (326 aa)
Py04_1340Peptide ABC transporter atp-binding protein; COG0444. (326 aa)
nacPutative nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (109 aa)
Py04_1421Hypothetical protein; COG0622. (170 aa)
Py04_1423Putative ABC transporter ATP-binding protein; COG1131. (242 aa)
ftsYSignal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (322 aa)
srp54Signal recognition particle protein Srp54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (443 aa)
Py04_1674Hypothetical protein; COG0622. (164 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (468 aa)
Py04_1776Putative multidrug ABC transporter ATPase; COG1131. (318 aa)
srp19Signal recognition particle protein Srp19; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (100 aa)
Your Current Organism:
Pyrococcus sp. ST04
NCBI taxonomy Id: 1183377
Other names: P. sp. ST04
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